Results 141 to 150 of about 113,759 (264)

Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With VEXAS Syndrome: An International Multicenter Study

Arthritis &Rheumatology, Volume 78, Issue 2, Page 475-482, February 2026.
Objective The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome. Methods This multicenter international study includes patients with VEXAS from France, Israel, and Italy treated with ...
Tali Eviatar, Dafne Capelusnik, Corrado Campochiaro, Valentin Lacombe, Vincent Jachiet, Michael Zisapel, Iftach Sagy, Oshrat E. Tayer‐Shifman, David Ozeri, Shaye Kivity, Alessandro Tomelleri, Benjamin Terrier, Hagit Peleg, Thibault Comont, Karim Sacre, Pascal Woaye‐Hune, Laurent Arnaud, Estibaliz Lazaro, Vincent Grobost, Francois Lifermann, Maxime Samson, Samuel Ardois, Alice Garnier, Alexandre Maria, Alain Cantagrel, Aurore Meyer, Jean‐David Bouaziz, Mael Heiblig, Lorenzo Dagna, Elisa Diral, Olivier Kosmider, Ori Elkayam, Jérôme Hadjadj, Sophie Georgin‐Lavialle, Olivier Fain, Arsene Mekinian   +35 more
wiley   +1 more source

FECAL CALPROTECTIN AS A MARKER OF INFLAMMATION IN THE COLON AT DIFFERENT VARIANTS OF CLOSTRIDIUM DIFFICILE-INFECTIONS COURSE IN CHILDREN

Детские инфекции (Москва), 2015
The article discusses possible application of determination of the fecal calprotectin level in children with antibiotic-associated diarrhea caused by Clostridium difficile — infection to detect inflammation in various parts of the gastrointestinal tract.
L. N. Mazankova, S. G. Gorbunov, B. Yunes   +2 more
doaj   +1 more source

Modulating the Gut Microbiome as a Therapeutic Approach in Multiple Sclerosis: Implications for Gut‐Brain Interactions and Immune Pathways: A Narrative Review

Brain and Behavior, Volume 16, Issue 2, February 2026.
The gut microbiome in multiple sclerosis (MS) shows consistent depletion of short‐chain fatty acid (SCFA)‐producing bacteria, expansion of pro‐inflammatory species, and reduced levels of butyrate, propionate, and indole metabolites. These alterations increase intestinal permeability, disrupt immune balance, and contribute to blood–brain barrier ...
Husna Irfan Thalib, Nuha Fatima, Faaleha Heba Fakruddin, Hosna Hamidullah Ali, Sariya Khan, Mohammed Talha Mohammed Zubair, Mable Pereira, Fatma E. Sayed Hassan   +7 more
wiley   +1 more source

A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation

Gut and Liver, 2015
Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%.
doaj   +1 more source

Key Research Issues in Clostridium difficile

Canadian Journal of Infectious Diseases and Medical Microbiology, 2005
Clostridium difficile is an emerging pathogen that causes C difficile-associated diarrhea, an important nosocomial infection. Control of this infection remains a challenge, and much needs to be determined about the antimicrobial resistance of the ...
George Zhanel, Greg Hammond
doaj   +1 more source

Clinical and Pathological Features of Ulcerative Colitis in Patients with and without Clostridium Difficile Infection; An Observational Study

Middle East Journal of Digestive Diseases, 2019
BACKGROUND A dramatic rise in the rate of clostridium difficile infection (CDI) in patients with inflammatory bowel disease (IBD) has been reported in recent years. METHODS In this observational case control study, 65 patients ulcerative colitis (UC)
Najmeh Aletaha, Zohreh Dadvar, Babak Salehi, Pardis Ketabi Moghadam, Ali Niksirat, Akram Jowkar, Reza Taslimi, Seyed Farshad Allameh, Naser Ebrahimi Daryani   +8 more
doaj   +1 more source

Gut microbiota and central nervous system's direct bidirectional regulation: The mechanisms of the gut–brain axis in irritable bowel syndrome

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Gut microbiota directly modulates central nervous system activity via vagal, sympathetic and sensory neural circuits. Brainstem nuclei integrate microbial signals to regulate gut motility, secretion and visceral sensitivity. DRG neurons and stress‐responsive pathways link microbial cues to host defence and epithelial homeostasis. Dysregulated gut–brain
Jinxia Zhai, Yingjie Li, Jiameng Liu, Cong Dai   +3 more
wiley   +1 more source

Examination of Clostridium difficile Contamination in beef meat distributed in Isfahan using culture and Multiplex-PCR method

Biological Journal of Microorganism, 2014
Introduction: With regard to increasing of community associated Clostridium difficile infection in recent years, the probable transmission of Clostridium difficile from food to human was supposed.
zahra Esfandiari, Mohammad Jalali, Hamid Ezzatpanah, Scott Weese, Mohammad Chamani   +4 more
doaj  

Effects of Age, Sex, and Social Network on Antibiotic Resistance Genes in the Gut Microbiome of Tibetan Macaques (Macaca thibetana)

Ecology and Evolution, Volume 16, Issue 2, February 2026.
Based on metagenomic and behavioral data from wild Tibetan macaques, this study reveals a unique gut resistome profile dominated by multidrug resistance genes. While individual factors like age, sex, and social centrality did not affect overall ARG diversity, they significantly influenced the abundance of specific, high‐prevalence ARGs.
Yue Ling, Dong‐Xin Yang, Ying‐Na Xia, Chuan‐Peng Bao, Fan Zhang, Xiao‐Juan Xu, Bing‐Hua Sun   +6 more
wiley   +1 more source

Detection of Clostridium difficile associated diarrhea in disease based on Polymerase chain reaction and bacterial culture And toxin A, B frequency [PDF]

Journal of Advanced Biomedical Sciences, 2019
Detection of Clostridium Difficile Associated Diarrhea in Disease Based on Polymerase Chain Reaction and Bacterial Culture and Toxin A, B Frequency Detection of Clostridium Difficile Associated Diarrhea in Disease Background & Objective: Clostridium ...
mohsen zargar, ali javadi, abbas morovvati   +2 more
doaj