Results 41 to 50 of about 30,781 (201)

Drug resistance with monitored adherence [PDF]

, 2013
Drug resistance can be defined as the failure of a drug to exert its expected effect on pharmacological biomarkers and is caused by pharmacogenetic, cellular or clinical factors.
Walter, Philipp Niklaus
core   +1 more source

Clopidogrel Resistance

American Journal of Therapeutics, 2010
Clopidogrel resistance is an emerging clinical scenario, as antiplatelet therapy has become the cornerstone of modern cardiovascular treatment. This leads to an increase in stent thromboses and recurrent ischemic events which add to the health care costs, and increased periprocedural morbidity and mortality.
Jaya Prakash, Sugunaraj, Chandrasekar, Palaniswamy, Dhana Rekha, Selvaraj, Sri Krishna, Chaitanya Arudra, Rishi, Sukhija   +4 more
openaire   +4 more sources

Ticagrelor Use in Indian Patients Undergoing Neuroendovascular Procedures: A Single Center Experience [PDF]

Neurointervention, 2019
Purpose A safe and efficacious antiplatelet drug is needed for patients with clopidogrel resistance who undergo neuroendovascular procedures. Ticagrelor is a new reversibly binding, oral, direct-acting P2Y receptor antagonist with no known resistance. We
Vivek Karan, Devashish Vyas, Vikram Bohra, Vikram Huded   +3 more
doaj   +1 more source

Effect of obesity and serum leptin level on clopidogrel resistance

Türk Kardiyoloji Derneği Arşivi, 2016
Objective: Clopidogrel inhibits platelet aggregation by blockade of platelet adenosine diphosphate (ADP) P2Y12 receptor. Leptin is the obesity gene product, and its serum level increases with obesity.
Ali Dogan, Serkan Kahraman, Emrah Usta, Emrah Ozdemir, Uzay Gormus, Cavlan Ciftci   +5 more
doaj   +1 more source

Resistance to aspirin and clopidogrel therapy [PDF]

International Journal of Laboratory Hematology, 2010
SummaryIntroduction:  Despite increasing evidence on the roles of aspirin and clopidogrel in decreasing morbidity and mortality from cardiovascular disease, resistance to therapy remains an emerging clinical entity. The aim of this review was to revisit current knowledge of the mechanisms, laboratory evaluation, clinical impact and management of ...
K M, Musallam, K, Charafeddine, A, Bitar, M, Khoury, S, Assaad, J, Beresian, S, Alam, A T, Taher   +7 more
openaire   +2 more sources

ANTIPLATELET THERAPY RESISTANCE IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION

Рациональная фармакотерапия в кардиологии, 2016
Aim. To evaluate the incidence of acetylsalicylic acid (ASA) and clopidogrel resistance in patients with acute coronary syndrome with ST-segment elevation and to find out possible clinical factors, contributing to this state.Material and methods.
D. H. Ainetdinova, A. Е. Udovichenko, V. A. Sulimov   +2 more
doaj   +1 more source

Clopidogrel resistance in stroke patients (The CRISP Trial)

, 2021
Objective: To investigate the incidence of clopidogrel resistance in patients with acute ischaemic stroke and to evaluate whether there is an association between clopidogrel resistance and the occurrence of a further cerebrovascular ischaemic event using
Manoj, A, Qazi,, E, Fitzsimmons, PR, O Owojori, Olukolade, Oates, M, Lloyd, J, Lopez, P, Greenhalf, W, Zaidi, Syed AH, Thachil, J, Menezes, B, Cox, P, Sharma, N, Hussain, F, Fletcher, G, Bonnett, LJ   +15 more
core   +1 more source

The Effect of Ticagrelor for Endovascular Intervention of Intracranial Aneurysm Patients with or without Clopidogrel Resistant: A Meta-Analysis

Brain Sciences, 2022
Endovascular interventional is an important treatment method for intracranial aneurysms. However, due to the risk of intracranial thrombosis, prophylactic use of antiplatelet drugs is generally required.
Pengfei Xia, Yimin Huang, Gang Chen
doaj   +1 more source

Clopidogrel resistance - causes, mechanisms, management [PDF]

, 2023
Introducere. Terapia antiagregantă, prin utilizarea unei game variate de preparate antiagregante, constituie o opțiune de bază în tratamentul patologiilor cardiovasculare.
Vasilache, Eugenia, Guțu, Ina, Caracaș, Anastasia, Latus, Svetlana   +3 more
core  

Diabetes mellitus and clopidogrel “resistance”

Clinical Management Issues, 2015
In our Department arrives a 75-year-old patient with hypertension, diabetes mellitus (DM) treated with hypoglycaemic drugs, dyslipidaemia and ischaemic heart disease post-acute myocardial infarction treated with triple coronary artery bypass surgery and subsequent percutaneous transluminal coronary angioplasty (PTCA).
Massarelli, Laura, Musumeci, Giuseppe, Bussolino, Carlo, Tomaselli, Valerio   +3 more
openaire   +5 more sources