Results 71 to 80 of about 18,494 (211)

Case report of two patients with recurrent watery stools following prophylactic ileostomy reversal after rectal cancer surgery

结直肠肛门外科
The causes of diarrhea after enterostomy reversal may be related to surgical treatment, and its severity varies. Clinical interventions are often based on the patient’s symptomatic presentation.
Shen Shuai, Gao Hui
doaj   +1 more source

The Effect of Climate Change on Emergence and Evolution of Zoonotic Diseases in Asia

Zoonoses and Public Health, Volume 72, Issue 7, Page 587-611, November 2025.
ABSTRACT As the climate of Asia changes under the influence of global warming, the incidence and spatial distribution of known zoonoses will evolve, and new zoonoses are expected to emerge as a result of greater exposure to organisms which currently occur only in wildlife.
Roger S. Morris, Masako Wada
wiley   +1 more source

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Ionizing radiation disrupts gut virome and bacteriome. Gut commensal viruses protect against intestinal damage and promote stem cell regeneration by inhibiting hyperactivation of RIG‐I and Notch signaling in stem cells. Fecal virome transplantation (FVT) from healthy donors can serve as a potential therapeutic intervention by enriching phages targeting
Xiaotong Zhao, Yu Cai, Yujia Hou, Yanjin Wu, Tingting Wei, Lili Li, Zhaojun Duan, Xinran Lu, Jiahui Meng, Haitao Zhou, Qin Wang, Jinhan Wang, Chang Xu, Liqing Du, Saijun Fan, Feng Wang, Qiang Liu, Yang Liu   +17 more
wiley   +1 more source

Half‐Pipe Melt Electrowritten Scaffolds Support Engineering of an Immunocompetent Hydrogel‐Embedded Intestine‐on‐a‐Chip

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The immunocompetent Intestine‐on‐a‐Chip (IoC) is developed using melt electrowritten (MEW) half‐pipes. Intestinal epithelial cell (IEC) culture is optimized in the MEW‐based IoC, followed by co‐culture with monocyte‐derived dendritic cells (moDCs) and T cells in 3D hydrogels.
Robine Janssen, Henrike S. Schulze, Claire M. L. Nelissen, Marta G. Valverde, Andrei Hrynevich, Govardus A. H. de Jong, Anne Metje van Genderen, Jos Malda, Shanna Bastiaan‐Net, Linette E. M. Willemsen, Rosalinde Masereeuw   +10 more
wiley   +1 more source

Targeting gut microbiota and metabolites in cancer radiotherapy

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Radiotherapy (RT) efficacy and toxicity are influenced by gut microbiota and their metabolites. This review explores how probiotics, prebiotics, and microbial byproducts (e.g., short‐chain fatty acids [SCFAs]) mitigate radiation damage and enhance tumour radiosensitivity.
Shuling Ma, Xinpei Li, Shijie Shang, Zijun Zhai, Meng Wu, Qian Song, Dawei Chen   +6 more
wiley   +1 more source

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

Frontiers in Cellular and Infection Microbiology
Clostridioides difficile infection (CDI) is a significant cause of antibiotic-associated diarrhea and pseudomembranous colitis, manifesting as mild diarrhea, fulminant colitis, and even death.
Xin Wen, Xue Liu, Kai Wan, Hong Liu, Cheng Zhang, Xi Zhang, Qin Wen   +6 more
doaj   +1 more source

Clostridioides difficile Enteritis Induced Anastomotic Rupture: A Case Report and Literature Review

Case Reports in Surgery, 2020
Background. A 76-year-old male patient who suffered small bowel anastomotic dehiscence believed to be a complication provoked by Clostridioides difficile enteritis. Case Presentation. The patient was a 76-year-old male who underwent small bowel resection
David R. Velez, Mentor Ahmeti
doaj   +1 more source

Phenotypic and Genetic Characterization and Production Abilities of Lacticaseibacillus rhamnosus Strain 484—A New Probiotic Strain Isolated From Human Breast Milk

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
Human breast milk (HBM) is a recognized source of probiotic bacteria, with species such as Lacticaseibacillus rhamnosus demonstrating considerable potential for applications in both the medical and food industries. In this study, the probiotic potential of strain 484, isolated from HBM, was evaluated through comprehensive phenotypic and genetic ...
Natalia Czarnecka, Magdalena Jankowska, Sylwia Nawrot, Katarzyna Nogal‐Nowak, Sławomir Wąsik, Grzegorz Czerwonka   +5 more
wiley   +1 more source

Viewpoint: The Use of Antimycobacterial (Anti‐MAP) Therapies in the Treatment of Active Luminal Crohn's Disease

JGH Open, Volume 9, Issue 10, October 2025.
ABSTRACT Mycobacterium avium subspecies paratuberculosis (MAP) as the infectious cause of Crohn's disease and the use of antimycobacterial (anti‐MAP) therapies in its treatment remain topics of controversy. A major limitation accepting this view is that irrefutable evidence that MAP causes Crohn's disease—the demonstration that long‐term remission ...
Paul Pavli, Peter R. Gibson
wiley   +1 more source

Freezing of Vaginal Swabs Prior to DNA Purification Does Not Statistically Significantly Affect Microbiome Composition

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
The vaginal microbiome is vital to women's health. We assessed the effects of short‐term storage and human DNA depletion on microbial profiles. While overall composition remained stable, trends in beta diversity and internal controls suggest subtle effects on low‐abundance species, highlighting the need for robust analytical design.
Khaled Saoud Ali Ghathian, Julie Elm Heintz, Sarah Mollerup, Sarah Juel Paulsen, Karen Angeliki Krogfelt, Niels Frimodt‐Møller, Katrine Hartung Hansen, Sofie Ingdam Halkjær, Anne Holm, Mette Pinholt, Andreas Munk Petersen   +10 more
wiley   +1 more source