Results 151 to 160 of about 40,986 (311)

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

open access: yesNeurogastroenterology &Motility, EarlyView.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source

Treatment of Clostridioides Difficile with Fecal Microbiota Transplantation [PDF]

open access: yes, 2020
Research was performed to discuss the epidemiology and current guidelines of Clostridioides difficile infection (CDI), recurrent C. difficile infection (rCDI), the different modalities of fecal microbiota transplantation (FMT), the donor screening ...
Green, Brenton
core   +2 more sources

Photodynamic therapy of cancer‐associated infections

open access: yesPhotochemistry and Photobiology, EarlyView.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

Antibiotic Exposure and Risk of Allograft Rejection and Survival After Liver Transplant: An Observational Cohort Study From a Tertiary Referral Centre

open access: yesTransplant Infectious Disease, EarlyView.
Because the relationship between the gut microbiota and liver transplant outcomes is not well described, it is possible that there are, as yet, unrecognized negative impacts of antibiotic exposures on key liver transplant‐related outcomes. We observed a negative association between antibiotic exposures, particularly those with an anaerobic spectrum of ...
Olivia C. Smibert   +11 more
wiley   +1 more source

Interaction Between Microbiota and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and New Therapeutic Opportunities

open access: yesMedComm, Volume 6, Issue 7, July 2025.
This review systematically concludes the interaction between microbiota and immunity. We introduce six phyla: Bacteroidetes, Firmicutes, Actinobacteria, Proteobacteria, Fusobacteria, and Verrucomicrobia. We also elucidate molecular mechanisms, biological functions, diseases, and new therapeutic opportunities between microbiota and immunity. .
Jingjing Zeng   +4 more
wiley   +1 more source

The Effects of Short Chain Fatty Acids on Clostridioides Difficile Growth, Sporulation, and Toxin Production [PDF]

open access: yes, 2022
Short chain fatty acids (SCFAs) are products of bacterial fermentation that help maintain important gut functions such as the intestinal barrier, signaling, and immune homeostasis.
Baldassare, Michelle
core   +1 more source

A Review of Therapies for Clostridioides difficile Infection

open access: yesAntibiotics
Clostridioides difficile is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of Clostridioides difficile infection (CDI), it remains a ...
Faiza Morado, Neha Nanda
doaj   +1 more source

Probiotics and the Prevention of Clostridioides difficile: A Review of Existing Systematic Reviews [PDF]

open access: yes, 2020
Clostridioides difficile is the leading cause of infectious diarrhea (Vernaya et al., 2017). Probiotics have been proposed to provide a protective benefit against Clostridioides difficile infection (CDI).
Onstad, Andrea L.
core   +1 more source

Real-world Effectiveness of Fecal Microbiota Transplantation for First or Second Clostridioides difficile Infection [PDF]

open access: yes
Background & Aims: Clostridioides difficile infection (CDI) is associated with high mortality. Fecal microbiota transplantation (FMT) is an established treatment for recurrent CDI, but its use for first or second CDI remains experimental. We aimed to
Baumwall, Simon Mark Dahl   +20 more
core   +1 more source

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