Results 51 to 60 of about 3,472,654 (379)

UK Renal Registry 18th Annual Report : Chapter 12 Epidemiology of Reported Infections amongst Patients Receiving Dialysis for Established Renal Failure in England 2013 to 2014: a Joint Report from Public Health England and the UK Renal Registry [PDF]

, 2016
From 1st May 2013 to 30th April 2014 there were 35 episodes of Methicillin resistant Staphylococcus aureus (MRSA) bacteraemia in established renal failure patients on dialysis.
Caskey, Fergus, Crowley, Lisa, Davies, John, Evans, Rebecca, Farrington, Ken, Fluck, Richard, Nsonwu, Olisaeloka   +6 more
core   +4 more sources

Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections

mBio, 2015
Clostridium difficile is a leading cause of antibiotic-associated diarrhea, a significant animal pathogen, and a worldwide public health burden. Most disease-causing strains secrete two exotoxins, TcdA and TcdB, which are considered to be the primary ...
G. Carter, Anjana Chakravorty, Tu Anh Pham Nguyen, Steven J. Mileto, F. Schreiber, Lucy Li, P. Howarth, S. Clare, Bliss A. Cunningham, S. Sambol, Adam K Cheknis, I. Figueroa, Stuart Johnson, D. Gerding, J. Rood, G. Dougan, T. Lawley, D. Lyras   +17 more
semanticscholar   +1 more source

The role of a sequencing-based clinical intestinal screening test in patients at high-risk for Clostridium difficile and other pathogens: a case report

Journal of Medical Case Reports, 2019
Background Hospitalization and antibiotic treatment can put patients at high risk for Clostridium difficile infection, where a disturbance of the gut microbiome allows for Clostridium difficile proliferation and associated symptoms, including mild ...
Maureen Hitschfeld, Elena Tovar, Sarah Gupta, Elisabeth M. Bik, Christina Palmer, Michael C. Hoaglin, Daniel E. Almonacid, Jessica Richman, Zachary S. Apte   +8 more
doaj   +1 more source

Incidence of acute intestinal infections in Saint Petersburg during COVID-19 pandemic

Журнал инфектологии, 2022
The results of a study of modern epidemiological and characteristics of acute intestinal infections against the backdrop of the COVID-19 pandemic are presented.
T. V. Potapova, K. D. Ermolenko, A. V. Kholin, A. V. Stalevskaya, S. A. Gordeeva, I. V. Razdyakonova   +5 more
doaj   +1 more source

Incidence and Costs of Clostridium difficile Infections in Canada

Open Forum Infectious Diseases, 2015
CDI has a substantial epidemiologic, and economic, burden; and the largest proportion of costs arise from prolonged hospitalization. Interventions reducing the severity of infection and/or relapses requiring rehospitalization are likely to have the ...
A. Levy, S. Szabo, G. Lozano-Ortega, E. Lloyd-Smith, V. Leung, Robin Lawrence, M. Romney   +6 more
semanticscholar   +1 more source

Restrictive antibiotic stewardship associated with reduced hospital mortality in gram-negative infection [PDF]

, 2017
Introduction: Antimicrobial stewardship has an important role in the control of Clostridium difficile infection (CDI) and antibiotic resistance. An important component of UK stewardship interventions is the restriction of broad-spectrum beta-lactam ...
Helps, Alieen, Irvine, Sharon C., Jones, Brian L., Ritchie, Neil D., Robb, Fiona, Seaton, R. Andrew   +5 more
core   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

Advanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang, Dongjie Ye, Linqing Wu, Jiayu Liu, Banglun Pan, Zhu Zhang, Xiaoxia Zhang, Yuxin Yao, Nanhong Tang   +8 more
wiley   +1 more source

Association of tcdB PCR Cycle Threshold with Toxin Antigen Positivity and Clinical Severity in Clostridioides difficile Infection

Korean Journal of Clinical Laboratory Science
Various methods are used to diagnose and evaluate the severity of a Clostridioides difficile infection (CDI). Among them, the correlation between the tcdB gene PCR cycle threshold (Ct) values and toxin antigen detection is a key area of research.
Chan Kyu KIM, Ho-Keun CHOI
doaj   +1 more source

CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE IN THE NEUROINTENSIVECARE UNIT.

Frontiers in Neurology, 2013
. BACKGROUND- Critically ill patients are at high risk for acquiring Clostridium difficile infection. The aim of this study was to investigate the prevalence, severity and outcome of Neurointensive Care Unit (NICU) acquired Clostridium difficile ...
Swagata eTripathy, Priya eNair, Michael eRothburn, Michael eRothburn   +3 more
doaj   +1 more source

Burden of Clostridium difficile infection in the United States.

New England Journal of Medicine, 2015
BACKGROUND The magnitude and scope of Clostridium difficile infection in the United States continue to evolve. METHODS In 2011, we performed active population- and laboratory-based surveillance across 10 geographic areas in the United States to ...
F. Lessa, Yi Mu, Wendy M. Bamberg, Z. Beldavs, G. Dumyati, J. Dunn, M. Farley, S. Holzbauer, J. Meek, Erin C. Phipps, L. Wilson, L. Winston, Jessica a. Cohen, B. Limbago, S. Fridkin, D. Gerding, L. McDonald   +16 more
semanticscholar   +1 more source