Advanced Materials, EarlyView.Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu +10 more
wiley +1 more source
Asilomar, Gene Cloning's Origins, and Its Commercial Fate. [PDF]
J Hist BiolYi D.
europepmc +1 more source
Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance
Advanced Materials, EarlyView.This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee +14 more
wiley +1 more source
An improved toolkit of gateway- and gibson assembly-compatible vectors for protoplast transfection and agrobacterium-mediated plant transformation. [PDF]
BMC Res NotesAllen JR +5 more
europepmc +1 more source
Advanced Materials, EarlyView.We report a 3.2 Å cryoEM structure of functional amyloid protein FapC from Pseudomonas sp. UK4, an essential component of bacterial biofilm, which reveals a Greek key‐shaped protofilament, supports bioinformatically determined motifs, nuances AlphaFold predictions, emphasizes heterogeneous cross‐β stacking in amyloid cross‐seeding and shows strain ...
Yanting Jiang +13 more
wiley +1 more source
I-PREFR: Inverse PCR-Based Restriction Enzyme FRee Unidirectional Strategy for Rapid Markerless Chromosomal Gene Deletion and Reconstitution in Bacteria Using Suicide Vectors. [PDF]
Bio ProtocRana R, Sharma A, Dutta A, Patil PB.
europepmc +1 more source
Cloning an industry: Strategy typologies of Shanghai biotechnology companies
, 1969 Ken Malone +4 more
openalex +2 more sources
<i>PIK3R1</i> and <i>G0S2</i> are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation. [PDF]
EpigeneticsDaskeviciute D +13 more
europepmc +1 more source
An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels +7 more
wiley +1 more source