The impact of medication shortages on paediatric care: A retrospective impact analysis
Aims Medication shortages are a growing global concern, with potentially greater consequences in paediatric patients because of the limited availability of safe, evidence‐based and appropriately formulated medication. This study aimed to evaluate the impact of medication shortages on paediatric patients by assessing the suitability and safety of ...
Maaike Johanna Rutten ‐ van Kranenburg +6 more
wiley +1 more source
Inflammation contributes to axon reflex vasodilatation evoked by iontophoresis of an alpha-1 adrenoceptor agonist [PDF]
Iontophoresis of aradrenoceptor agonists in the human forearm evoke axon reflex vasodilatation, possibly due to an accumulation of inflammatory agents at the site of iontophoresis.
Drummond, P.D.
core
Dexamethasone Reduced Clonidine-induced Hypoactivity in Mice
Reduced clonidine anti-nociception in mice given low doses of dexamethasone has encouraged us to investigate the effects of dexamethasone pretreatment on locomotor hypoactivity, another example of clonidine-induced behaviour in mice ...
A Capasso +4 more
core +1 more source
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed +7 more
wiley +1 more source
Gabapentin versus Clonidine Premedication for Haemodynamic Stability and Postoperative Analgesia in Laparoscopic Cholecystectomy: A Randomised Double-blind Control Study [PDF]
Introduction: Laparoscopic cholecystectomy is associated with haemodynamic stress responses and significant postoperative pain due to CO2 insufflation and peritoneal irritation.
Mahima Manchanda +4 more
doaj +1 more source
Paediatric clonidine medication errors: Findings from a multicentre French study
Aims This study aimed to describe the characteristics of medication errors involving clonidine in paediatric patients and reported to French Network of Pharmacovigilance and Poison Control Centres. Methods This retrospective observational study analysed clonidine‐related medication errors reported between 1985 and June 2024 in patients under 12 years ...
Eve‐Marie Thillard +8 more
wiley +1 more source
KBG syndrome: A scoping review of electroclinical features of patients with epilepsy
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini +6 more
wiley +1 more source
Background The effect of adding clonidine to local anesthetics for nerve or plexus blocks remains unclear. Most of the studies in adults have demonstrated the positive effects of clonidine on intra- and postoperative analgesia when used as an adjunctive ...
Petroheilou Kalliopi +4 more
doaj +1 more source
Baroreflex Failure After Surgical Resection of Bilateral Carotid Body Tumors: A Systematic Review
ABSTRACT Objective Surgery remains the definitive treatment for carotid body tumors (CBTs); however, concern persists regarding the risk of baroreflex failure (BRF) following bilateral CBT resection. The true incidence and long‐term clinical course of BRF remain poorly defined. We performed a systematic review to examine the risk and clinical course of
Alex Z. Graboyes +8 more
wiley +1 more source
The effect of oral clonidine premedication on blood loss in primary total hip arthroplasty: A randomized placebo-controlled trial [PDF]
Background: Substantial blood loss is a major concern in primary total hip arthroplasty and thus various blood conservation techniques are used to reduce blood loss in this surgery.
Shideh Dabir +6 more
doaj +1 more source

