Results 51 to 60 of about 275 (135)

Pathway for H2O2 and O2 detoxification in Clostridium acetobutylicum [PDF]

Microbiology, 2009
An unusual non-haem diiron protein, reverse rubrerythrin (revRbr), is known to be massively upregulated in response to oxidative stress in the strictly anaerobic bacterium Clostridium acetobutylicum. In the present study both in vivo and in vitro results demonstrate an H2O2 and O2 detoxification pathway in C. acetobutylicum involving revRbr, rubredoxin
Oliver, Riebe, Ralf-Jörg, Fischer, David A, Wampler, Donald M, Kurtz, Hubert, Bahl   +4 more
openaire   +2 more sources

Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica

Advanced Science, Volume 12, Issue 44, November 27, 2025.
The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon, Eun‐Jung Kim, Hogyun Seo, Hyunjin Kim, Seungjin Shin, Caroline Schlaiß, Largus T. Angenent, Kyung‐Jin Kim, Byoung‐In Sang   +8 more
wiley   +1 more source

Cap0037, a Novel Global Regulator of Clostridium acetobutylicum Metabolism

mBio, 2016
An operon comprising two genes, CA_P0037 and CA_P0036, that encode proteins of unknown function that were previously shown to be highly expressed in acidogenic cells and repressed in solventogenic and alcohologenic cells is located on the pSOL1 ...
Ngoc-Phuong-Thao Nguyen, Sonja Linder, Stefanie K. Flitsch, Bettina Schiel-Bengelsdorf, Peter Dürre, Philippe Soucaille   +5 more
doaj   +1 more source

Gut Microbiota‐Bile Acid Metabolism Axis Drive Anti‐Diabetic Effects of Polygonatum cyrtonema Polysaccharide on Glycolipid Metabolism and Intestinal Inflammation

Food Frontiers, Volume 6, Issue 6, Page 2942-2960, November 2025.
PCP‐80% could lessen the pathophysiology of T2DM in terms of controlling blood glucose/lipid levels and enhancing intestinal barrier function, via modulating the intricate web of intestinal microbiota/BAs/BAs signaling pathways. Red vertical arrows denote increases (HPCP‐80% vs. MC), blue vertical arrows indicate decreases (HPCP‐80% vs.
Xiaole Zhao, Bing Zheng, Tianxiang Ao, Jianhua Xie, Yi Chen, Hesham El‐Seedi, Hairong Huang, Baoting Liu, Qiang Yu   +8 more
wiley   +1 more source

A Quantitative System-Scale Characterization of the Metabolism of Clostridium acetobutylicum

mBio, 2015
Engineering industrial microorganisms for ambitious applications, for example, the production of second-generation biofuels such as butanol, is impeded by a lack of knowledge of primary metabolism and its regulation.
Minyeong Yoo, Gwenaelle Bestel-Corre, Christian Croux, Antoine Riviere, Isabelle Meynial-Salles, Philippe Soucaille   +5 more
doaj   +1 more source

Bioactive Compounds Derived From Natural Foods Against Metabolic Syndrome and the Advances of Resveratrol and Caffeic Acid in Microbial Cell Factory Production: A Review

Food Frontiers, Volume 6, Issue 6, Page 2575-2590, November 2025.
Metabolic syndrome is characterized by abdominal obesity, hyperglycemia, dyslipidemia, and hypertension. Bioactive compounds extracted from herbs, tea, and coffee using microbial cell factories, particularly resveratrol and caffeic acid, have demonstrated remarkable potential in the management of metabolic syndrome, offering innovative solutions for ...
Tao Li, Jingjing Shi, Tao Liu, Chongxiang Xue, Lin Han, Mingzhe Zhang, Linhua Zhao, Xiaolin Tong   +7 more
wiley   +1 more source

Effects of Temperature, pH, and Agitation on Growth and Butanol Production of Clostridium acetobutylicum, Clostridium beijerinckii, and Clostridium saccharoperbutylacetonicum

Environmental and Climate Technologies
Butanol is a promising alternative to fossil-derived fuels. Clostridium genus bacteria are known for their ability to produce butanol as one of the metabolites, however, at the moment this solution is not economically viable.
Feldmane Linda, Raita Svetlana, Berzina Indra, Geiba Zane, Mika Taras, Kuzmika Iveta, Spalvins Kriss   +6 more
doaj   +1 more source

Microbial Conversion of Glycerol Into 1,3‐Propanediol by Fermentation: Review of Fundamentals and Operational Strategies

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
This review highlights recent advances in microbial fermentation strategies for converting glycerol, a biodiesel by‐product, into 1,3‐propanediol. It discusses metabolic pathways, microbial inocula and key operational parameters to optimise production, supporting sustainable chemical synthesis aligned with circular economy principles. ABSTRACT Over the
María Fernanda Pérez‐Bernal, Roman Moscoviz, Xiaoli Wang, Nicolas Bernet, Eric Trably   +4 more
wiley   +1 more source

Cross-talk between engineered Clostridium acetobutylicum and Clostridium ljungdahlii in syntrophic cocultures enhances isopropanol and butanol production

Frontiers in Microbiology
There is a need for efficient and sustainable production of essential chemicals such as isopropanol and butanol from renewable sugar feedstocks. Microbial fermentations use glycolysis, and as result, a third of the sugar carbon is lost to CO2 through ...
Jonathan K. Otten, Jonathan K. Otten, John D. Hill, John D. Hill, Noah B. Willis, Noah B. Willis, Joseph Dougherty, Andrew Dalton, Eleftherios T. Papoutsakis, Eleftherios T. Papoutsakis, Eleftherios T. Papoutsakis   +10 more
doaj   +1 more source

CINÉTICA DE LA PRODUCCIÓN DE ACETONA-BUTANOL.

Ingeniería, 2011
Se estudió el cumplimiento cinético de la fermentación acetobutílica, utilizando el clostridium acetobutylicum NRRL-B594. Se empleó almidón de banano al 2% como sustrato, condiciones de pH inicial de 5,5 y temperatura constante de 36ºC.
Manuel Enrique Molina Córdoba, J.R Hernández, U.F. Jiménez   +2 more
doaj   +1 more source