Results 101 to 110 of about 44,840 (262)

Knowledge, Attitude, and the Practice in Nosocomial Infection Control Among Afghan Healthcare Workers in Herat Afghanistan: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Hospital‐acquired infections (HIAs) remain a major threat to patient and healthcare worker (HCW) safety globally, with higher burden in low‐resource settings. Despite moderate knowledge among HCWs in many low‐income contexts, actual adherence to infection prevention practices is often poor.
Mohammad Masudi, Enayatollah Ejaz, Mohammad Faisal Wardak, Ali Rahimi, Nasar Ahmad Shayan, Joseph Christian Obnial, Don Eliseo Lucero‐Prisno III   +6 more
wiley   +1 more source

Fecal microbiota transplantation beyond Clostridioides difficile infections [PDF]

eBioMedicine, 2019
The importance of the commensal microbiota to human health and well-being has become increasingly evident over the past decades. From a therapeutic perspective, the popularity of fecal microbiota transplantation (FMT) to restore a disrupted microbiota and amend imbalances has increased.
Wortelboer, Koen, Nieuwdorp, Max, Herrema, Hilde   +2 more
openaire   +5 more sources

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

Archiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová, Šárka Štěpánková, Eva Frýbová, Klára Konečná, Jana Korbielová, Markéta Švarcová, Ondřej Janďourek, Václav Pflégr, Szilvia Bősze, Martin Krátký   +9 more
wiley   +1 more source

Bile Acids as Key Mediators of the Gut Microbiota–Immune Axis: Potential Biomarker and Therapeutic Perspectives

BioFactors, Volume 52, Issue 1, January/February 2026.
Primary bile acids synthesized in the liver are transformed by gut microbes into secondary bile acids that engage receptors such as FXR and TGR5, thereby modulating immune function and metabolic homeostasis. Dysregulation of these signaling pathways contributes to MASH, NAFLD, IBD, and neurodegenerative disorders, underscoring their relevance as ...
Simone Baldi, Margherita Turrini, Francesco Cei, Marta Menicatti, Gianluca Bartolucci, Amedeo Amedei   +5 more
wiley   +1 more source

Clostridioides difficile Infection

Clinics in Colon and Rectal Surgery, 2020
Linda, Ferrari, Alessandro, Fichera
openaire   +5 more sources

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

Frontiers in Cellular and Infection Microbiology
Clostridioides difficile infection (CDI) is a significant cause of antibiotic-associated diarrhea and pseudomembranous colitis, manifesting as mild diarrhea, fulminant colitis, and even death.
Xin Wen, Xue Liu, Kai Wan, Hong Liu, Cheng Zhang, Xi Zhang, Qin Wen   +6 more
doaj   +1 more source

Clostridioides difficile Enteritis Induced Anastomotic Rupture: A Case Report and Literature Review

Case Reports in Surgery, 2020
Background. A 76-year-old male patient who suffered small bowel anastomotic dehiscence believed to be a complication provoked by Clostridioides difficile enteritis. Case Presentation. The patient was a 76-year-old male who underwent small bowel resection
David R. Velez, Mentor Ahmeti
doaj   +1 more source

A Real-World Study on the Clinical Characteristics, Outcomes, and Relationship between Antibiotic Exposure and Clostridioides difficile Infection

Antibiotics
Clostridioides difficile is a Gram-positive bacteria that causes nosocomial infections, significantly impacting public health. In the present study, we aimed to describe the clinical characteristics, outcomes, and relationship between antibiotic exposure
B. Vintilă, A. Arseniu, C. Morgovan, Anca Butuca, V. Bîrluțiu, C. Dobrea, L. Rus, S. Ghibu, A. Bereanu, Rares Arseniu, Ioana Roxana Codru, Mihai Sava, Felicia Gabriela Gligor   +12 more
semanticscholar   +1 more source

Exploring Fecal Microbiota Transplantation: Potential Benefits, Associated Risks, and Challenges in Cancer Treatment

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Fecal microbiota transplantation (FMT) has emerged as a groundbreaking strategy for modulating the gut microbiome and improving cancer treatment outcomes. This review synthesizes the current evidence on the role of FMT in oncology, focusing on its potential to enhance the efficacy of immunotherapy, restore microbiome homeostasis ...
Aswathi Ramesh, Rajasekaran Subbarayan, Rupendra Shrestha, Pooja Narain Adtani   +3 more
wiley   +1 more source

SER-109 (VOWST™): A Review in the Prevention of Recurrent Clostridioides difficile Infection

Drugs
SER-109 (VOWST™; fecal microbiota spores, live-brpk) is a live biotherapeutic product indicated to prevent the recurrence of Clostridioides difficile infection (CDI) in patients 18 years of age and older following standard of care (SOC) antibacterial ...
Hannah A. Blair
semanticscholar   +1 more source