High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]
Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon +9 more
core +2 more sources
Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L. +13 more
core +1 more source
Clostridium difficile Infection [PDF]
Preventing Clostridium difficile, the most common cause of health care–associated infections in hospitals and infectious disease death in the United States, is a national priority. Increased rates of infection among low-risk individuals in the community call for community-based prevention efforts to halt the increasing spread of this highly contagious
Jennan A, Phillips, Stephanie, Hammond
openaire +2 more sources
Characterization of the Adherence of Clostridium difficile Spores: The Integrity of the Outermost Layer Affects Adherence Properties of Spores of the Epidemic Strain R20291 to Components of the Intestinal Mucosa [PDF]
Indexación: Web of Science.Clostridium difficile is the causative agent of the most frequently reported nosocomial diarrhea worldwide. The high incidence of recurrent infection is the main clinical challenge of C. difficile infections (CBI). Formation of
Banawas, Saeed +9 more
core +2 more sources
A rare case of clostridium difficile infection-associated reactive arthritis [PDF]
Clostridium difficile is an uncommon cause of reactive arthritis in children. We herein present a rare case of C. difficile infection-associated reactive arthritis (CDIAReA) in a child, who developed severe diarrhea and a knee effusion following a course
Derinkuyu, B.E. +3 more
core +1 more source
Background Hospitalization and antibiotic treatment can put patients at high risk for Clostridium difficile infection, where a disturbance of the gut microbiome allows for Clostridium difficile proliferation and associated symptoms, including mild ...
Maureen Hitschfeld +8 more
doaj +1 more source
Faecal microbiota transplantation : a regulatory hurdle? [PDF]
During faecal microbiota transplantation, stool from a healthy donor is transplanted to treat a variety of dysbiosis-associated gut diseases. Competent authorities are faced with the challenge to provide adequate regulation.
De Spiegeleer, Bart +3 more
core +2 more sources
BACKGROUND & AIMS Fecal microbiota transplantation (FMT) is recommended for treatment of recurrent Clostridium difficile infection (rCDI). We performed a single-center randomized trial to compare the effects of FMT with those of fidaxomicin and ...
C. Hvas +7 more
semanticscholar +1 more source
Extraintestinal Clostridium difficile Infections [PDF]
SCOPUS: ar.j ; info:eu-repo/semantics ...
Byl, Baudouin +3 more
openaire +2 more sources
Infections caused by Clostridium difficile in cancer patients
The purpose of the study was to determine the role of antibiotics as a risk factor of Clostridium difficile-associated diarrhea in hospitalized cancer patients.Material and Methods. The study included 844 hospitalized cancer patients with diarrhea.
I. A. Klyuchnikova +5 more
doaj +1 more source

