Results 71 to 80 of about 19,142 (210)

Whole microbiota transplantation restores gut homeostasis throughout the gastrointestinal tract

iMeta, Volume 4, Issue 6, December 2025.
This study introduces whole microbiota transplantation (WMT), a synergistic therapeutic approach that concurrently transplants small intestinal and fecal microbiota. In germ‐free mice, WMT outperforms conventional fecal microbiota transplantation (FMT) in restoring gut microbiota diversity and abundance.
Bufu Tang, Yuan Cao, Jiasu Li, Nan Gao, Pingting Gao, Xiaochao Chen, Zunzhen Ming, Zhaoshen Li, Weiliang Hou   +8 more
wiley   +1 more source

Extracellular Vesicles in Nonalcoholic Fatty Liver Disease: Mechanisms and Therapeutic Opportunities

iNew Medicine, Volume 1, Issue 1, December 2025.
The role of extracellular vesicles (EVs) in the progression of nonalcoholic fatty liver disease (NAFLD). Donor cells release EVs containing various molecules such as cholesterol, ceramide, sphingomyelin, miRNA, DNA, proteins, and lipids. These EVs are taken up by multiple recipient cells including Kupffer cells, adipocytes, β cells, adipose tissue ...
Yunsheng Dong, Lei Xiong, Nina Zhu, Zihan Wang, Hanqi Xia, Chen Cheng, Jianshang Huang, Yiran Han, Abduxukur Rahman, Junhao Zhao, Chonggui Jiang, Li Zuo, Hua Wang   +12 more
wiley   +1 more source

Clostridioides difficile Infection

Clinics in Colon and Rectal Surgery, 2020
Linda, Ferrari, Alessandro, Fichera
openaire   +5 more sources

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

Frontiers in Cellular and Infection Microbiology
Clostridioides difficile infection (CDI) is a significant cause of antibiotic-associated diarrhea and pseudomembranous colitis, manifesting as mild diarrhea, fulminant colitis, and even death.
Xin Wen, Xue Liu, Kai Wan, Hong Liu, Cheng Zhang, Xi Zhang, Qin Wen   +6 more
doaj   +1 more source

Clostridioides difficile Enteritis Induced Anastomotic Rupture: A Case Report and Literature Review

Case Reports in Surgery, 2020
Background. A 76-year-old male patient who suffered small bowel anastomotic dehiscence believed to be a complication provoked by Clostridioides difficile enteritis. Case Presentation. The patient was a 76-year-old male who underwent small bowel resection
David R. Velez, Mentor Ahmeti
doaj   +1 more source

Next‐Generation Sequencing in Infectious‐Disease Diagnostics: Economic, Regulatory, and Clinical Pathways to Adoption

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Next‐generation sequencing (NGS) is poised to transform infectious‐disease diagnostics. Falling per‐sample costs, new CPT codes and FDA pathways, and 24‐h, multiplexed resistome reports converge to deliver faster, evidence‐based therapy and stronger surveillance. Our roadmap links the economic, regulatory, and clinical pillars to accelerate routine NGS
John Osei Sekyere
wiley   +1 more source

A Computational Framework to Quantify Host-Microbiome Interactions in Clostridioides Difficile Infection [PDF]

, 2020
Shanlin Ke, Nira R. Pollock, Wang Xu-wen, Xinhua Chen, Kaitlyn Daugherty, Qianyun Lin, Hua Xu, Kevin W. Garey, Anne J Gonzales-Luna, Yang‐Yu Liu, Ciarán P. Kelly   +10 more
openalex   +1 more source

Rapid-format recombinant antibody-based methods for the diagnosis of Clostridioides difficile infection: Recent advances and perspectives [PDF]

, 2022
Hamideh Raeisi, Masoumeh Azimirad, Hamid Asadzadeh Aghdaei, Abbas Yadegar, Mohammad Reza Zali   +4 more
openalex   +1 more source

The Role of Machine Learning in Addressing Antibiotic Resistance: A New Era in Infectious Disease Control

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Artificial intelligence accelerates the discovery of new antibiotics by rapidly analyzing vast chemical libraries to combat antimicrobial resistance effectively. AI systems predict antibiotic resistance trends, helping researchers design targeted therapies, and prevent the spread of multidrug‐resistant infections. ABSTRACT Antimicrobial resistance (AMR)
Akmal Zubair, Mohd Fazil, Muhammad Jawad, Safa Wdidi   +3 more
wiley   +1 more source

SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial [PDF]

, 2020
Barbara McGovern, Christopher B. Ford, Matthew R. Henn, Darrell S. Pardi, Sahil Khanna, Elizabeth Hohmann, Edward J. O’Brien, Christopher A. Desjardins, Patricia Bernardo, Jennifer R. Wortman, Mary-Jane Lombardo, Kevin Litcofsky, Jonathan Winkler, Christopher McChalicher, Sunny S. Li, Amelia D. Tomlinson, Madhumitha Nandakumar, David N. Cook, Roger J. Pomerantz, John Auniņš, Michele Trucksis   +20 more
openalex   +1 more source