Clostridioides difficile infection is currently the leading cause of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis worldwide. Cathelicidins, a major group of natural antimicrobial peptides, have antimicrobial and immunomodulatory
Banglao Xu, Xianan Wu, Yi Gong, Ju Cao
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Clostridioides (formerly Clostridium) difficile infection is a common and costly healthcare-associated infection. Extraintestinal C. difficile infection is rarely encountered, especially in isolation.
Justine Chinnappan +5 more
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Cutting edges in Clostridioides difficile infections
Clostridioides difficile is the most common cause of hospital-acquired diarrhoea and one of the most important causes of hospital-acquired infections.
Ana Durovic, Sarah Tschudin-Sutter
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Bacteriophages Contribute to Shaping Clostridioides (Clostridium) difficile Species. [PDF]
Bacteriophages (phages) are bacterial viruses that parasitize bacteria. They are highly prevalent in nature, with an estimated 1031 viral particles in the whole biosphere, and they outnumber bacteria by at least 10-fold. Hence, phages represent important
Fortier LC.
europepmc +2 more sources
Fecal microbiota transplantation via colonoscopy in a dog with Clostridioides (Clostridium) difficile infection [PDF]
: In dogs, antimicrobial therapy for Clostridioides (Clostridium) difficile infection (CDI) is based solely on metronidazole, leaving limited treatment options in case of recurrent disease.
Amanda Nadia Diniz +6 more
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Clostridioides difficile – a new name, the old problems with diagnosis and treatment
Clostridium difficile was reclassified in 2016 under a new name of Clostridioides difficile. In 2021 to 2022, some changes were implemented into the main clinical guidelines on the diagnosis and treatment of infections caused by this pathogen. A two-step
Sergey M. Zakharenko
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Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores. [PDF]
Clostridium difficile is the leading cause of hospital acquired diarrhoea in industrialised countries. Under conditions that are not favourable for growth, the pathogen produces metabolically dormant endospores via asymmetric cell division.
Fairweather, NF +24 more
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Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults
Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12
Kathryn A Connor, Kelly M Conn
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Comparison of culture and isolation methods for Clostridioides difficile and other anaerobes from stool samples in a routine microbiological laboratory practice [PDF]
Objective. To improve stool sample culture and isolation of anaerobic flora, including Clostridioides difficile in the routine microbiological laboratory practice at the children’s oncology hospital. Materials and Methods.
Shvydkaya M.G. +3 more
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The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains. [PDF]
BACKGROUND: Clostridium difficile is the major cause of antibiotic associated diarrhoea and in recent years its increased prevalence has been linked to the emergence of hypervirulent clones such as the PCR-ribotype 027. Characteristically, C.
McNerney Ruth +23 more
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