Results 61 to 70 of about 113,640 (277)

Characterization of the Adherence of Clostridium difficile Spores: The Integrity of the Outermost Layer Affects Adherence Properties of Spores of the Epidemic Strain R20291 to Components of the Intestinal Mucosa [PDF]

, 2016
Indexación: Web of Science.Clostridium difficile is the causative agent of the most frequently reported nosocomial diarrhea worldwide. The high incidence of recurrent infection is the main clinical challenge of C. difficile infections (CBI). Formation of
Banawas, Saeed, Calderón, Iván, Castro-Córdova, Pablo, Fuentes, Juan A., Gil, Fernando, Miranda-Cárdenas, Camila, Mora-Uribe, Paola, Paredes-Sabja, Daniel, Rodas, Paula I., Sarker, Mahfuzur R.   +9 more
core   +2 more sources

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Prevalence of Actionable Pharmacogenetic Genotype Frequencies, Cautionary Medication Use, and Polypharmacy in Community‐Dwelling Older Adults

Clinical Pharmacology &Therapeutics, EarlyView.
Older adults (65 years and over) frequently manage complex medication regimens and are vulnerable to adverse drug reactions and treatment inefficacies, some of which could be preventable with pharmacogenetics (PGx)‐guided prescribing. This study examined the prevalence of actionable PGx genotypes (i.e., those linked to a guideline that recommends a ...
Chad A. Bousman, Ankita Narang, Ziad Al Bkhetan, Robyn L. Woods, Suzanne G. Orchard, Alice J. Owen, Michelle A. Fravel, Julia Gilmartin‐Thomas, Joanne Ryan, Peter D. Fransquet, Rory Wolfe, Chenglong Yu, John J. McNeil, Paul Lacaze, Michael E. Ernst   +14 more
wiley   +1 more source

Infection Clostridium difficile as increasing epidemiological issue

Journal of Education, Health and Sport, 2017
Introduction: Clostridium difficile as an infectious agent of pseudomembranous enterocolitis, becomes more and more frequent problem among health facilities.
Maciej Rutkowski, Anna Roszkowska, Lukasz Swierszcz, Halina Piecewicz-Szczęsna   +3 more
doaj   +3 more sources

Role of Microbiota and Innate Immunity in Recurrent Clostridium difficile Infection

Journal of Immunology Research, 2014
Recurrent Clostridium difficile infection represents a burdensome clinical issue whose epidemiology is increasing worldwide. The pathogenesis is not yet completely known.
Stefano Bibbò, Loris Riccardo Lopetuso, Gianluca Ianiro, Teresa Di Rienzo, Antonio Gasbarrini, Giovanni Cammarota   +5 more
doaj   +1 more source

An atypical case of infection by Clostridium difficile

Microbiologia Medica, 2010
Clostridium difficile is a Gram-positive human pathogenic bacterium and nosocomial pathogen; it is the causative agent diarrhoea, colitis and pseudo-membranous colitis associated with antibiotic therapy.
Maria Cristina Neri, Nadia Antoniotti, Maria Benvenuto, Sergio Frugoni, Francesco Riboldi, Vito Noto   +5 more
doaj   +1 more source

A review on the effects of probiotics and antibiotics towards Clostridium difficile infections [PDF]

, 2013
Clostridium difficile can cause severe diseases with significant morbidity and mortality in infected patients. The rate of Clostridium difficile infection is high in North America and European countries. Metronidazole and vancomycin have been recommended
Abd Manap, Mohd Yazid, Abdul Aziz, Rushdan, Awang Hamat, Rukman, Azman, Hazirah, Loong, Yik Yee   +4 more
core  

Faecal microbiota transplantation : a regulatory hurdle? [PDF]

, 2017
During faecal microbiota transplantation, stool from a healthy donor is transplanted to treat a variety of dysbiosis-associated gut diseases. Competent authorities are faced with the challenge to provide adequate regulation.
De Spiegeleer, Bart, Janssens, Yorick, Verbeke, Frederick, Wynendaele, Evelien   +3 more
core   +2 more sources

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

Barrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

Contribution of Inhibitory Metabolites and Competition for Nutrients to Colonization Resistance against Clostridioides difficile by Commensal Clostridium

Microorganisms, 2021
Clostridioides difficile is an anaerobic pathogen that causes significant morbidity and mortality. Understanding the mechanisms of colonization resistance against C. difficile is important for elucidating the mechanisms by which C.
Amber D. Reed, Casey M. Theriot
doaj   +1 more source