Results 61 to 70 of about 28,268 (242)

Clostridioides difficile Infection: A Never-Ending Challenge

, 2022
The most common worldwide cause of antibiotic-associated diarrhea/colitis is the toxin-producing bacterium Clostridioides difficile [...
Petrosillo, Nicola, Nicola Petrosillo
core   +1 more source

5,6-Fused Heterocycle Cholate Derivatives as Spore Germination Inhibitors of Clostridioides difficile [PDF]

, 2023
Clostridioides difficile infection (CDI) is an anaerobic bacterium that is responsible for most antibiotic-associated cases of diarrhea. CDI begins with the ingestion of an environmentally stable spore that germinates within the GI tract under specific ...
Shiv, Sharma, Ernesto, Abel-Santos, Jacqueline, Phan, Steven, Firestine   +3 more
core   +1 more source

Impact of Postoperative Infectious Complications on Long‐Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era

Annals of Gastroenterological Surgery, EarlyView.
Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto, Ryosuke Mizuno, Yoshiro Itatani, Tetsuya Shiota, Masahiro Yamada, Tadayoshi Yamaura, Mami Yoshitomi, Kazutaka Obama   +7 more
wiley   +1 more source

Identification of a Novel Regulator of Clostridioides difficile Cortex Formation

mSphere, 2021
The Centers for Disease Control has designated Clostridioides difficileC.
Megan H. Touchette, Hector Benito de la Puebla, Carolina Alves Feliciano, Benjamin Tanenbaum, Monica Schenone, Steven A. Carr, Aimee Shen   +6 more
doaj   +1 more source

Diagnosis of bacteraemia in neonatal foals using 16S rRNA high‐throughput sequencing

Equine Veterinary Journal, EarlyView.
Abstract Background Sepsis is an important cause of morbidity and mortality in foals. Early diagnosis can improve outcome but is complicated by non‐specific clinical signs and delayed confirmation of infection via blood culture. Molecular assays represent a rapid and more sensitive alternative.
Flavie Payette, Alicia E. Long, Weiming Hu, Kyle Bittinger, Ahmed M. Moustafa, Darko Stefanovski, Michelle Abraham, Maia R. Aitken   +7 more
wiley   +1 more source

Knowledge and experiences of nurses/technicians about Clostridioides difficile infection

, 2023
Ovaj završni rad istražuje znanja i iskustva medicinskih sestara/tehničara o infekciji Clostridioides difficile. Clostridioides difficile infekcija predstavlja izazov za zdravstveni sustav i zahtijeva pažljivo upravljanje radi prevencije širenja ...
Rendulić, Barbara
core   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Newer Therapeutics to Selectively Kill Clostridioides difficile and Restore the Microbiome

Infectious Disease Reports
Background: The antibiotic ibezapolstat and the live biotherapeutic product live-JSLM are promising future approaches for treating Clostridioides difficile infection.
Guido Granata, Nicola Petrosillo
doaj   +1 more source

An Osmotic Laxative Renders Mice Susceptible to Prolonged Clostridioides difficile Colonization and Hinders Clearance

mSphere, 2021
Diarrheal samples from patients taking laxatives are typically rejected for Clostridioides difficileC ...
Sarah Tomkovich, Ana Taylor, Jacob King, Joanna Colovas, Lucas Bishop, Kathryn McBride, Sonya Royzenblat, Nicholas A. Lesniak, Ingrid L. Bergin, Patrick D. Schloss   +9 more
doaj   +1 more source

National trends in pathogen‐specific diagnoses and outcomes among hospitalizations for infectious diarrhea

Journal of Hospital Medicine, EarlyView.
Abstract Background The diagnostic evaluation of infectious diarrhea has evolved with increasing adoption of multiplex gastrointestinal nucleic acid amplification tests and changing diagnostic strategies for Clostridioides difficile. Objectives We aimed to assess changes in inpatient pathogen‐specific documentation rates and clinical outcomes on a ...
David Wong Arias, Spencer R. Goble, Mauricio Torrealba   +2 more
wiley   +1 more source