Results 81 to 90 of about 118,981 (359)
The Challenge of Clostridium difficile Infection [PDF]
Clostridium difficile infection is a major problem in the United States, resulting in significant morbidity, mortality, and financial costs to the health care system. This commentary provides an update regarding the epidemiology, diagnosis, current recommended management, and challenges surrounding C. difficile infection.
David C. Olson, Martin Scobey
openaire +3 more sources
Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen+9 more
wiley +1 more source
Clostridium subterminale is an anaerobic spore-forming bacterium usually associated with infections in patients who are immunocompromised. This case report focuses on a rare presentation of a multifascial space odontogenic infection associated with the ...
Karin Davis+4 more
doaj
Introduction Clostridium difficile is a Gram-positive bacillus, anaerobic, sporogenous ,with oro-faecal transmission.The formation of the spores can persist in a long time, encouraging the transmission.
David Usiglio+10 more
doaj +1 more source
Protective Microbiota: From Localized to Long-Reaching Co-Immunity [PDF]
Resident microbiota do not just shape host immunity, they can also contribute to host protection against pathogens and infectious diseases. Previous reviews of the protective roles of the microbiota have focused exclusively on colonization resistance ...
Abt+238 more
core +3 more sources
Engineered Tissue Models to Decode Host–Microbiota Interactions
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio+5 more
wiley +1 more source
Antimicrobial resistance and use, and rates of hospitalization associated with bacterial infections, including sepsis [PDF]
While the mechanisms and quantitative details are complex, few analysts would doubt that antibiotic use increases the prevalence of drug-resistant bacterial pathogens among all bacteria causing disease in a population. The causal connection between antibiotic use and the total incidence of severe bacterial infections, possibly mediated by antibiotic ...
arxiv
The Microbiota of the Extremely Preterm Infant. [PDF]
Colonization of the extremely preterm infant's gastrointestinal tract and skin begins in utero and is influenced by a variety of factors, the most important including gestational age and environmental exposures. The composition of the intestinal and skin
Sohn, Kristin, Underwood, Mark A
core +1 more source
Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe+5 more
wiley +1 more source
Modelling diverse sources of Clostridium difficile in the community: importance of animals, infants and asymptomatic carriers [PDF]
Clostridium difficile infections (CDIs) affect patients in hospitals and in the community, but the relative importance of transmission in each setting is unknown. We developed a mathematical model of C. difficile transmission in a hospital and surrounding community that included infants, adults, and transmission from animal reservoirs.
arxiv