Diarrhea associated with Clostridium difficile in the oncology clinic
Purpose of the study. To conduct typing of toxigenic strains of Clostridium difficile, obtained from oncological patients who are in hospital.Material and Methods. The study included 130 patients with Clostridium difficile – associated diarrhea.
I. A. Klyuchnikova +6 more
doaj +1 more source
Characterization of the Adherence of Clostridium difficile Spores: The Integrity of the Outermost Layer Affects Adherence Properties of Spores of the Epidemic Strain R20291 to Components of the Intestinal Mucosa [PDF]
Indexación: Web of Science.Clostridium difficile is the causative agent of the most frequently reported nosocomial diarrhea worldwide. The high incidence of recurrent infection is the main clinical challenge of C. difficile infections (CBI). Formation of
Banawas, Saeed +9 more
core +2 more sources
Risk factors for infection in HIV-infected patients
Background: Clostridium difficile infection is a healthcare-associated infection resulting in significant morbidity. Although immunosuppression is associated with Clostridium difficile infection acquisition and adverse outcomes, the epidemiology of ...
Hannah Imlay, Daniel Kaul, Krishna Rao
doaj +1 more source
Polyclonal Antibody Therapies for Clostridium difficile Infection
Clostridium difficile infection has emerged as a growing worldwide health problem. The colitis of Clostridium difficile infection results from the synergistic action of C. difficile secreted toxins A and B upon the colon mucosa.
Michael R. Simon +2 more
doaj +1 more source
Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria [PDF]
Clostridium difficile is a Gram-positive spore-forming anaerobe and a major cause of antibiotic-associated diarrhoea. Disruption of the commensal microbiota, such as through treatment with broad-spectrum antibiotics, is a critical precursor for ...
Baines, Simon D +12 more
core +6 more sources
Clostridium difficile – still a problem among the XXI century in case of geriatic patient
Introduction. The disease caused by Clostridium difficile (CzcD - Clostridium difficile -associated disease) - was defined by the Centres for Disease Control and Prevention in Atlanta in 2007 in order to standardize monitoring conditions of diarrhea ...
Agnieszka Ulatowska +7 more
doaj +1 more source
Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L. +13 more
core +1 more source
A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection [PDF]
Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia.
Beamer, Gillian +12 more
core +2 more sources
Faecal microbiota transplantation : a regulatory hurdle? [PDF]
During faecal microbiota transplantation, stool from a healthy donor is transplanted to treat a variety of dysbiosis-associated gut diseases. Competent authorities are faced with the challenge to provide adequate regulation.
De Spiegeleer, Bart +3 more
core +2 more sources
Molecular epidemiology of endemic Clostridium difficile infection [PDF]
This is the first study to provide a comprehensive insight into the molecular epidemiology of endemic Clostridium difficile and particularly that associated with a recently recognized epidemic strain. We DNA fingerprinted all C.
Fawley, W.N., Wilcox, M.H.
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