Results 41 to 50 of about 28,268 (242)
Laboratory diagnostic methods for Clostridioides difficile infection [PDF]
, 2023 Introduction. Clostridioides difficile is an anaerobic gram-positive, sporeforming, toxin-producing bacillus that is transmitted among humans through the fecal-oral route, as a result of ingestion of spores. Colonization of C. difficile is prevented by
Alexandrov, Anastasia
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Clostridioides difficile infections: Preventive strategies [PDF]
, 2023 Clostridioides difficile infections primarily affect elderly, hospitalised patients treated with antibiotics and are among the most common healthcare-related infections. This thesis aimed to improve the understanding of the best prevention strategies for
Edman Wallér, Jon
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Microbiology SpectrumThis study aims to compare the sensitivity and specificity of two Nucleic Acid Amplification Tests (NAATs), the STANDARD M10 Clostridioides difficile (M10) and the Xpert C. difficile (Xpert) assays, for the detection of toxigenic C.
Y. Roukoz-Diab +7 more
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Pathogenicity and virulence of Clostridioides difficile
Virulence, 2023 Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarrhea, and is responsible for a spectrum of diseases characterized by high levels of recurrence, morbidity, and mortality. Treatment is complex, since antibiotics constitute both the main treatment and the major risk factor for infection.
Jessica E. Buddle, Robert P. Fagan
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Microbiology SpectrumCurrent guidelines recommend the use of a two-step algorithm for the laboratory diagnosis of Clostridioides difficile infection (CDI). Several commercial rapid immunoassays that detect both GDH and toxin A/B in stool samples are available and could be ...
Hannes Bjarki Vigfússon +3 more
doaj +1 more source
mSphere, 2021 A gold standard diagnostic for Clostridioides ...
Skye R. S. Fishbein +10 more
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, 2023 Sandhya Nagarakanti, Robert Orenstein Division of Infectious Diseases, Mayo Clinic Arizona, Phoenix, AZ, USACorrespondence: Sandhya Nagarakanti, Mayo Clinic Arizona, Division of Infectious Diseases, 577 East Mayo Boulevard, Phoenix, AZ, 85054, USA, Tel ...
Nagarakanti S, Orenstein R
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Iron Regulation in Clostridioides difficile [PDF]
Frontiers in Microbiology, 2018 The response to iron limitation of several bacteria is regulated by the ferric uptake regulator (Fur). The Fur-regulated transcriptional, translational and metabolic networks of the Gram-positive, pathogen Clostridioides difficile were investigated by a combined RNA sequencing, proteomic, metabolomic and electron microscopy approach.
Mareike Berges +17 more
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Clostridioides difficile, a New “Superbug”
Microorganisms, 2023 Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacterium. The clinical features of C. difficile infections (CDIs) can vary, ranging from the asymptomatic carriage and mild self-limiting diarrhoea to severe and sometimes fatal pseudomembranous colitis. C.
Rumyana Markovska +3 more
openaire +3 more sources
Advanced Materials, EarlyView.The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena +10 more
wiley +1 more source