Results 61 to 70 of about 277,449 (338)

Editorial for the Special Issue: Clostridium difficile

open access: yesMicroorganisms, 2021
Clostridium difficile (reclassified as Clostridioides difficile [...]
Łukasz M. Grześkowiak
doaj   +1 more source

A microbiota-generated bile salt induces biofilm formation in Clostridium difficile

open access: yesnpj Biofilms and Microbiomes, 2019
Clostridium difficile is a major cause of nosocomial infections. Bacterial persistence in the gut is responsible for infection relapse; sporulation and other unidentified mechanisms contribute to this process.
T. Dubois   +7 more
semanticscholar   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

open access: yesAdvanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor   +12 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Clostridium difficile infection outbreak in a male rehabilitation ward, Hong Kong (China), 2011

open access: yesWestern Pacific Surveillance and Response, 2012
Clostridium difficile is an anaerobic, gram-positive bacterium, capable of sporulation when environmental conditions no longer support its growth. The sporulation capacity enables the organism to persist in the environment for extended periods of time ...
Man-ha Wong   +4 more
doaj   +1 more source

A Two‐Stage Cascading Amplification Strategy Based on Zn2+‐Doped WOX Nanozymes for Ultrasensitive Lateral Flow Immunoassays of Clostridium Difficile Toxin B

open access: yesAdvanced Science, EarlyView.
Based on the modulation of active sites and electronic structure of substrate materials, along with a colorimetric two‐stage cascading enhancement strategy, an LFIA platform with highly efficient POD‐mimetic enzymes is developed, achieving highly sensitive detection of Clostridium difficile toxin B.
Junhua Su   +6 more
wiley   +1 more source

A review on the effects of probiotics and antibiotics towards Clostridium difficile infections [PDF]

open access: yes, 2013
Clostridium difficile can cause severe diseases with significant morbidity and mortality in infected patients. The rate of Clostridium difficile infection is high in North America and European countries. Metronidazole and vancomycin have been recommended
Abd Manap, Mohd Yazid   +4 more
core  

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

open access: yesAdvanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou   +16 more
wiley   +1 more source

An atypical case of infection by Clostridium difficile

open access: yesMicrobiologia Medica, 2010
Clostridium difficile is a Gram-positive human pathogenic bacterium and nosocomial pathogen; it is the causative agent diarrhoea, colitis and pseudo-membranous colitis associated with antibiotic therapy.
Maria Cristina Neri   +5 more
doaj   +1 more source

Contribution of Inhibitory Metabolites and Competition for Nutrients to Colonization Resistance against Clostridioides difficile by Commensal Clostridium

open access: yesMicroorganisms, 2021
Clostridioides difficile is an anaerobic pathogen that causes significant morbidity and mortality. Understanding the mechanisms of colonization resistance against C. difficile is important for elucidating the mechanisms by which C.
Amber D. Reed, Casey M. Theriot
doaj   +1 more source

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