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The analysis of the epidemic status and risk factors associated with different genotypes Clostridioides difficile mixed infection [PDF]
Background Clostridioides difficile is the main pathogen of antibiotic-associated diarrhea and pseudomembranous enteritis. Mixed Clostridioides difficile infection are simultaneous infection of the same host with strains of different genotypes. In recent
Yulian Zhang +7 more
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Current and future approaches in Clostridioides Difficile management [PDF]
Clostridioides Difficile is considered one of the main causes of the healthcare associated infections worldwide and the main cause of antibiotic-associated diarrhea, with forms of clinical disease ranging from mild to deadly.
George Sebastian Gherlan
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Risk factors for further recurrences of Clostridioides difficile infection at the first and second recurrence: a retrospective cohort [PDF]
Background Recurrent Clostridioides difficile infection is most effectively treated with faecal microbiota transplantation. Swedish and European guidelines suggest faecal microbiota transplantation after a first or second recurrence, respectively.
Måns Stefansson +5 more
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Infective Endocarditis by Clostridioides and Clostridium Species—A Narrative Review
Bacteria of the genus Clostridium are anaerobic Gram-positive spore-forming bacilli that include more than 200 species. Some of them are known to cause invasive infections and diseases caused by the production of toxins.
Petros Ioannou +4 more
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Clostridioides difficile is a Gram positive spore-forming rod and mainly responsible for nosocomial diarrhea in developed nations. Molecular and antimicrobial surveillance is important for monitoring the strain composition including genotypes of high ...
Ahmed Mohamed Mostafa Abdrabou +9 more
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The immunological response against Clostridioides difficile (C. difficile) is crucial for an improved understanding of disease mechanisms and the development of novel therapeutic strategies.
Sophie Roth +10 more
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Recently, the recommendations for the treatment of Clostridioides difficile infection (CDI) have been updated. However, in addition to the clinical efficacy data, the drug of choice should ideally represent optimal antimicrobial stewardship, with an ...
Marcela Krutova, Mark Wilcox, Ed Kuijper
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BackgroundClostridioides difficile is a major cause of healthcare-associated and community-acquired diarrhea. Host genetic susceptibility to Clostridioides difficile infection has not been studied on a large-scale.MethodsA total of 1,160 Clostridioides ...
Jiang Li +11 more
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Non–C. difficile Clostridioides Bacteremia in Intensive Care Patients, France
Usually responsible for soft tissue infections, Clostridioides species can also cause bacteremia, life-threatening infections often requiring intensive care unit (ICU) admission.
Guillaume Morel +21 more
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Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L. +13 more
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