Results 41 to 50 of about 25,400 (245)

Biochemical characterization of sporulation-related histidine kinases in Clostridioides difficile [PDF]

, 2022
Histidine kinases are one of the two proteins that constitute a two-component signal transduction system. These systems are used by bacteria, fungi, and several plants to sense the conditions of their environment and alter their behavior to ensure ...
Shukla, Kriti
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Clostridioides difficile infections: Preventive strategies [PDF]

, 2023
Clostridioides difficile infections primarily affect elderly, hospitalised patients treated with antibiotics and are among the most common healthcare-related infections. This thesis aimed to improve the understanding of the best prevention strategies for
Edman Wallér, Jon
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Clostridioides difficile peptidoglycan modifications

Current Opinion in Microbiology, 2022
The cortex and peptidoglycan of Clostridioides difficile have been poorly investigated. This last decade, the interest increased because these two structures are highly modified and these modifications may be involved in antimicrobial resistance. For example, C.
Coullon, Héloïse, Candela, Thomas
openaire   +4 more sources

Faecal microbiota transplantation for first and second episode of Clostridioides difficile infection

, 2023
Faecal microbiota transplantation is an accepted treatment for multiple recurrent Clostridioides difficile infections. 
Ed J Kuijper (9610556), Joffrey van Prehn (14673381), European Study Group for Clostridioides difficile (14691179), European Study Group for Host and Microbiota Interaction (14691180), Fidelma Fitzpatrick (7895483)   +4 more
core   +1 more source

Novel Drivers of Virulence in Clostridioides difficile Identified via Context-Specific Metabolic Network Analysis

mSystems, 2021
Clostridioides difficileC ...
Matthew L. Jenior, Jhansi L. Leslie, Deborah A. Powers, Elizabeth M. Garrett, Kimberly A. Walker, Mary E. Dickenson, William A. Petri, Rita Tamayo, Jason A. Papin   +8 more
doaj   +1 more source

Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

Nature Communications, 2022
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh, In Young Hwang, Hui Ling Lee, Ryan De Sotto, Jonathan Wei Jie Lee, Yung Seng Lee, John C. March, Matthew Wook Chang   +7 more
doaj   +1 more source

Rare Clinical Association between Clostridioides difficile Infection and Ischemic Colitis: Case Report and Literature Review

Medicina, 2021
Background and Objectives: Gut microbiota plays an important role in the wellbeing of the host through different interactions between microflora constituents. In certain instances, Clostridioides difficile may pullulate, causing infection with associated
Elena Mirela Ionescu, Ana-Maria Curte, Andrei Ovidiu Olteanu, Carmen Monica Preda, Ioana Tieranu, Artsiom Klimko, Cristian George Tieranu   +6 more
doaj   +1 more source

Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection

, 2023
Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical efficacy are incompletely understood.
Seekatz, Anna M., Karen Wong, Tanya M. Monaghan, Dina Kao, Abbas Yadegar, Wong, Karen, Laura Cook, Walter, Jens, Ali Nabavi-Rad, Anna M. Seekatz, Kao, Dina, Monaghan, Tanya M., Cook, Laura, Jens Walter, Nabavi-Rad, Ali, Ibrahim, Fathima F., Pakpoor, Sepideh F., Sepideh Pakpoor, Fathima F. Ibrahim, Yadegar, Abbas   +19 more
core   +1 more source

A Portable Colorimetric Device for Rapid Bacterial Detection with Cleavable Functional Nucleic Acid Probes for A Common Bacterial Endoribonuclease

Angewandte Chemie, EarlyView.
A simple, rapid, and portable gold‐coated filter tip‐based assay (GFTA) is developed for bacterial detection. The GFTA leverages cleavable functional nucleic acid probes as molecular recognition elements to target RNase H2, a highly conserved bacterial endoribonuclease, enabling sensitive and specific colorimetric detection of bacterial pathogens ...
Jiuxing Li, Rudi Liu, Wenqing Zhang, Bruno J. Salena, Yingfu Li   +4 more
wiley   +2 more sources

Laboratory diagnostic methods for Clostridioides difficile infection [PDF]

, 2023
Introduction. Clostridioides difficile is an anaerobic gram-positive, sporeforming, toxin-producing bacillus that is transmitted among humans through the fecal-oral route, as a result of ingestion of spores. Colonization of C. difficile is prevented by
Alexandrov, Anastasia
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