Results 11 to 20 of about 67,472 (271)

Structures of a synthetic antibody selected against and bound to the C-terminal domain of Clostridium perfringens enterotoxin. [PDF]

Protein Sci
Abstract Clostridium perfringens enterotoxin (CpE) causes cytotoxic gastrointestinal disease in mammalian epithelium by binding membrane protein receptors called claudins. Claudins direct the formation of cell/cell tight junctions through oligomerization and govern the transport of molecules between individual cells.
Ogbu CP, Goldbach NM, Pacesa M, Kapoor S, Correia BE, Vecchio AJ.   +5 more
europepmc   +2 more sources

Pathogenicity and virulence of Clostridium perfringens [PDF]

Virulence, 2021
Clostridium perfringens is an extremely versatile pathogen of humans and livestock, causing wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis (including one of the most common human food-borne illnesses), and enterotoxemia (where toxins produced in the intestine are absorbed and damage distant organs such as the ...
Gohari, Iman Mehdizadeh, Navarro, Mauricio A, Li, Jihong, Shrestha, Archana, Uzal, Francisco, McClane, Bruce A   +5 more
openaire   +6 more sources

Transformation of Clostridium perfringens [PDF]

Journal of Bacteriology, 1984
Clostridium perfringens 11268 CDR (Rifr Tcs), the strain transformed in our experiments, was generated by curing a spontaneous, rifampicin-resistant mutant of C. perfringens 11268 (Rifr Tcr). High-temperature growth yielded tetracycline-sensitive, rifampicin-resistant cells which no longer contained pCW3, a 42.8-kilobase plasmid.
Michael Yarus, C H Squires, B J Kopp, R J Evans, D L Heefner   +4 more
openaire   +2 more sources

Real-Time PCR for direct detection of Clostridium perfringens from horse with enterocolitis infection

Kufa Journal for Veterinary Medical Sciences, 2016
Clostridium perfringens is one of the most important causative agents of enterocolitis infection in horses. This bacterium capable to produce potential enterotoxin that cause  diarrhea in  horses.
Jabbar A. Alwan, Ali A. Al-zaidy, Kadhim H. Abbas   +2 more
doaj   +1 more source

Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases : a review on bovine necro-haemorrhagic enteritis [PDF]

, 2017
Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized by sudden death associated with small ...
Deprez, Piet, Ducatelle, Richard, Goossens, Evy, Haesebrouck, Freddy, Pardon, Bart, Valgaeren, Bonnie, Van Immerseel, Filip   +6 more
core   +3 more sources

Toxin-neutralizing antibodies protect against Clostridium perfringens-induced necrosis in an intestinal loop model for bovine necrohemorrhagic enteritis [PDF]

, 2016
Background: Bovine necrohemorrhagic enteritis is caused by Clostridium perfringens type A. Due to the rapid progress and fatal outcome of the disease, vaccination would be of high value. In this study, C.
Deprez, Piet, Ducatelle, Richard, Goossens, Evy, Haesebrouck, Freddy, Pardon, Bart, Rodrigo, Diego, Schauvliege, Stijn, Timbermont, Leen, Valgaeren, Bonnie, Van Immerseel, Filip, Verherstraeten, Stefanie   +10 more
core   +2 more sources

Black Urine and Methemoglobinemia in the Setting of Sepsis Due to Clostridium Perfringens

Clinical Medicine Insights: Case Reports, 2020
Clostridium Perfringens is an anaerobic gram-positive bacillus able to produce different types of toxins and can cause septicemia. The mechanism is through translocation from a previously colonized gastrointestinal or genital tract. Massive intravascular
Salwa A Koubaissi, Reem G Al Assaad, Ziad Itani, Imad Bouakl   +3 more
doaj   +1 more source

Research Note: Prevalence and molecular characteristics of Clostridium perfringens in “no antibiotics ever” broiler farms

Poultry Science, 2021
: Clostridium perfringens (C. perfringens) is the etiological agent of necrotic enteritis and gangrenous dermatitis; 2 diseases that cause significant economic and welfare concerns to the broiler industry.
Courtney A. Fancher, Hudson T. Thames, Mary G. Colvin, Li Zhang, Nikhil Nuthalapati, Aaron Kiess, Thu T.N. Dinh, Anuraj T. Sukumaran   +7 more
doaj   +1 more source

The C-terminal domain of Clostridium perfringens alpha toxin as a vaccine candidate against bovine necrohemorrhagic enteritis [PDF]

, 2016
Bovine necrohemorrhagic enteritis is caused by Clostridium perfringens and leads to sudden death. Alpha toxin, together with perfringolysin O, has been identified as the principal toxin involved in the pathogenesis.
Deprez, Piet, Ducatelle, Richard, Goossens, Evy, Haesebrouck, Freddy, Pardon, Bart, Rodrigo, Diego, Schauvliege, Stijn, Timbermont, Leen, Valgaeren, Bonnie, Van Immerseel, Filip, Verherstraeten, Stefanie   +10 more
core   +4 more sources

Intravascular Hemolysis and Septicemia due to Clostridium perfringens Emphysematous Cholecystitis and Hepatic Abscesses

Case Reports in Medicine, 2015
Context. Clostridium perfringens septicemia is often associated with translocation from the gastrointestinal or gastrourinary tract and occurs in patients who have malignancy or are immunocompromised.
Justin Cochrane, Lacie Bland, Mary Noble
doaj   +1 more source