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Discitis due to Clostridium perfringens
Joint Bone Spine, 2008A combination of disk space narrowing and vacuum phenomenon on radiographs of the spine is usually considered a reliable indicator of degenerative disk disease. We report a case in which vacuum phenomenon was related to Clostridium perfringens discitis.A 79-year-old woman was admitted for inflammatory low back pain that had worsened steadily over the ...
Yves Domart +5 more
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Clostridium perfringens vaccines
Vaccine, 2009Both Clostridium perfringens spores and toxins have reportedly been considered as a biological warfare agents. The spores may be incorporated into weapons which cause traumatic injury, and the resulting delivery of spores deep into tissues would result in the development of gas gangrene. Of the C.
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CLOSTRIDIUM PERFRINGENS ENTEROTOXIN1
Journal of Milk and Food Technology, 1971Clostridium perfringens type A food poisoning is caused by ingestion of food contaminated with large numbers of C. perfringens cells. The cells multiply and sporulate in the intestine and produce an enterotoxin in situ. The enterotoxin is released upon cell lysis and causes increased capillary permeability, vasodilation, and excess fluid movement into ...
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Clostridium perfringens: toxinotype and genotype
Trends in Microbiology, 1999Clostridium perfringens is a ubiquitous pathogen that produces many toxins and hydrolytic enzymes. Because the toxin-encoding genes can be located on extrachromosomal elements or in variable regions of the chromosome, several pathovars have arisen, each of which is involved in a specific disease.
Maryse Gibert +2 more
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Clostridium perfringens emphysematous cystitis
Urology, 1993Emphysematous cystitis is a rare disease and is usually caused by aerobic bacteria, most commonly Escherichia coli. Only rarely have anaerobic bacteria been associated with this condition. We report a case of emphysematous cystitis due to Clostridium perfringens with bacteremia in an elderly diabetic woman.
Burke A. Cunha +2 more
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Clostridium perfringens Corneal Ulcer
Archives of Ophthalmology, 1979A corneal ulcer caused by Clostridium perfringens developed in a 76-year-old woman with Sjögren's syndrome. Experimental C perfringens keratitis was induced in rabbits by the intrastromal injection of 10(7) organisms. In both our patient and the experimental animals, a bullous lesion overlay the affected area of the cornea.
G A Stern, B L Hodes, E L Stock
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Virulence Factors of Clostridium perfringens [PDF]
Clinical Infectious Diseases, 1979 Clostridium perfringens produces a variety of virulence factors. The mechanism of action of these factors usually falls into one of three groups. Some of these virulence factors, such as the alpha toxin, which is phospholipase C, and the kappa toxin, which is a collagenase, are enzymes that hydrolyze substances essential to the integrity of membranes ...
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An overview of Clostridium perfringens enterotoxin
Toxicon, 1996Clostridium perfringens enterotoxin (CPE) is considered to be the virulence factor responsible for causing the symptoms of C. perfringens type A food poisoning and may also be involved in other human and veterinary illnesses. CPE has a unique four-step membrane action that apparently involves: (1) CPE binding to a 50,000 mol.
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Ribonucleoprotein of Clostridium perfringens (BP6K)
Archives of Biochemistry and Biophysics, 1953Abstract A procedure has been presented for the isolation and purification of the ribonucleoprotein from lyophilized Clostridium perfringens (BP6K) cells. Separation of the ribonucleoprotein from the desoxyribonucleoprotein was effected by extracting the lyophilized cells with 0.14 M NaCl. The amino acid composition of the purified nucleoprotein was
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The enteric toxins of Clostridium perfringens
2004The Gram-positive pathogen Clostridium perfringens is a major cause of human and veterinary enteric disease largely because this bacterium can produce several toxins when present inside the gastrointestinal tract. The enteric toxins of C. perfringens share two common features: (1) they are all single polypeptides of modest (approximately 25-35 kDa ...
Derek J. Fisher +4 more
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