Results 111 to 120 of about 16,276 (198)

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 241-254, January 2026.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Clopidogrel Bisulfate [PDF]

, 2010
Maria L A D, Lestari, , Suciati, Gunawan, Indrayanto, Harry G, Brittain   +3 more
openaire   +2 more sources

Toward a More accurate, Evidence‐Based Classification of CYP Inhibitors: A Critical Appraisal of Current Systems

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 30-32, January 2026.
In this issue of CPT, Malavé et al. deliver a comprehensive reassessment of CYP2C19 inhibitor classifications through a systematic review of clinical drug–drug interaction (DDI) studies. While their findings bring clarity to specific discrepancies, this commentary explores the origins of such inconsistencies, particularly focusing on methodological ...
Janne T. Backman
wiley   +1 more source

Clopidogrel Management in Abdominal Surgery: A Comparison of Perioperative Bleeding Risks with Low-Molecular-Weight Heparin Bridging, No-Bridging and Clopidogrel Continuation Strategies

Clinical and Applied Thrombosis/Hemostasis
Clopidogrel is usually discontinued 5–7 days before elective surgery to reduce the risk of bleeding. However, the perioperative safety of patients receiving low-molecular-weight heparin (LMWH) bridging therapy or continuing clopidogrel therapy remains ...
Bangsheng Hu MD, Junsheng Chen MD, Shuai Han MD, Zeping Dai MD, PhD, Ju Gao MD, PhD   +4 more
doaj   +1 more source

Decreased platelet responsiveness to clopidogrel correlates with CYP2C19 and PON1 polymorphisms in atherosclerotic patients

, 2019
Júlio Flávio Meirelles Marchini, Marcelo R. Pinto, Gustavo Caires Novaes, André Badran, Rafael Brolio Pavão, Geraldo Luiz de Figueiredo, Igor Matos Lago, M.O. Lima-Filho, D.C. Lemos, Monique Tonani, Cleide Marques Antloga, Lucas Ferrari de Oliveira, Julio C. C. Lorenzi, José Antônio Marin‐Neto   +13 more
openalex   +1 more source

Predictors of 12‐Month MACE Among Diabetic, Prediabetic, and Normoglycemic Patients Undergoing Elective Percutaneous Coronary Intervention: 10 Years' Experience From Tehran Heart Center

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Elevated blood glucose levels in diabetes and prediabetes contribute to vascular inflammation and may increase the risk of major adverse cardiac events (MACE). We sought to evaluate the association between different glycemic statuses and 12‐month MACE in patients undergoing elective percutaneous coronary intervention (PCI ...
Ali Hosseinsabet, Nasrin Etesamifard, Akbar Shafiee, Arash Jalali, Amirhossein Heidari, Nazila Heidari, Hamid Ariannejad, Hassan Aghajani   +7 more
wiley   +1 more source

The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

Journal of Veterinary Internal Medicine
Background Some studies in humans show that the concurrent use of clopidogrel and omeprazole decreases plasma clopidogrel active metabolite (CAM) concentrations and clopidogrel antiplatelet effects. Whether this drug interaction occurs in cats is unknown.
Christina Plante, Pamela M. Lee, Jillian M. Haines, O. Lynne Nelson, Stephanie E. Martinez, Michael H. Court   +5 more
doaj   +1 more source

Stability of Medications Administered via Enteral Feeding Tubes: A Systematic Review

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
The graphical abstract for the stability of medicatioins administred via enteral feeding tube: A systematic review ((PROSPERO, registration number: CRD42024580820)). ABSTRACT Feeding tubes are essential for patients unable to maintain adequate oral intake, serving multiple purposes including nutrition delivery and medication administration.
Lena Alodat, Wejdan Shahin, Lina Breik, Ayman Allahham   +3 more
wiley   +1 more source

Development and Validation of a Multigene Panel for Pharmacogenomics Testing Using Next‐Generation Sequencing for Routine Clinical Practice

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Pharmacogenomics (PGx) is a rapidly evolving field that aims to personalize medicine by identifying genetic variations that influence drug response. While next‐generation sequencing (NGS)–based applications are not yet widely adopted in clinical routine, this study aimed to validate 9 genes of the NGS‐based Ion AmpliSeq Pharmacogenomics Panel ...
Yaowaluck Hongkaew, Pattapon Kunadirek, Montinee Sangtian, Prangwan Pateetin, Srichan Bunlungsup, Wipa Panmontha, Sornsawan Kawprasertsri, Tanawat Khunlertkit   +7 more
wiley   +1 more source

Atividade plaquetar residual em doentes tratados com clopidogrel. Implicações para a orientação de doentes após síndroma coronária aguda

, 2012
João Morais
openalex   +1 more source