Results 61 to 70 of about 55,569 (166)

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

A review on the effects of probiotics and antibiotics towards Clostridium difficile infections [PDF]

, 2013
Clostridium difficile can cause severe diseases with significant morbidity and mortality in infected patients. The rate of Clostridium difficile infection is high in North America and European countries. Metronidazole and vancomycin have been recommended
Abd Manap, Mohd Yazid, Abdul Aziz, Rushdan, Awang Hamat, Rukman, Azman, Hazirah, Loong, Yik Yee   +4 more
core  

A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways. [PDF]

, 2020
Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization.
Bier, Ethan, Franc, Nathalie C, Guichard, Annabel, Roy, Sitara, Schwartz, Ruth   +4 more
core  

Infection Clostridium difficile as increasing epidemiological issue

Journal of Education, Health and Sport, 2017
Introduction: Clostridium difficile as an infectious agent of pseudomembranous enterocolitis, becomes more and more frequent problem among health facilities.
Maciej Rutkowski, Anna Roszkowska, Lukasz Swierszcz, Halina Piecewicz-Szczęsna   +3 more
doaj   +3 more sources

Contribution of Inhibitory Metabolites and Competition for Nutrients to Colonization Resistance against Clostridioides difficile by Commensal Clostridium

Microorganisms, 2021
Clostridioides difficile is an anaerobic pathogen that causes significant morbidity and mortality. Understanding the mechanisms of colonization resistance against C. difficile is important for elucidating the mechanisms by which C.
Amber D. Reed, Casey M. Theriot
doaj   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Detection of Clostridium difficile associated diarrhea in disease based on Polymerase chain reaction and bacterial culture And toxin A, B frequency [PDF]

Journal of Advanced Biomedical Sciences, 2019
Detection of Clostridium Difficile Associated Diarrhea in Disease Based on Polymerase Chain Reaction and Bacterial Culture and Toxin A, B Frequency Detection of Clostridium Difficile Associated Diarrhea in Disease Background & Objective: Clostridium ...
mohsen zargar, ali javadi, abbas morovvati   +2 more
doaj  

A search for Clostridium difficile ribotypes 027 and 078 in Brazil

Brazilian Journal of Infectious Diseases, 2014
Toxigenic strains of Clostridium difficile may be disseminating. Here we prospectively screened patients with nosocomial diarrhoea in two hospitals in Brazil. To identify C.
Alexandre de Almeida Monteiro, Renata Neto Pires, Søren Persson, Edison Moraes Rodrigues Filho, Alessandro Comarú Pasqualotto   +4 more
doaj   +1 more source

Oral proton‐reprogrammed nanomedicine to break the inflammatory bowel disease‐Clostridium difficile infection vicious cycle

iMeta, EarlyView.
Research on the mechanism of OPR restoring intestinal epithelial cell (IEC) structure and function in inflammatory bowel disease (IBD) treatment. (A) Schematic diagram of OPR structure and the rate of GP release under different conditions. (B) Schematic diagram of OPR targeting IBD colonic lesions through charge interaction.
Wensheng Chen, Yuntao Zhang, Jue Wang, Yiming Li, Hao Wu, Qiong Huang, Wei Wu, Kelong Ai   +7 more
wiley   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source