Results 81 to 90 of about 6,007 (287)

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Carbon Stars from Gaia Data Release 3 and the Space Density of Dwarf Carbon Stars

The Astrophysical Journal
Carbon stars (with atmospheric C/O > 1) range widely in temperature and luminosity, from low-mass dwarfs to asymptotic giant branch (AGB) stars. The main-sequence dwarf carbon (dC) stars have inherited carbon-rich material from an AGB companion, which ...
Benjamin R. Roulston, Naunet Leonhardes-Barboza, Paul J. Green, Evan Portnoi   +3 more
doaj   +1 more source

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

Advanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani, Aditi Singh, Behnam Ashrafi   +2 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Early Planet Formation in Embedded Disks (eDisk). XIII. Aligned Disks with Nonsettled Dust around the Newly Resolved Class 0 Protobinary R CrA IRAS 32

The Astrophysical Journal
Young protostellar binary systems, with expected ages less than ∼10 ^5 yr, are little modified since birth, providing key clues to binary formation and evolution. We present a first look at the young, Class 0 binary protostellar system R CrA IRAS 32 from
Frankie J. Encalada, Leslie W. Looney, Shigehisa Takakuwa, John J. Tobin, Nagayoshi Ohashi, Jes K. Jørgensen, Zhi-Yun Li, Yuri Aikawa, Yusuke Aso, Patrick M. Koch, Woojin Kwon, Shih-Ping Lai, Chang Won Lee, Zhe-Yu Daniel Lin, Alejandro Santamaría-Miranda, Itziar de Gregorio-Monsalvo, Nguyen Thi Phuong, Adele Plunkett, Jinshi Sai (Insa Choi), Rajeeb Sharma, Hsi-Wei Yen, Ilseung Han   +21 more
doaj   +1 more source

Development of Ternary Magnesium Alloys for Laser Powder Bed Fusion: Optimizing Oxide Layer Thickness

Advanced Engineering Materials, EarlyView.
Additive manufacturing of magnesium alloys by laser is difficult because the melting point of the oxide layer is much higher than the evaporation temperature of the metal underneath. Making the oxide layer thinner can solve this problem. Alloying magnesium with strontium makes the oxide layer thinner, especially at 0.5 wt%.
Elmar Jonas Breitbach, Stefan Julmi, Sabine Behrens, Tatiana Blank, Arvid Abel, Nicole Emminghaus, Ludger Overmeyer, Christian Klose, Hans Jürgen Maier   +8 more
wiley   +1 more source

A Novel Approach to Produce Metal–Metal Composites by Leveraging Immiscibility: Laser Powder Bed Fusion of Nanosilver‐Dispersed Titanium

Advanced Engineering Materials, EarlyView.
Incorporating nanosized silver into titanium for antimicrobial materials exploits the metastable miscibility gap between silver and titanium. Silver nanoparticles are synthesized via pulsed laser ablation in liquid. Silver addition refines the microstructure, increases hardness by 30%, and reduces Staphylococcus capitis microbial adhesion by 70%, with ...
Hamed Shokri, Silja‐Katharina Rittinghaus, Janett Schmelzer, Jessica Bertrand, Bilal Gökce   +4 more
wiley   +1 more source

Trans‐Conductive Melt Pool Scaling and its Implications for Parameter Transfer in Laser Powder Bed Fusion for Metals with High Thermal Diffusivity

Advanced Engineering Materials, EarlyView.
Developing process parameters for the laser‐based Powder Bed Fusion of metals can be a tedious task. Based on melt pool depth, the process parameters are transferable to different laser scan speeds. For this, understanding the melt pool scaling behavior is essential, particularly for materials with high thermal diffusivity, as a change in scaling ...
Markus Döring, Matthias Gehring, Michael Schmidt   +2 more
wiley   +1 more source

A Brown Dwarf Orbiting around the Planetary-nebula Central Binary KV Vel

The Astrophysical Journal
KV Vel is a noneclipsing short-period ( P = 0.3571 days) close binary containing a very hot subdwarf primary (77,000 K) and a cool low-mass secondary star (3400 K) that is located at the center of the planetary nebula DS 1.
S.-B. Qian, L.-Y. Zhu, F.-X. Li, L.-J. Li, Z.-T. Han, J.-J. He, L. Zang, L.-F. Chang, Q.-B. Sun, M.-Y. Li, H.-T. Zhang, F.-Z. Yan   +11 more
doaj   +1 more source

Low‐Activation Compositionally Complex Alloys for Advanced Nuclear Applications—A Review

Advanced Engineering Materials, EarlyView.
Low‐activation compositionally complex alloys (LACCAs) are advanced metallic materials primarily composed of low‐activation elements, offering advantages such as rapid compliance with operational standards and safe recyclability. This review highlights their potential for extreme high‐temperature irradiation environments as structural materials for ...
Yangfan Wang, Hanliang Zhu, Zhiyang Wang, Zhijun Qiu, Xiao Wang, Zengxi Pan, Hongtao Zhu, Mingxing Zhang, Huijun Li   +8 more
wiley   +1 more source