Results 31 to 40 of about 125,001 (364)

Decreased platelet miR-199a-5p level might lead to high on-clopidogrel platelet reactivity in patients with coronary artery disease

Platelets, 2023
Clopidogrel combined with aspirin is widely used in coronary artery disease (CAD) patients, while some patients exhibit high platelet activity when receiving the combined treatment. Current environmental and genetic factors could only explain part of the
Xiaolei Hu, Mupeng Li, He Li, Peiyuan Song, Yanjiao Zhang, Gan Zhou, Jie Tang, Liming Peng, Qilin Ma, Xiaoping Chen   +9 more
doaj   +1 more source

Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke [PDF]

, 2008
Background Recurrent stroke is a frequent, disabling event after ischemic stroke. This study compared the efficacy and safety of two antiplatelet regimens — aspirin plus extendedrelease dipyridamole (ASA–ERDP) versus clopidogrel.
SACCO RL, DIENER HC, YUSUF S, COTTON D, OUNPUU S, LAWTON WA, PALESCH Y, MARTIN RH, ALBERS GW, BATH P, BORNSTEIN N, CHAN BP, CHEN ST, CUNHA L, DAHLÖF B, DE KEYSER J, DONNAN GA, ESTOL C, GORELICK P, GU V, HERMANSSON K, HILBRICH L, KASTE M, LU C, MACHNIG T, PAIS P, ROBERTS R, SKVORTSOVA V, TEAL P, TONI D, VANDERMAELEN C, VOIGT T, WEBER M, YOON BW, G.LEMBO, M.RASURA, M. SACCHETTI   +36 more
core   +4 more sources

Clopidogrel-induced pneumonia [PDF]

BMJ Case Reports, 2021
A 75-year-old man was admitted to our hospital with progressive dyspnoea on effort and cough. Three months before presentation, he had undergone percutaneous coronary intervention for unstable angina. At that time, he began taking aspirin (100 mg daily) and clopidogrel (75 mg daily).
Yoshitaka Tomoda, Chinami Nagasawa, Yukikazu Awaya, Takashi Miyajima   +3 more
openaire   +3 more sources

Thromboembolic and bleeding events in ICU patients with COVID‐19: A nationwide, observational study

Acta Anaesthesiologica Scandinavica, Volume 67, Issue 1, Page 76-85, January 2023., 2023
Abstract Background Intensive care unit (ICU) patients with Coronavirus disease 2019 (COVID‐19) have an increased risk of thromboembolic complications. We describe the occurrence of thromboembolic and bleeding events in all ICU patients with COVID‐19 in Denmark during the first and second waves of the pandemic.
Lene Russell, Sarah Weihe, Emilie Kabel Madsen, Christine Lodberg Hvas, Jens Wolfgang Leistner, Jens Michelsen, Anne Craveiro Brøchner, Anders Bastiansen, Frederik Mølgaard Nielsen, Nick Meier, Anne Sofie Andreasen, Niels‐Erik Ribergaard, Bodil Steen Rasmussen, Christoffer Grant Sølling, David Levarett Buck, Helle Bundgaard, Helle Scharling Pedersen, Iben Strøm Darfelt, Lone Musaeus Poulsen, Michael Ibsen, Ronni R. Plovsing, Sigurdur T. Sigurdsson, Susanne Iversen, Thomas Hildebrandt, Thomas Mohr, Ulrick Skipper Espelund, Vibeke Jørgensen, Nicolai Haase, Anders Perner   +28 more
wiley   +1 more source

Is clopidogrel better than aspirin following breakthrough strokes while on aspirin? A retrospective cohort study. [PDF]

, 2014
ObjectiveThere is insufficient evidence on which to base a recommendation for optimal antiplatelet therapy following a stroke while on aspirin. The objective was to compare clopidogrel initiation vs aspirin reinitiation for vascular risk reduction among ...
Chang, Ku-Chou, Lee, Hsuei-Chen, Lee, Jiann-Der, Lee, Meng, Lee, Tsong-Hai, Ovbiagele, Bruce, Rao, Neal M, Saver, Jeffrey L, Wang, Hui-Hsuan, Wu, Chih-Ying, Wu, Yi-Ling   +10 more
core   +1 more source

Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.

New England Journal of Medicine, 2020
BACKGROUND The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been ...
J. Brouwer, V. Nijenhuis, R. Delewi, R. Hermanides, W. Holvoet, C. Dubois, P. Frambach, B. de Bruyne, G. V. van Houwelingen, J. van der Heyden, P. Toušek, F. van der Kley, I. Buysschaert, C. Schotborgh, B. Ferdinande, P. van der Harst, J. Roosen, J. Peper, Frederick W F Thielen, L. Veenstra, D. R. Chan Pin Yin, M. Swaans, B. Rensing, A. W. van ’t Hof, L. Timmers, J. Kelder, P. Stella, J. Baan, J. T. ten Berg   +28 more
semanticscholar   +1 more source

The Role of Genetic Polymorphism and Other Factors on Clopidogrel Resistance (CR) in an Asian Population with Coronary Heart Disease (CHD)

Molecules, 2021
Clopidogrel is a widely-used antiplatelet drug. It is important for the treatment and prevention of coronary heart disease. Clopidogrel can effectively reduce platelet activity and therefore reduce stent thrombosis.
Mohammed Ahmed Akkaif, N. Daud, A. Sha’aban, M. L. Ng, M. A. S. Abdul Kader, D. Noor, B. Ibrahim   +6 more
semanticscholar   +1 more source

Systematic review and meta-analysis of optimal P2Y₁₂ blockade in dual antiplatelet therapy for patients with diabetes with acute coronary syndrome [PDF]

, 2016
Background: Patients with diabetes are at increased risk of acute coronary syndromes (ACS) and their mortality and morbidity outcomes are significantly worse following ACS events, independent of other comorbidities.
Brown, Oliver I, Hoye, Angela, Rossington, Jennifer A   +2 more
core   +1 more source

Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.

New England Journal of Medicine, 2020
BACKGROUND The roles of anticoagulation alone or with an antiplatelet agent after transcatheter aortic-valve implantation (TAVI) have not been well studied.
V. Nijenhuis, J. Brouwer, R. Delewi, R. Hermanides, W. Holvoet, C. Dubois, P. Frambach, B. de Bruyne, G. V. van Houwelingen, J. van der Heyden, P. Toušek, F. van der Kley, I. Buysschaert, C. Schotborgh, B. Ferdinande, P. van der Harst, J. Roosen, J. Peper, Frederick W F Thielen, L. Veenstra, D. R. Chan Pin Yin, M. Swaans, B. Rensing, A. W. van ’t Hof, L. Timmers, J. Kelder, P. Stella, J. Baan, J. T. ten Berg   +28 more
semanticscholar   +1 more source

Validation of a method for quantitation of the clopidogrel active metabolite, clopidogrel, clopidogrel carboxylic acid, and 2-oxo-clopidogrel in feline plasma [PDF]

Journal of Veterinary Cardiology, 2017
The clopidogrel active metabolite (CAM) is unstable and challenging to quantitate. The objective was to validate a new method for stabilization and quantitation of CAM, clopidogrel, and the inactive metabolites clopidogrel carboxylic acid and 2-oxo-clopiodgrel in feline plasma.Two healthy cats administered clopidogrel to demonstrate assay in vivo ...
Janne G. Lyngby, Michael H. Court, Pamela M. Lee   +2 more
openaire   +3 more sources