Results 211 to 220 of about 814,547 (292)

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak, Marcell Papp, Carolina Paganini, Andrea Zendrini, Paolo Bergese, Dorothea Pinotsi, Paolo Arosio   +6 more
wiley   +1 more source

Cloning and Functional Analysis of the Aldehyde Dehydrogenase Gene <i>VvALDH</i> in the IAA Synthesis Pathway of <i>Volvariella volvacea</i>. [PDF]

J Fungi (Basel)
Mao M, Hou L, Ma L, Jiang N, Lin J, Qu S, Li H, Xu P, Liu D, Ji W.   +9 more
europepmc   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Cytosolic TOP3α facilitates mitochondrial DNA sensing by cGAS. [PDF]

EMBO Rep
Cai D, Chen C, Meekrathok P, Zeng W, Wang Z, Peng Z, Mo Y, Xu X, Wang J, Qiu J.   +9 more
europepmc   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

Construction and Diversification of Natural Product Biosynthetic Gene Clusters at High Efficiency and Accuracy. [PDF]

ACS Synth Biol
Bai C, Bayona LM, van Wezel GP.
europepmc   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

Cloning and functional analysis of the TERE1 gene using the Gal4-UaS system in S2 cells: A streamlined approach for human gene functional genomics. [PDF]

J Genet Eng Biotechnol
Dragh MA, Al-Allak ZS, Allami ZZ.
europepmc   +1 more source

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, EarlyView.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source