Results 151 to 160 of about 40,986 (311)
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley +1 more source
Treatment of Clostridioides Difficile with Fecal Microbiota Transplantation [PDF]
Research was performed to discuss the epidemiology and current guidelines of Clostridioides difficile infection (CDI), recurrent C. difficile infection (rCDI), the different modalities of fecal microbiota transplantation (FMT), the donor screening ...
Green, Brenton
core +2 more sources
Photodynamic therapy of cancer‐associated infections
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley +1 more source
Because the relationship between the gut microbiota and liver transplant outcomes is not well described, it is possible that there are, as yet, unrecognized negative impacts of antibiotic exposures on key liver transplant‐related outcomes. We observed a negative association between antibiotic exposures, particularly those with an anaerobic spectrum of ...
Olivia C. Smibert+11 more
wiley +1 more source
Clostridioides Difficile Infection
Alessandro Fichera, Linda Ferrari
openaire +6 more sources
This review systematically concludes the interaction between microbiota and immunity. We introduce six phyla: Bacteroidetes, Firmicutes, Actinobacteria, Proteobacteria, Fusobacteria, and Verrucomicrobia. We also elucidate molecular mechanisms, biological functions, diseases, and new therapeutic opportunities between microbiota and immunity. .
Jingjing Zeng+4 more
wiley +1 more source
The Effects of Short Chain Fatty Acids on Clostridioides Difficile Growth, Sporulation, and Toxin Production [PDF]
Short chain fatty acids (SCFAs) are products of bacterial fermentation that help maintain important gut functions such as the intestinal barrier, signaling, and immune homeostasis.
Baldassare, Michelle
core +1 more source
A Review of Therapies for Clostridioides difficile Infection
Clostridioides difficile is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of Clostridioides difficile infection (CDI), it remains a ...
Faiza Morado, Neha Nanda
doaj +1 more source
Probiotics and the Prevention of Clostridioides difficile: A Review of Existing Systematic Reviews [PDF]
Clostridioides difficile is the leading cause of infectious diarrhea (Vernaya et al., 2017). Probiotics have been proposed to provide a protective benefit against Clostridioides difficile infection (CDI).
Onstad, Andrea L.
core +1 more source
Real-world Effectiveness of Fecal Microbiota Transplantation for First or Second Clostridioides difficile Infection [PDF]
Background & Aims: Clostridioides difficile infection (CDI) is associated with high mortality. Fecal microbiota transplantation (FMT) is an established treatment for recurrent CDI, but its use for first or second CDI remains experimental. We aimed to
Baumwall, Simon Mark Dahl+20 more
core +1 more source