Results 61 to 70 of about 125,001 (364)

Outcome of stroke patients on clopidogrel plus proton-pump inhibitors: a single-center cohort study

open access: yesAnnals of Saudi Medicine, 2019
BACKGROUND: Recent studies suggest a higher risk of adverse cardiovascular outcome and mortality in patients co-prescribed clopidogrel with proton pump inhibitors (PPI). OBJECTIVE: Investigate the impact of concomitant prescription of clopidogrel and PPI
Rahaf A. Alghamdi   +4 more
doaj   +1 more source

Aspirin and Clopidogrel Resistance [PDF]

open access: yesMayo Clinic Proceedings, 2006
Despite aspirin's and clopidogrel's proven benefit in reducing cardiovascular (CV) events, recurrent CV events still occur in patients receiving antiplatelet therapy. Many of these patients are resistant or only partially responsive to the antiplatelet effects of aspirin and clopidogrel, as determined by standard platelet assays.
Richard A. Lange   +4 more
openaire   +3 more sources

Anti-platelet therapy: ADP receptor antagonists. [PDF]

open access: yes, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD
core   +2 more sources

Changes in Practice Patterns of Clopidogrel in Combination with Proton Pump Inhibitors after an FDA Safety Communication. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVES:In 2009, the FDA issued a warning that omeprazole--a proton pump inhibitor (PPI)--reduces the antithrombotic effect of clopidogrel by almost half when taken concomitantly.
Annie Guérin   +6 more
doaj   +1 more source

Bioactive food components and their inhibitory actions in multiple platelet pathways

open access: yesJournal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das   +7 more
wiley   +1 more source

Coming safely to a stop : a review of platelet activity after cessation of antiplatelet drugs [PDF]

open access: yes, 2015
Funding Isobel Ford is an employee of the University of Aberdeen. The research for the writing of this review received no specific grant from any funding agency in the public, commercial, or not-forprofit sectorsPeer ...
Ford, Isobel
core   +1 more source

The synthesis of clopidogrel [PDF]

open access: yesIOP Conference Series: Materials Science and Engineering, 2017
Cardiac and cerebrovascular disease is a common disease. It is well recognized that antiplatelet agent is effective in the prevention and treatment of thrombosis. Clopidogrel is one of thieno pyridine derivatives, which can inhibit ADP-induced platelet aggregation.
Yuanjun Huang, Qingxin Zhu
openaire   +1 more source

Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy

open access: yesJournal of Anatomy, Volume 242, Issue 1, Page 29-49, January 2023., 2023
Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone   +12 more
wiley   +1 more source

Dramatic effect of early clopidogrel administration in reducing mortality and MACE rates in ACS patients

open access: yesSwiss Medical Weekly, 2012
BACKGROUND: Patients who have acute coronary syndromes with or without ST-segment elevation have high rates of major vascular events. We evaluated the efficacy of early clopidogrel administration (300 mg) (
Jean Christophe Stauffer   +5 more
doaj   +1 more source

Adherence to secondary stroke prevention strategies - Results from the German stroke data bank [PDF]

open access: yes, 2003
Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies.
Busse, O.   +4 more
core   +1 more source

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