Results 71 to 80 of about 906,185 (256)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Accuracy of closed-loop and open-loop propofol delivery systems by bispectral index monitoring in breast surgery patients: a prospective randomized trial

Brazilian Journal of Anesthesiology
Background: This randomized and controlled prospective study tested the hypothesis that closed-loop Target-Controlled Infusion (TCI) of propofol would be associated with better system performance when compared with open-loop controlled delivery of ...
Tian Xie, Yong Wang, Yuhua Liu, Junjie Li, Weijing Li, Hongmeng Xu   +5 more
doaj   +1 more source

Closed-loop, open-source electrophysiology

Frontiers in Neuroscience, 2010
Multiple extracellular microelectrodes (multi-electrode arrays, or MEAs) effectively record rapidly varying neural signals, and can also be used for electrical stimulation.
John D Rolston, John D Rolston, Robert E Gross, Steve M Potter   +3 more
doaj   +1 more source

Closed-loop identification revisited

Automatica, 1999
The paper deals with the identification of multiple-input multiple-output (MIMO) systems operating in closed loop under, in general, linear, time-invariant feedback. The leading idea in the paper is to provide a unified framework for the prediction error methods.
Urban Forssell, Lennart Ljung
openaire   +2 more sources

Optimal Controller and Filter Realisations using Finite-precision, Floating- point Arithmetic. [PDF]

, 2005
The problem of reducing the fragility of digital controllers and filters implemented using finite-precision, floating-point arithmetic is considered.
Whidborne, James F., Wu, Jun, Chen, Sheng, Gu, Da-Wei, Whidborne, J.F., Wu, J., Gu, D.-W., Chen, S.   +7 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Lower plasma insulin levels during overnight closed-loop in school children with type 1 diabetes: Potential advantage? A randomized cross-over trial.

PLoS ONE, 2019
BackgroundStudies have shown that overnight closed-loop insulin delivery can improve glucose control and reduce the risk of hypoglycemia and hence may improve metabolic outcomes and reduce burden for children with type 1 diabetes and their families ...
Ulrike Schierloh, Malgorzata E Wilinska, Ineke M Pit-Ten Cate, Petra Baumann, Roman Hovorka, Carine De Beaufort, Spidiman Study Group: Single Port Insulin Infusion for Improved Diabetes Management   +6 more
doaj   +1 more source

Colour-Kinematics Duality for One-Loop Rational Amplitudes [PDF]

, 2013
Colour-kinematics duality is the conjecture of a group theory-like structure for the kinematic dependence of scattering amplitudes in gauge theory and gravity.
H. Boels, Rutger, O'Connell, Donal; id_orcid, Boels, Rutger Herman, Sven Isermann, Reinke, Isermann, Reinke Sven, O'Connell, Donal Francis, Marmiroli, Daniele, Monteiro, Ricardo   +7 more
core   +1 more source