Results 81 to 90 of about 19,913 (173)

An Exploratory Study on the Pathogenic Role of Faecal Extracellular Vesicles in Metabolic Dysfunction‐Associated Steatotic Liver Disease Progression and in Drug‐Induced Liver Injury

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
Fecal extracellular vesicles (fEVs) from DILI patients have a distinct bacterial profile. This study provides evidence that bacterial EVs enter the bloodstream. DILI and MASLD F≥3 fEVs increase the pro‐inflammatory response and hepatocyte steatosis. FEVs from DILI patients enhance the hepatotoxic potential of diclofenac.
Antonio J. Ruiz‐Malagón, Marina Herraiz‐Vilela, Jose Pinazo‐Bandera, Juan Pedro Toro‐Ortiz, Carlos López‐Gómez, Ailec Ho‐Plagaro, Lourdes Garrido‐Sánchez, Mercedes Robles‐Díaz, Bernard Taminiau, Georges Daube, Judith Sanabria‐Cabrera, Gonzalo Matilla‐Cabello, Maria Isabel Lucena, Raúl J. Andrade, Eduardo García‐Fuentes, Miren García‐Cortes, Cristina Rodriguez‐Diaz   +16 more
wiley   +1 more source

Lachnospiraceae‐Derived Extracellular Vesicles Mediate the Cardioprotective Effects of Barley Leaf in Myocardial Infarction by Improving Intestinal Stem Cell Function

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Ischaemic cardiovascular diseases, particularly myocardial infarction (MI), remain the leading causes of morbidity and mortality worldwide. Targeting extracellular vesicles (EVs) from the gut microbiota by diet may provide opportunities to improve cardiovascular health. Barley leaf (BL) has a long history of use in Traditional Chinese medicine
Wenjing Chen, Yifan Zhao, Qian Zhao, Yingzhuo Zhou, Chen Ma, Li Dong, Yinghua Luo, Zhong Zhang, Fang Chen, Xiaosong Hu, Daotong Li   +10 more
wiley   +1 more source

Bacteriophage Therapy: Current Strategies and Future Perspectives

MedComm, Volume 7, Issue 3, March 2026.
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou, Hanyu Fu, Mengzhe Li, Zhongyu Han, Zhenchao Wu, Huahao Fan, Ning Shen, Jiajia Zheng   +7 more
wiley   +1 more source

A Review of Therapies for Clostridioides difficile Infection

Antibiotics
Clostridioides difficile is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of Clostridioides difficile infection (CDI), it remains a ...
Faiza Morado, Neha Nanda
doaj   +1 more source

Concurrent Presentation of von Willebrand Disease and Inflammatory Bowel Disease—A Case Report and Literature Review

eJHaem, Volume 7, Issue 2, April 2026.
Suraj Pratap, Aimee Foord
wiley   +1 more source

Electroelution Into a Salt Trap: Reviving an Old‐School Approach to DNA Purification

Small Methods, Volume 10, Issue 5, 9 March 2026.
Electroelution into a salt cushion is a well‐established yet underutilized method of capturing gel‐purified nucleic acids. This Perspective discusses how this traditional method can be reengineered to meet the demands of next‐generation technologies, such as long‐read sequencing.
Ruslan Kalendar, Konstantin I. Ivanov, Olga V. Samuilova, Timo Burster, Andrey A. Zamyatnin Jr.   +4 more
wiley   +1 more source

Survey on Faecal Microbiota Transplantation and Probiotic Use in Equine Practice in France and Belgium

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
A survey of 96 equine veterinarians in France and Belgium revealed widespread therapeutic use of probiotics (82.1%) and faecal microbiota transplantation (76.0%). Knowledge gaps persisted, with 16.7% misidentifying non‐probiotic products and only 22.5% performing donor testing before FMT.
Clémence Loublier, Bernard Taminiau, Laurence Seidel, Nassim Moula, Colombe Tano, Carla Cesarini, Marcio Costa, Laureline Lecoq, Georges Daube, Hélène Amory   +9 more
wiley   +1 more source

Advance Microbiota Transplantation: A Novel Addition–Subtraction Paradigm for Optimising Faecal Microbiota Transplantation

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
This review proposes Advance Microbiota Transplantation (AMT), a pre‐peri‐post transplant ‘addition–subtraction’ framework that integrates donor–recipient optimisation, product engineering, and post‐transplant recipient adjuvant management to enhance conventional FMT efficacy and mitigate its limitations. ABSTRACT Faecal microbiota transplantation (FMT)
Haojia Lin, Zelin Feng, Qiuyue Tu, Huizhen Li, Yanru Zhang, Xinyue Wei, Qinghua Yi, Hetong Zhang, Yu Wang, Xiaoqin Li, Yueting Li, Jun Huang, Zehan Chen, Hongtian Shentu, Anjiang Wang, Ye Chen, Xiaolong He, Xiaocang Cao   +17 more
wiley   +1 more source

Recommendations for Stress Ulcer Prophylaxis in Critically Ill Adults: A Contextualized Clinical Practice Guideline From the Saudi Critical Care Society and the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Endorsed by the Kuwait Anesthesia and Critical Care Society

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Critically ill adults are at risk for stress‐related upper gastrointestinal bleeding (UGIB). Regional variations in gastrointestinal bleeding incidence, infection epidemiology, formulary access, and the relative value placed on bleeding versus infection outcomes by patients and clinicians necessitate contextualized recommendations ...
Marwa Amer, Waleed Alhazzani, Fayez Alshamsi, Anders Granholm, Yaseen M. Arabi, Klaus T. Olkkola, Marius Rehn, Abdulrahman Al‐Fares, Rakan M. Alqahtani, Ahmed Aljedai, Haifa F. Alotaibi, Amr Arafat, Shadan AlMuhaidib, Ali Al Bshabshe, Ville Jalkanen, Martin Ingi Sigurðsson, Michelle S. Chew, Maija‐Liisa Kalliomäki, Hasan M. Al‐Dorzi, Fawziah Alkhaldi, Haifa Algethamy, Majid A. Almadi, Namareq Aldardeer, Abdullah M. Alhammad, Awad Al‐Omari, Faisal A. Al‐Suwaidan, Mohammed Alshahrani, Morten Hylander Møller   +27 more
wiley   +1 more source

Whole genome sequence analysis reveals limited diversity among Clostridioides difficile ribotype 027 and 078 isolates collected in 22 hospitals in Berlin and Brandenburg, Germany

Antimicrobial Resistance and Infection Control
Background Clostridioides difficile infections (CDI) present significant health risks and are among the most important nosocomial infections. Ribotype (RT) 027 poses a particular risk due to its proposed “hypervirulence”. Traditionally, C.
Esther E. Dirks, Vanessa Pfiffer, Genevieve Sohl, Fabian K. Berger, Ina Friesen, Johannes Friesen, Ralf Ignatius, Johannes Elias, Alexander Mellmann, Mardjan Arvand   +9 more
doaj   +1 more source