Results 111 to 120 of about 805,120 (315)

Cloning characterisation and expression of a G-protein-couple receptor from Lymnaea stagnalis and identification of a leucokinin-like peptide PSFHSWSamide as its endogenous ligand [PDF]

, 1997
No description ...
Burke, Julian F, Cox, Kingsley J A, Geraerts, Wijnand P M, Li, Ka Wan, Tensen, Cornelis P, Van der Schors, Roel C, van Heerikhuizen, Harm, Vreugdenhil, Erno   +7 more
core   +1 more source

Molecular, Enzymatic, and Cellular Characterization of Soluble Adenylyl Cyclase From Aquatic Animals. [PDF]

, 2018
The enzyme soluble adenylyl cyclase (sAC) is the most recently identified source of the messenger molecule cyclic adenosine monophosphate. sAC is evolutionarily conserved from cyanobacteria to human, is directly stimulated by [Formula: see text] ions ...
Acin-Perez, Barott, Barott, Barott, Beltrán, Berthelot, Bitterman, Bordeaux, Braun, Braun, Braun, Buck, Camacho Londoño, Chaloupka, Chen, Chen, Cooper, De Rasmo, Di Benedetto, Elliott, Farrell, Geng, Goldberg, Gordeladze, Hess, Hrdlickova, Jaiswal, Kobayashi, Leparc, Levin, Litvin, Magro, Neer, Neer, Nomura, Nomura, Ramos-Espiritu, Roa, Roa, Roa, Salem, Salomon, Schwencke, Steegborn, Steegborn, Stessin, Structural Genomics Consortium, Tresguerres, Tresguerres, Tresguerres, Tresguerres, Tresguerres, Wilson, Yeo, Zaccolo, Zippin, Zippin, Zippin, Zippin   +58 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Molecular Cloning of Monkey Histamine H4 Receptor

Journal of Pharmacological Sciences, 2005
Histamine H4 receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H4 receptor was identified.
Tamaki Oda, Shun-ichiro Matsumoto, Mitsuyuki Matsumoto, Jun Takasaki, Masazumi Kamohara, Takatoshi Soga, Hideki Hiyama, Masato Kobori, Masao Katoh   +8 more
doaj   +1 more source

Characterization of Arabidopsis thaliana CPR5 via the elucidation of interacting protein partners : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]

, 2015
he Arabidopsis thaliana Constitutive expresser of pathogenesis related genes5 (CPR5) has previously been suggested to play a role in the regulation of disease resistance, plant and cell proliferation, development and death.
Chiem, Fiona (Shane)
core  

Spicy science: David Julius and the discovery of temperature-sensitive TRP channels. [PDF]

, 2015
This invited biographical review covers the career of Dr. David Julius and his discovery of thermosensitive TRP channels. Dr. Julius is currently the Morris Herzstein Chair in Molecular Biology and Medicine and Professor and Chair of Physiology at the ...
Bautista, Diana
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Cloning, Molecular Characterization and Expression Patterns of DMRTC2 Implicated in Germ Cell Development of Male Tibetan Sheep. [PDF]

Int J Mol Sci, 2020
Li T, Zhang H, Wang X, Yin E, Chen N, Kang L, Zhao X, Ma Y.   +7 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source