Results 281 to 290 of about 3,472,654 (379)

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang   +12 more
wiley   +1 more source

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao   +13 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Woman With Vomiting and Fever. [PDF]

open access: yesJ Am Coll Emerg Physicians Open
Sun J, Zhao A, Li X, Liu Y.
europepmc   +1 more source

Impact of Low Preoperative Prognostic Immune Nutritional Index on Survival and Postoperative Infectious Complications in Patients With Colorectal Cancer

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 154-166, January 2026.
This study investigated the prognostic value of the preoperative prognostic immune nutritional index (PINI) in colorectal cancer. A low preoperative PINI was significantly associated with both poor oncological outcomes and an increased risk of postoperative infectious complications.
Shinji Yamashita   +9 more
wiley   +1 more source

Blackleg in cattle in Kazakhstan: regional epizootology, seasonal patterns, and molecular identification of the pathogen. [PDF]

open access: yesFront Vet Sci
Mussoyev A   +10 more
europepmc   +1 more source

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