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Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria [PDF]
, 2018 Clostridium difficile is a Gram-positive spore-forming anaerobe and a major cause of antibiotic-associated diarrhoea. Disruption of the commensal microbiota, such as through treatment with broad-spectrum antibiotics, is a critical precursor for ...
Baines, Simon D +12 more
core +6 more sources
Aerial dissemination of Clostridium difficile spores [PDF]
, 2008 Background: Clostridium difficile-associated diarrhoea (CDAD) is a frequently occurring healthcare-associated infection, which is responsible for significant morbidity and mortality amongst elderly patients in healthcare facilities.
A Rahmati +36 more
core +3 more sources
In vitro activities of MCB3681 and 8 comparators against Clostridium difficile isolates with known ribotypes and diverse geographical spread [PDF]
, 2017 Treatments for Clostridium difficile infection remain limited, despite the introduction of fidaxomicin, and development of new agents is necessary.
Freeman, J +3 more
core +1 more source
Typing of Clostridium difficile [PDF]
Clinical Microbiology and Infection, 2001 Clostridium difficile is primarily recognised as a nosocomially acquired pathogen manifesting in gastrointestinal disease subsequent to the patient receiving broad-spectrum antibiotics. Infection can be sporadic, but outbreaks commonly occur within a ward or hospital as a result of cross-infection. Since the 1980s, the epidemiology of C.
openaire +3 more sources
International Journal of Infectious Diseases, 2020 Background: Clostridioides difficile is the major cause of infectious nosocomial diarrhoea in industrialized nations. Data on the occurrence of C. difficile in Africa, ribotype (RT) distribution, antimicrobial susceptibility patterns and potential ...
Fabian K. Berger +6 more
doaj
Clostridium difficile infection
Autopsy and Case Reports, 2014 Clostridium difficile infection (CDI) is a significant and increasing medical problem, surpassing methicillin-resistant Staphylococcus aureus as the most common hospital-onset or facility-associated infection, and a key element in the challenging battle against hospital-acquired infections.
Fernando Peixoto Ferraz de Campos +1 more
openaire +4 more sources
Balkan Medical Journal, 2018 Aims: To investigate the epidemiology of Clostridium difficile infection in Romanian hospitals. Methods: A survey was conducted at nine hospitals throughout Romania between November 2013 and February 2014.
Gabriel Adrian Popescu +8 more
doaj +1 more source
A rare case of clostridium difficile infection-associated reactive arthritis [PDF]
, 2018 Clostridium difficile is an uncommon cause of reactive arthritis in children. We herein present a rare case of C. difficile infection-associated reactive arthritis (CDIAReA) in a child, who developed severe diarrhea and a knee effusion following a course
Derinkuyu, B.E. +3 more
core +1 more source
Disarming Clostridium difficile
Chemistry & Biology, 2010 In this issue, Puriet al. (2010) present inhibitors that prevent the autocatalytic activation of the clostridial toxin TcdB in vivo. Their approach is likely to provide guidance for the development of novel drugs targeting virulence factors and thereby rendering bacterial pathogens innocuous.
Malte Gersch, Stephan A. Sieber
openaire +3 more sources
Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated Infection
Журнал инфектологии, 2014 In the review the current information on the laboratory diagnosis of Clostridium difficile-associated infection. Made a critical assessment of the effectiveness and specificity of the modern methods of diagnosis: methods of isolation and identification ...
A. S. Kvet naya, +2 more
doaj +1 more source