Results 21 to 30 of about 31,656 (234)
Clonidine Use for the Treatment of Nightmares in Posttraumatic Stress Disorder
Introduction. While clonidine is used clinically for the treatment of nightmares in posttraumatic stress disorder (PTSD), few case reports demonstrating this indication exist, and there have been few studies investigating clonidine’s mechanism of action ...
Jill S. Bange, Kelly E. Melvin
doaj +1 more source
The effect of ritonavir on the pharmacokinetics of clonidine
This project aims to explore the repercussions of ritonavir on both the drug kinetics of clonidine in rats and clonidine metabolism in liver microsomes.
in vivo +4 more
doaj +1 more source
Background Clonidine hydrochloride is used to treat sedative agent withdrawals, malignant hypertension, and anesthesia complications. Clonidine is also prescribed off-label to pediatric patients at a dose of 1 μg/kg.
Jumpei Saito +7 more
doaj +1 more source
Background: The laparoscopic surgical procedure has made remarkable changes in the surgical field. Conditions, such as pneumoperitoneum, has an impact on several homeostatic systems.
Sindhuja Somasundaram +1 more
doaj +1 more source
The intravenous pharmacotherapy of critically ill patients is extremely challenging due to the high number of drugs administered. We therefore evaluated the physicochemical compatibility of combinations of clonidine with drugs frequently used in an ...
Anna Katharina Koller +2 more
doaj +1 more source
Clonidine, an alpha-2 adrenergic agonist, has been proposed as an antimanic agent that acts by reducing noradrenergic transmission. We conducted a systematic review to examine the efficacy and safety of clonidine for acute mania/hypomania.
Prakamya Singal +5 more
doaj +1 more source
Efficacy of low dose intravenous dexmedetomidine versus clonidine in treatment of shivering during caesarean section under spinal anaesthesia: a double blind randomized controlled trial [PDF]
Objectives: Dexmedetomidine and clonidine have been used to prevent and treat shivering after spinal anaesthesia. A double blind randomized controlled trial was conducted to compare the efficacy and safety of low dose intravenous dexmedetomidine and ...
Karamchand Basumatary +5 more
doaj +1 more source
Effects of clonidine on the activity of the rat glutamate transporter EAAT3 expressed in oocytes [PDF]
BackgroundClonidine has been shown to be a potent neuroprotectant by acting at α2 receptors on glutamatergic neurons to inhibit the release of glutamate.
Jae Hee Woo +3 more
doaj +1 more source
Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano +10 more
wiley +1 more source
Pharmacokinetics of Orally Administered Clonidine in Dogs. [PDF]
ABSTRACT Clonidine is an α‐2 agonist shown to be both well tolerated and useful in the treatment of canine fear‐based disorders, although it is perceived to have a short duration of action. Clonidine is available in regular release and extended‐release formulations, but canine pharmacokinetic (PK) and pharmacodynamic (PD) data on any clonidine ...
Pflaum K, Albright J, Cox S, Smith J.
europepmc +2 more sources

