A re-entrant phase transition in the survival of secondary infections on networks [PDF]
We study the dynamics of secondary infections on networks, in which only the individuals currently carrying a certain primary infection are susceptible to the secondary infection. In the limit of large sparse networks, the model is mapped to a branching process spreading in a random time-sensitive environment, determined by the dynamics of the ...
arxiv +1 more source
Sugar‐sensing swodkoreceptors and swodkocrine signaling
Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley +1 more source
Some simple rules for estimating reproduction numbers in the presence of reservoir exposure or imported cases [PDF]
The basic reproduction number ($R_0$) is a threshold parameter for disease extinction or survival in isolated populations. However no human population is fully isolated from other human or animal populations. We use compartmental models to derive simple rules for the basic reproduction number for populations with local person-to-person transmission and
arxiv
Clostridium difficile colitis in patients after kidney and pancreas-kidney transplantation [PDF]
Limited data exist about Clostridium difficile colitis (CDC) in solid organ transplant patients. Between 1/1/99 and 12/31/02, 600 kidney and 102 pancreas–kidney allograft recipients were transplanted.
Basu, A+8 more
core +1 more source
Complete high-quality genome sequence of Clostridium limosum (Hathewaya limosa) isolate 14S0207, recovered from a cow with suspected blackleg in Germany [PDF]
Clostridium limosum can be found in soil and the intestinal tract of animals. In 2014, C. limosum was isolated from a suspected blackleg outbreak in cattle in Schleswig-Holstein, Germany. We present a complete genome sequence of a C.
Abdel-Glil, Mostafa Y.+7 more
core +1 more source
Fluid fragmentation from hospital toilets [PDF]
Hospital-acquired infections represent significant health and financial burdens to society. Clostridium difficile (C. difficile) is a particularly challenging bacteria with the potential to cause severe diarrhea and death. One mode of transmission for C.
arxiv
Spatially dense stochastic epidemic models with infection-age dependent infectivity [PDF]
We study an individual-based stochastic spatial epidemic model where the number of locations and the number of individuals at each location both grow to infinity. Each individual is associated with a random infection-age dependent infectivity function. Individuals are infected through interactions across the locations with heterogeneous effects.
arxiv
Extraintestinal Clostridium difficile Infections [PDF]
Clostridium difficile causes diarrhea that ranges from a benign, self-limiting antibiotic use-associated disease to a life-threatening pseudomembranous colitis. Clostridium difficile has rarely been isolated in extraintestinal infections. Our objective was to characterize clinical features and risk factors of these infections.
Perttu Arkkila+5 more
openaire +3 more sources
Stiffness of the C-terminal disordered linker affects the geometry of the active site in endoglucanase Cel8A [PDF]
Cellulosomes are complex multi-enzyme machineries which efficiently degrade plant cell-wall polysaccharides. The multiple domains of the cellulosome proteins are often tethered together by intrinsically disordered regions. The properties and functions of these disordered linkers are not well understood. In this work, we study endoglucanase Cel8A, which
arxiv +1 more source
Hospital environment as a reservoir for cross transmission. Cleaning and disinfection procedures [PDF]
Background. Healthcare associated infections (HAIs) represent a serious problem for public health, as they increase the morbidity and mortality rates, present a relevant financial burden, and significantly contribute to the antimicrobial resistance ...
Cammalleri, V.+4 more
core +1 more source