Results 201 to 210 of about 141,477 (341)

Cellular and molecular cross‐talk in atrial fibrillation: The role of non‐cardiomyocytes in creating an arrhythmogenic substrate

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of cellular and molecular cross‐talk in atrial fibrillation. Left: a schematic of cardiac tissue showing cardiomyocytes, fibroblasts, adipocytes, inflammatory cells and the coagulation system. Right: direct and indirect cross‐talk between different cell types, with the impact of direct cross‐talk on action potential (
Zhenyu Dong, Ruben Coronel, Joris R. de Groot   +2 more
wiley   +1 more source

Post-acute care and secondary prevention after ischaemic stroke [PDF]

, 2011
Higgins, P., Langhorne, P., McArthur, K.S., Quinn, T.J.   +3 more
core   +1 more source

A case of hemobilia caused by a pseudoaneurysm resulting in obstructive cholangitis in a patient who underwent plastic stent placement for pancreatic cancer (with video)

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Hemobilia, or hemorrhage within the biliary system, is an uncommon cause of stent obstruction associated with bile duct strictures that are rarely observed with plastic stents. Reports of a pseudoaneurysm as a cause of hemobilia after plastic stent placement are also rare.
Yusuke Seyama, Akinori Sugaya, Ken Koyama, Hiroyuki Honda, Hajime Ishibashi, Masaharu Yamaoka, Mitsuharu Ozeki, Mitsuhide Goto, Masahiro Araki, Kenji Amagai   +9 more
wiley   +1 more source

Clopidogrel Management in Abdominal Surgery: A Comparison of Perioperative Bleeding Risks with Low-Molecular-Weight Heparin Bridging, No-Bridging and Clopidogrel Continuation Strategies

Clinical and Applied Thrombosis/Hemostasis
Clopidogrel is usually discontinued 5–7 days before elective surgery to reduce the risk of bleeding. However, the perioperative safety of patients receiving low-molecular-weight heparin (LMWH) bridging therapy or continuing clopidogrel therapy remains ...
Bangsheng Hu MD, Junsheng Chen MD, Shuai Han MD, Zeping Dai MD, PhD, Ju Gao MD, PhD   +4 more
doaj   +1 more source

The Risk of Colonoscopy‐related Bleeding in Patients With or Without Continued Treatment With an Antithrombotic Agent

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives We prospectively investigated the risk of colonoscopy‐related bleeding in relation to antithrombotic treatment. Methods This prospective, observational, single‐center cohort study (NCT02594813) enrolled consecutive patients who underwent colonoscopy, including the removal of colorectal polyps, regardless of the continuation of ...
Emi Nonaka, Ichitaro Horiuchi, Akira Horiuchi, Satoshi Ukai, Noriko Takahata, Kimihiko Oishi   +5 more
wiley   +1 more source

The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

Journal of Veterinary Internal Medicine
Background Some studies in humans show that the concurrent use of clopidogrel and omeprazole decreases plasma clopidogrel active metabolite (CAM) concentrations and clopidogrel antiplatelet effects. Whether this drug interaction occurs in cats is unknown.
Christina Plante, Pamela M. Lee, Jillian M. Haines, O. Lynne Nelson, Stephanie E. Martinez, Michael H. Court   +5 more
doaj   +1 more source

Consideration of ethnic differences in approvals for anti‐HIV medicines in Japan: Evaluation based on pharmacokinetic studies and post‐marketing data

British Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2474-2479, August 2025.
More than 30 anti‐HIV drugs have been approved in Japan using data from dossiers submitted to the United States or European regulatory authorities since 1998. These drugs were approved with the same dosage and administration regimes as in the United States and Europe, using data from pivotal studies that rarely included any Japanese patients, whereas ...
Rumiko Shimazawa, Masayuki Ikeda
wiley   +1 more source

PCV18: COST-EFFECTIVENESS OF PREVENTION OF ATHEROTHROMBOTIC DISEASE WITH ASPIRIN VERSUS CLOPIDOGREL IN GREECE

, 2000
Mary Geitona, John Kyriopoulos, C Geitonas, A. Papademetriou, Vassilios S. Nikolaou   +4 more
openalex   +1 more source

Pharmacogenomics in the UK National Health Service: Progress towards implementation

British Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2241-2250, August 2025.
Over the past decade there has been considerable and growing enthusiasm about the promise of using genomics to inform healthcare. In particular, using genetic data to inform prescribing practice has emerged as a compelling policy priority for health systems around the world, not least in the NHS.
John H. McDermott, Maria Tsakiroglou, William G. Newman, Munir Pirmohamed   +3 more
wiley   +1 more source

Suspected clopidogrel-associated hepatitis in a cat

Journal of Feline Medicine and Surgery Open Reports
Case summary Acute hepatitis and liver damage are rare adverse effects of clopidogrel in humans. In veterinary medicine, clopidogrel is mainly prescribed in the treatment of feline patients with cardiomyopathies.
Astrid L Kamp, Washma Yousofzai, Hans S Kooistra, Giorgia Santarelli, Ingeborg M van Geijlswijk   +4 more
doaj   +1 more source