Results 51 to 60 of about 966,359 (290)

Structural and Functional Siderophore Remodeling by Enzymatic Delipidation

Angewandte Chemie, EarlyView.
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog, Keishi Ishida, Evelyn M. Molloy, Ron Hermenau, Kirstin Scherlach, Christian Hertweck   +5 more
wiley   +2 more sources

Clostridium difficile Infection Worsens the Prognosis of Ulcerative Colitis

Canadian Journal of Gastroenterology and Hepatology, 2014
BACKGROUND: The impact of Clostridium difficile infections among ulcerative colitis (UC) patients is well characterized. However, there is little knowledge regarding the association between C difficile infections and postoperative complications among UC ...
María E Negrón, Herman W Barkema, Kevin Rioux, Jeroen De Buck, Sylvia Checkley, Marie-Claude Proulx, Alexandra Frolkis, Paul L Beck, Levinus A Dieleman, Remo Panaccione, Subrata Ghosh, Gilaad G Kaplan   +11 more
doaj   +1 more source

Application of MALDI-TOF MS to assess clinical characteristics, risk factors, and outcomes associated with anaerobic bloodstream infection: a retrospective observational study

Annals of Clinical Microbiology and Antimicrobials, 2021
Background Correctly identifying anaerobic bloodstream infections (BSIs) is difficult. However, a new technique, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), enables more accurate identification and ...
Tsuyoshi Watanabe, Yuki Hara, Yusuke Yoshimi, Waka Yokoyama-kokuryo, Yoshiro Fujita, Masamichi Yokoe, Yoshinori Noguchi   +6 more
doaj   +1 more source

Incidence of acute intestinal infections in Saint Petersburg during COVID-19 pandemic

Журнал инфектологии, 2022
The results of a study of modern epidemiological and characteristics of acute intestinal infections against the backdrop of the COVID-19 pandemic are presented.
T. V. Potapova, K. D. Ermolenko, A. V. Kholin, A. V. Stalevskaya, S. A. Gordeeva, I. V. Razdyakonova   +5 more
doaj   +1 more source

Clostridium difficile Infection

Clinical and Translational Gastroenterology, 2015
Clostridium difficile infection (CDI) affects a broad population and has become so widespread the Centers for Disease Control and Prevention rated C. difficile as an urgent threat in 2013.1, 2 Recent basic-science research has focused on understanding the pathogenesis of the disease and alterations in the microbiome causing susceptibility.
openaire   +2 more sources

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang, Ao Peng, Shuaiqiang Li, Yaning Huang, Jian Yan, Leyuan Wang, Zhihui Zhu, Fei‐Long Liu, Erbao Bian, Yang Liu, Dasheng Tian, Fenghe Li, Qi Liu   +12 more
wiley   +1 more source

Extraintestinal Clostridium difficile Infections [PDF]

Clinical Infectious Diseases, 2013
 Clostridium difficile causes diarrhea that ranges from a benign, self-limiting antibiotic use-associated disease to a life-threatening pseudomembranous colitis. Clostridium difficile has rarely been isolated in extraintestinal infections. Our objective was to characterize clinical features and risk factors of these infections.
Mattila Eero, Tarkka Eveliina, Arkkila Perttu, Mattila Petri S., Tissari Päivi, Anttila Veli-Jukka, Mattila Eero, Tarkka Eveliina, Arkkila Perttu, Mattila Petri S., Tissari Päivi, Anttila Veli-Jukka   +11 more
openaire   +2 more sources

Exploring the potential of cold plasma therapy in treating bacterial infections in veterinary medicine: opportunities and challenges

Frontiers in Veterinary Science, 2023
Cold plasma therapy is a novel approach that has shown significant promise in treating bacterial infections in veterinary medicine. Cold plasma possesses the potential to eliminate various bacteria, including those that are resistant to antibiotics ...
Parvin Mohseni, Abozar Ghorbani, Niloofar Fariborzi   +2 more
doaj   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Prevalence of Infection in Patients After Radical Cystectomy and Neoadjuvant Chemotherapy

Bladder Cancer, 2017
Background and Objectives: Clostridium Difficile is the most common cause of nosocomial infectious diarrhea. This study evaluates the prevalence and predictors of Clostridium Difficile infections in patients undergoing radical cystectomy with or without ...
Katherine J. Cotter, Yunhua Fan, Gretchen K. Sieger, Christopher J. Weight, Badrinath R. Konety   +4 more
doaj   +1 more source