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Infectious Diseases and Therapy, 2023 Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich +15 more
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Clostridium-difficile-Kolitis [PDF]
Der Gastroenterologe, 2014 Die (rezidivierende) Clostridium-difficile-Infektion (CDI) stellt bereits jetzt ein substanzielles Problem dar, sind mit ihr doch nicht nur eine beachtenswerte Morbiditat und Mortalitat assoziiert, sondern auch gesundheitsokonomische und logistische Herausforderungen.
Biedermann, L, Rogler, G
openaire +2 more sources
Clostridium difficile infection [PDF]
The Lancet, 2008 Clostridium difficile is a Gram-positive, anaerobic, spore-producing anaerobe [1] responsible for approximately 50–70% of gastrointestinal infections in hospitalized patients [2, 3]. An episode of C. difficile infection (CDI) is defined as a clinical picture compatible with CDI (i.
Christina M. Surawicz, Ernst J. Kuipers
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Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains [PDF]
, 2013 UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU.
Chang, Barbara J +5 more
core +2 more sources
SplitStrains, a tool to identify and separate mixed Mycobacterium tuberculosis infections from WGS data [PDF]
Microbial Genomics, 7, 2021, 6, 2022 The occurrence of multiple strains of a bacterial pathogen such as M. tuberculosis or C. difficile within a single human host, referred to as a mixed infection, has important implications for both healthcare and public health. However, methods for detecting it, and especially determining the proportion and identities of the underlying strains, from WGS
arxiv +1 more source
New Microbes and New Infections, 2015 Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. difficile are the toxins A (TcdA) and B (TcdB). A third toxin, called binary toxin (CDT), can be detected in 17% to 23% of strains,
C. Eckert +15 more
doaj +1 more source
A Clostridium difficile onkológiai vonatkozásai [PDF]
, 2016 Absztrakt A Clostridium difficile az egyik leggyakoribb fertőzés a daganatos betegek között. Diagnózisát nehezíti, hogy a fertőzés tünetei és az onkológiai kezelések mellékhatásai hasonlóak ...
Telekes, András
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Systematic literature review: Perbandingan Efek Penggunan Jangka Panjang Omeprazole dan Lansoprazole terhadap Peningkatan Infeksi Clostridium difficile [PDF]
, 2021 Pendahuluan: Proton Pump Inhibitor (PPI) merupakan golongan obat yang memiliki efek penghambat pada enzim H+/K+ ATPase secara selektif dalam sel parietal.
Airlangga, Hardadi +2 more
core +1 more source
The pathogenicity of Clostridium difficile [PDF]
Clinical Microbiology and Infection, 2001 It is now well established that the major virulence factors of C. difficile are the two toxins A and B. However, the organism possesses an array of other putative virulence factors that may be important for localisation within the colon, and in evasion of the immune system. It has been observed that certain types of C. difficile are more commonly found
Ian R. Poxton, J. McCoubrey, G. Blair
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Clostridium difficile Infection [PDF]
Medical Clinics of North America, 2013 Clostridium difficile is emerging as a common cause of infectious diarrhea. Incidence has increased dramatically since 2000, associated with a new strain that features both increased toxin production and increased resistance to antibiotics. For patients with mild to moderate disease, oral metronidazole is usually the first choice of treatment, and ...
Christina M. Surawicz +1 more
+10 more sources