The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny and Escherichia core genomic diversity [PDF]
EnteroBase is an integrated software environment which supports the identification of global population structures within several bacterial genera that include pathogens.
Achtman, Mark +6 more
core +1 more source
Clostridioides difficile epidemiology in India
Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community populations worldwide. In contrast to the substantial resources invested in the diagnosis and prevention of CDI in high-income countries, this anaerobic toxigenic bacterium has been largely overlooked in low-and-middle-income countries (LMICs) such as India,
Tanya M. Monaghan +4 more
openaire +2 more sources
Developing Gut Microbiota Exerts Colonisation Resistance to Clostridium (syn. Clostridioides) difficile in Piglets [PDF]
Clostridium (syn. Clostridioides) difficile is considered a pioneer colonizer and may cause gut infection in neonatal piglets. The aim of this study was to explore the microbiota-C. difficile associations in pigs.
Dadi, Temesgen Hailemariam +3 more
core +1 more source
Uncovering the Harms of Treating Clostridioides difficile Colonization
Patients with toxin-negative Clostridioides ...
Christopher R. Polage +1 more
doaj +1 more source
Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis [PDF]
Importance: An understanding of the incidence and outcomes of Clostridium difficile infection (CDI) in the United States can inform investments in prevention and treatment interventions.
Balkenende, Erin +15 more
core +1 more source
Antibiotic stewardship implementation and patient-level antibiotic use at hospitals with and without on-site Infectious Disease specialists. [PDF]
Many US hospitals lack Infectious Disease (ID) specialists, which may hinder antibiotic stewardship efforts. We sought to compare patient-level antibiotic exposure at Veterans Health Administration (VHA) hospitals with and without an on-site ID ...
Alexander, Bruce +9 more
core +3 more sources
Cost-Effectiveness Analysis of Bezlotoxumab Added to Standard of Care Versus Standard of Care Alone for the Prevention of Recurrent Clostridium difficile Infection in High-Risk Patients in Spain [PDF]
Introduction Clostridium difficile infection (CDI) is the major cause of infectious nosocomial diarrhoea and is associated with considerable morbidity, mortality and economic impact.
Aceituno, Susana +7 more
core +3 more sources
Clostridioides difficile, a New “Superbug”
Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacterium. The clinical features of C. difficile infections (CDIs) can vary, ranging from the asymptomatic carriage and mild self-limiting diarrhoea to severe and sometimes fatal pseudomembranous colitis. C.
Rumyana Markovska +3 more
openaire +3 more sources
A gold standard diagnostic for Clostridioides ...
Skye R. S. Fishbein +10 more
doaj +1 more source
High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection [PDF]
Objectives: Despite multiple risk factors and a high rate of colonization for Clostridium difficile, the occurrence of C. difficile infection in patients with cystic fibrosis is rare.
Acharya, K. Ravi +7 more
core +2 more sources

