Results 21 to 30 of about 30,781 (201)
Aspirin and clopidogrel resistance: methodological challenges and opportunities
Vascular Health and Risk Management, 2010 Armen Yuri GasparyanClinical Research Unit, Russell’s Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, West Midlands, UKAbstract: Antiplatelet drug resistance is one of the urgent issues in current cardiovascular medicine.
Armen Yuri Gasparyan
doaj +1 more source
Frontiers in Genetics, 2020 In recent years, the relationship between Cyp2C19*2 gene polymorphism and clopidogrel resistance reflected by platelet function assay has been studied extensively, but there is no clear conclusion yet.
Ying Sun +4 more
doaj +3 more sources
Clopidogrel resistance and genetic factors
Türk Kardiyoloji Derneği Arşivi, 2013 Dual antiplatelet therapy combining aspirin and clopidogrel is the standart care for patients WHO ave ACS or undergoing PCI according to guidelines.Itss well established that the antiplatelet response to clopidogrel varies widely among patients.Patients ...
Alev Arat Özkan
doaj +3 more sources
Low-Dose Prasugrel in Patients with Resistance to Clopidogrel for the Treatment of Cerebral Aneurysms [PDF]
Neurointervention, 2018 Thromboembolism is one of the major complications of stent assisted coiling in treatment of cerebral aneurysm. Clopidogrel resistance is so common and prasugrel is more effective in its rapid and potent effect.
Dongwhane Lee +4 more
doaj +2 more sources
Рациональная фармакотерапия в кардиологии, 2016 Platelets play an important role in the pathogenesis of atherosclerosis. They are involved in atherosclerosis progression and thrombotic complications. That is why antiplatelet therapy is a necessary element of these complications prevention in patients ...
A. N. Meshkov
doaj +3 more sources
Brazilian Journal of Cardiovascular SurgeryObjective: The aims of this study were to determine whether the detection of preoperative clopidogrel resistance in patients undergoing cardiac surgery while using clopidogrel could play a guiding role in the prediction of postoperative excessive ...
Mehmet Kizilay +5 more
doaj +2 more sources
Ilaprazole and Clopidogrel Resistance in Acute Stroke Patients. [PDF]
Biomedicines, 2022 Clopidogrel, an antiplatelet agent used for secondary prevention of cerebrovascular diseases, is often taken with proton pump inhibitors (PPIs). Generally, the combined use of clopidogrel and PPIs causes adverse drug–drug interactions.
Lim IH, Lee SJ, Shin BS, Kang HG.
europepmc +2 more sources
Catheterization and Cardiovascular Interventions, 2004 Although platelets lack nuclei and are the smallest circulating human cells, they play an integral and complex role in the process of thrombosis, both physiological and pathophysiological. Activation and aggregation of platelets play a central role in the propagation of intracoronary thrombi after (1) spontaneous atherosclerotic plaque disruption that ...
Stan, Heptinstall +4 more
+7 more sources
The Role of Genetic Polymorphism and Other Factors on Clopidogrel Resistance (CR) in an Asian Population with Coronary Heart Disease (CHD) [PDF]
Molecules, 2021 Mohammed Ahmed Akkaif +2 more
exaly +2 more sources
Aspirin and Clopidogrel Resistance [PDF]
Mayo Clinic Proceedings, 2006 Despite aspirin's and clopidogrel's proven benefit in reducing cardiovascular (CV) events, recurrent CV events still occur in patients receiving antiplatelet therapy. Many of these patients are resistant or only partially responsive to the antiplatelet effects of aspirin and clopidogrel, as determined by standard platelet assays.
Erin D, Michos +4 more
openaire +4 more sources