Results 51 to 60 of about 25,400 (245)
Clostridioides difficile epidemiology in India
Anaerobe, 2022 Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community populations worldwide. In contrast to the substantial resources invested in the diagnosis and prevention of CDI in high-income countries, this anaerobic toxigenic bacterium has been largely overlooked in low-and-middle-income countries (LMICs) such as India,
Tanya M. Monaghan +4 more
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Pathogenicity and virulence of Clostridioides difficile
Virulence, 2023 Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarrhea, and is responsible for a spectrum of diseases characterized by high levels of recurrence, morbidity, and mortality. Treatment is complex, since antibiotics constitute both the main treatment and the major risk factor for infection.
Jessica E. Buddle, Robert P. Fagan
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Iron Regulation in Clostridioides difficile [PDF]
Frontiers in Microbiology, 2018 The response to iron limitation of several bacteria is regulated by the ferric uptake regulator (Fur). The Fur-regulated transcriptional, translational and metabolic networks of the Gram-positive, pathogen Clostridioides difficile were investigated by a combined RNA sequencing, proteomic, metabolomic and electron microscopy approach.
Mareike Berges +17 more
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Clostridioides difficile Infection [PDF]
Annals of Internal Medicine, 2018 Clostridioides difficile (formerly Clostridium difficile) infection is the most frequently identified health care-associated infection in the United States. C difficile has also emerged as a cause of community-associated diarrhea, resulting in increased incidence of community-associated infection.
Alice Y, Guh, Preeta K, Kutty
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mSphere, 2021 A gold standard diagnostic for Clostridioides ...
Skye R. S. Fishbein +10 more
doaj +1 more source
Clostridioides difficile Flagella
International Journal of Molecular SciencesClostridioides difficile is an important pathogen for humans with a lead in nosocomial infection, but it is also more and more common in communities. Our knowledge of the pathology has historically been focused on the toxins produced by the bacteria that remain its major virulence factors.
Jean-Christophe Marvaud +3 more
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Microbiology SpectrumCurrent guidelines recommend the use of a two-step algorithm for the laboratory diagnosis of Clostridioides difficile infection (CDI). Several commercial rapid immunoassays that detect both GDH and toxin A/B in stool samples are available and could be ...
Hannes Bjarki Vigfússon +3 more
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Clostridioides difficile, a New “Superbug”
Microorganisms, 2023 Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacterium. The clinical features of C. difficile infections (CDIs) can vary, ranging from the asymptomatic carriage and mild self-limiting diarrhoea to severe and sometimes fatal pseudomembranous colitis. C.
Rumyana Markovska +3 more
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Clostridioides difficile Infection: A Never-Ending Challenge
, 2022 The most common worldwide cause of antibiotic-associated diarrhea/colitis is the toxin-producing bacterium Clostridioides difficile [...
Petrosillo, Nicola, Nicola Petrosillo
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Epidemiologia da Infeção por Clostridioides difficile em Portugal: um Estudo Retrospetivo, Observacional em Doentes Hospitalizados [PDF]
, 2022 Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among ...
Moreira, Hugo +29 more
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