Results 51 to 60 of about 118,981 (359)

Discovery and Biosynthesis of Celluxanthenes, Antibacterial Arylpolyene Alkaloids From Diverse Cellulose‐Degrading Anaerobic Bacteria

open access: yesAngewandte Chemie, EarlyView.
The structure and biosynthetic origin of the enigmatic “yellow affinity substance” (YAS) from the anaerobe thermophile Clostridium thermocellum (now: Acetivibrio thermocellus) were elucidated. YAS is a complex of unusual antibacterial arylpolyene alkaloids (celluxanthenes) that are produced by various cellulolytic anaerobes.
Keishi Ishida   +9 more
wiley   +2 more sources

Clostridium difficile Infection Worsens the Prognosis of Ulcerative Colitis

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2014
BACKGROUND: The impact of Clostridium difficile infections among ulcerative colitis (UC) patients is well characterized. However, there is little knowledge regarding the association between C difficile infections and postoperative complications among UC ...
María E Negrón   +11 more
doaj   +1 more source

Parasite infection in a cell population with deaths and reinfections [PDF]

open access: yesarXiv, 2021
We introduce a model of parasite infection in a cell population, where cells can be infected, either at birth through maternal transmission, from a contact with the parasites reservoir, or because of the parasites released in the cell medium after the lyses of infected cells.
arxiv  

Conjugated Lithocholic Acid Activates Hepatic TGR5 to Promote Lipotoxicity and MASLD‐MASH Transition by Disrupting Carnitine Biosynthesis

open access: yesAdvanced Science, EarlyView.
Takeda G protein‐coupled receptor 5 (TGR5) serves as a central regulator in the metabolic dysfunction‐associated steatotic liver disease (MASLD)/metabolic dysfunction‐associated steatohepatitis (MASH) transition via conjugated lithocholic acid (LCA). Mechanistically, TGR5 orchestrates lipotoxicity‐induced cell death through its interaction with CD36 ...
Senlin Lian   +10 more
wiley   +1 more source

Epidemiological analysis of bacterial food poisonings in Poland in 2005-2015

open access: yesJournal of Education, Health and Sport, 2017
Background. Bacterial poisoning is still considered as a major problem in polish society. Epidemiological analysis enables an update of the current status of its etiological agent.
Łukasz Świerszcz   +3 more
doaj   +3 more sources

Catch, Cut, or Block? Versatile 4‐N‐Derivatized Sialyl Glycosides for Influenza Virus Neuraminidase Detection and Purification

open access: yesAngewandte Chemie, EarlyView.
Sialyl glycosides containing 4‐N‐derivatized sialic acids synthesized by a highly efficient one‐pot two‐enzyme (OP2E) chemoenzymatic sialylation strategy have been shown to be versatile probes. They can resist sialidase cleavage, be selective substrates by influenza sialidases, or be nanomolar substrate analog‐based inhibitors and affinity ligands ...
Yue Yuan   +6 more
wiley   +2 more sources

Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins. [PDF]

open access: yes, 2018
Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic, neurologic and intestinal infections in humans and animals. The major toxins involved in diseases are alpha (CPA), beta (CPB), epsilon (ETX), iota (ITX), enterotoxin (
McClane, Bruce A   +2 more
core   +3 more sources

Aging‐induced Alternation in the Gut Microbiota Impairs Host Antibacterial Defense

open access: yesAdvanced Science, Volume 12, Issue 12, March 27, 2025.
Bacterial infections in older individuals often result in worse outcomes, but the mechanisms remain unclear. This study reveals that aging‐induced alterations in gut microbiota impair host antibacterial defense mechanisms, and exacerbate the consequences of bacterial infections.
Peng Gu   +20 more
wiley   +1 more source

Surveillance of Clostridium difficile infection during the period 2008-2009 in Rho hospital

open access: yesMicrobiologia Medica, 2011
Clostridium difficile is a Gram positive bacillus, anaerobic, sporogenous, with oro-faecal transmission. The formation of the spores can persist in a long time, encouraging the transmission.
Cristina Rescaldani   +4 more
doaj   +1 more source

PDE model for multi-patch epidemic models with migration and infection-age dependent infectivity [PDF]

open access: yesarXiv, 2023
We study a stochastic epidemic model with multiple patches (locations), where individuals in each patch are categorized into three compartments, Susceptible, Infected and Recovered/Removed, and may migrate from one patch to another in any of the compartments.
arxiv  

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