Results 61 to 70 of about 83,682 (305)
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Genetic Modifiers of Parkinson's Disease: A Case–Control Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik +15 more
wiley +1 more source
The Astrophysical JournalData Release 3 (DR3) from the Gaia Mission includes radial velocity measurements of over 33 million targets. Among many scientific applications, the overlap of this stellar sample with targeted exoplanet transit survey stars presents an opportunity to ...
Quadry Chance +5 more
doaj +1 more source
Characteristics of Cerebral Palsy in the Midwestern US
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim +6 more
wiley +1 more source
On the Anticorrelation between Duration and Redshift in Gamma-Ray Bursts
The Astrophysical Journal, 2023 For gamma-ray bursts (GRBs) with durations greater than two seconds (so-called long GRBs), the intrinsic prompt gamma-ray emission appears, on average, to last longer for bursts at lower redshifts.
Nicole Lloyd-Ronning +6 more
doaj +1 more source
Analysis of Soluble Interleukin‐2 Receptor as a Prognostic Biomarker in NMOSD and MOGAD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Soluble interleukin‐2 receptor (sIL‐2R) is a biomarker for T cell activity. T cells are involved in neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) pathogenesis. However, sIL‐2R has so far not been evaluated in these conditions.
Philipp Klyscz +8 more
wiley +1 more source
The Astrophysical JournalCY Ari and IK Lyn are two eclipsing binary systems that share the same spectral type but exhibit significantly different metallicities. Based on the Wilson–Devinney (W-D) method, the first photometric solutions are obtained by analyzing the new complete ...
Hu-Shan Xu +5 more
doaj +1 more source
PHOTOMETRICAL STUDY OF OVERCONTACT BINARY SYSTEM V859Cyg
Odessa Astronomical Publications, 2016 Wepresent the results of photometrical research of close binary system V859Cyg with possible period variations. The light curve of the star was constructed using V-band magnitudes, obtainedin 2007, 2009, 2014 years in Kalinenkov Astronomical Observatory
E. A. Panko +3 more
doaj +1 more source
The Astrophysical Journal Supplement Series, 2023 Galactic short-period close white dwarf binaries (CWDBs) are important objects for space-borne gravitational-wave (GW) detectors in the millihertz frequency bands.
Liangliang Ren +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source