Results 31 to 40 of about 28,268 (242)

Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection [PDF]

, 2023
Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical efficacy are incompletely understood.
Seekatz, Anna M., Karen Wong, Tanya M. Monaghan, Dina Kao, Abbas Yadegar, Wong, Karen, Laura Cook, Walter, Jens, Ali Nabavi-Rad, Anna M. Seekatz, Kao, Dina, Monaghan, Tanya M., Cook, Laura, Jens Walter, Nabavi-Rad, Ali, Ibrahim, Fathima F., Pakpoor, Sepideh F., Sepideh Pakpoor, Fathima F. Ibrahim, Yadegar, Abbas   +19 more
core   +1 more source

European Society of Clinical Microbiology and Infectious Diseases:2021 update on the treatment guidance document for Clostridioides difficile infection in adults [PDF]

, 2021
SCOPE: In 2009, the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) published the first treatment guidance document for Clostridioides difficile infection (CDI). This document was updated in 2014.
Guery, B., Wilcox, M.H., Hristea, A, Goorhuis, A, Tschudin-Sutter, S, Kuijper, E J, Coia, J; id_orcid, Bouza, E, van Rossen, T.M., Wilcox, M H, Allerberger, F, Vehreschild, M, Bouza, E., van Rossen, T M, Reigadas, E, van Prehn, J, Scharvik Olesen, B R, Norén, T., Allerberger, F., Ooijevaar, R.E., Scharvik Olesen, B.R., Burns, K, Ooijevaar, R E, van Prehn, J., Burns, K., Tschudin-Sutter, S., Krutova, M, Vogelzang, E.H., Hristea, A., Goorhuis, A., Fitzpatrick, F., Coia, J.E., Guery, B, Vehreschild, MJGT, Norén, T, Fitzpatrick, F, Krutova, M., Vogelzang, E H, Reigadas, E., Kuijper, E.J.   +39 more
core   +1 more source

Does Fecal Microbiota Transplant Have a Role in Treating Recurrent Clostridioides difficile Infection in Rural Hospitals?

Frontiers in Public Health, 2021
Clostridioides difficile infection possesses a significant economical burden, specifically in the inpatient and rural settings. Fecal Microbiota Transplant has been used for treatment of recurrent Clostridioides difficile but its utility is limited by ...
Krishna Vedala, Philip Sobash, Parth Shah, Gilbert-Roy Kamoga   +3 more
doaj   +1 more source

Biochemical characterization of sporulation-related histidine kinases in Clostridioides difficile [PDF]

, 2022
Histidine kinases are one of the two proteins that constitute a two-component signal transduction system. These systems are used by bacteria, fungi, and several plants to sense the conditions of their environment and alter their behavior to ensure ...
Shukla, Kriti
core  

Clostridioides difficile peptidoglycan modifications

Current Opinion in Microbiology, 2022
The cortex and peptidoglycan of Clostridioides difficile have been poorly investigated. This last decade, the interest increased because these two structures are highly modified and these modifications may be involved in antimicrobial resistance. For example, C.
Coullon, Héloïse, Candela, Thomas
openaire   +4 more sources

Novel Drivers of Virulence in Clostridioides difficile Identified via Context-Specific Metabolic Network Analysis

mSystems, 2021
Clostridioides difficileC ...
Matthew L. Jenior, Jhansi L. Leslie, Deborah A. Powers, Elizabeth M. Garrett, Kimberly A. Walker, Mary E. Dickenson, William A. Petri, Rita Tamayo, Jason A. Papin   +8 more
doaj   +1 more source

Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

Nature Communications, 2022
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh, In Young Hwang, Hui Ling Lee, Ryan De Sotto, Jonathan Wei Jie Lee, Yung Seng Lee, John C. March, Matthew Wook Chang   +7 more
doaj   +1 more source

Rare Clinical Association between Clostridioides difficile Infection and Ischemic Colitis: Case Report and Literature Review

Medicina, 2021
Background and Objectives: Gut microbiota plays an important role in the wellbeing of the host through different interactions between microflora constituents. In certain instances, Clostridioides difficile may pullulate, causing infection with associated
Elena Mirela Ionescu, Ana-Maria Curte, Andrei Ovidiu Olteanu, Carmen Monica Preda, Ioana Tieranu, Artsiom Klimko, Cristian George Tieranu   +6 more
doaj   +1 more source

Impact of COVID-19 pandemic on prevalence of Clostridioides difficile infection in a UK tertiary centre [PDF]

, 2022
Serious concerns have been raised about a possible increase in cases of Clostridioides difficile infection (CDI) during the COVID-19 pandemic. We conducted a retrospective observational single centre study which revealed that total combined community and
Hills, Tim, Crooks, Colin, Twitchell, Hannah, Clarkson, Annette, Montgomery, Ros, Monaghan, Tanya M., Abdic, Heather, Briggs, Steve, Voona, Sanjana   +8 more
core   +1 more source

Clostridioides difficile epidemiology in India

Anaerobe, 2022
Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community populations worldwide. In contrast to the substantial resources invested in the diagnosis and prevention of CDI in high-income countries, this anaerobic toxigenic bacterium has been largely overlooked in low-and-middle-income countries (LMICs) such as India,
Tanya M. Monaghan, Rima Biswas, Ashish Satav, Shrikant Ambalkar, Rajpal Singh Kashyap   +4 more
openaire   +2 more sources