Results 21 to 30 of about 971 (151)
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023 Introduction Clopidogrel is recommended as an alternative to Acetyl Salicylic Acid (ASA), the first-line drug for secondary stroke prevention. Clopidogrel resistance in Indonesia is reportedly 15.8%.
Rakhmad Hidayat +8 more
doaj +1 more source
Thrombosis Journal, 2023 Objective Antiplatelet drugs, such as Aspirin and Clopidogrel (Plavix) are effective in the primary prevention of thromboembolic events. They are commonly used to reduce the risk of recurrence of thromboembolism.
Mohammad Parsa-kondelaji +1 more
doaj +1 more source
Ticagrelor Use in Indian Patients Undergoing Neuroendovascular Procedures: A Single Center Experience [PDF]
Neurointervention, 2019 Purpose A safe and efficacious antiplatelet drug is needed for patients with clopidogrel resistance who undergo neuroendovascular procedures. Ticagrelor is a new reversibly binding, oral, direct-acting P2Y receptor antagonist with no known resistance. We
Vivek Karan +3 more
doaj +1 more source
Effect of obesity and serum leptin level on clopidogrel resistance
Türk Kardiyoloji Derneği Arşivi, 2016 Objective: Clopidogrel inhibits platelet aggregation by blockade of platelet adenosine diphosphate (ADP) P2Y12 receptor. Leptin is the obesity gene product, and its serum level increases with obesity.
Ali Dogan +5 more
doaj +1 more source
Journal of Interventional Cardiology, 2023 Objectives. To evaluate the relationship between the plasma miR-223 expression level and clopidogrel resistance in acute coronary syndrome (ACS) patients. Methods.
Hang Cheng +9 more
doaj +1 more source
ANTIPLATELET THERAPY RESISTANCE IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION
Рациональная фармакотерапия в кардиологии, 2016 Aim. To evaluate the incidence of acetylsalicylic acid (ASA) and clopidogrel resistance in patients with acute coronary syndrome with ST-segment elevation and to find out possible clinical factors, contributing to this state.Material and methods.
D. H. Ainetdinova +2 more
doaj +1 more source
Aspirin and Clopidogrel Resistance
Hematology, 2007 AbstractAspirin and clopidogrel provide significant clinical benefit in patients with cardiovascular disease. However, given the complexity of platelet activation, it is not surprising that aspirin or clopidogrel prevent a small proportion of cardiovascular events.
Desmond J. Fitzgerald, Andrew O. Maree
openaire +3 more sources
Brain Sciences, 2022 Endovascular interventional is an important treatment method for intracranial aneurysms. However, due to the risk of intracranial thrombosis, prophylactic use of antiplatelet drugs is generally required.
Pengfei Xia, Yimin Huang, Gang Chen
doaj +1 more source
Resistance to aspirin and clopidogrel therapy [PDF]
International Journal of Laboratory Hematology, 2010 SummaryIntroduction: Despite increasing evidence on the roles of aspirin and clopidogrel in decreasing morbidity and mortality from cardiovascular disease, resistance to therapy remains an emerging clinical entity. The aim of this review was to revisit current knowledge of the mechanisms, laboratory evaluation, clinical impact and management of ...
J. Beresian +7 more
openaire +3 more sources
Clopidogrel resistance: What's new?
Archives of Cardiovascular Diseases, 2010 The concept of clopidogrel resistance emerged several years ago. Since then, many studies have been performed to elucidate the mechanisms and potential clinical impact of this biological finding. These studies identified complex mechanisms, including drug-drug interactions, genetic polymorphisms and clinical factors, and showed consistently the ...
Johanne Silvain +2 more
openaire +3 more sources