Results 91 to 100 of about 1,838,863 (339)
While scholars generally use the concept of transfictionality to describe narrative crossover between separate works, this limitation does not apply in the eighteenth century, when publication in multiple installments and evolving ideas about the concept
Benjamin H. Baker
doaj +1 more source
In biological systems, closure refers to a holistic feature such that their constitutive processes, operations and transformations (1) depend on each other for their production and maintenance and (2) collectively contribute to determine the conditions at which the whole organization can exist.
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Closure Device-Related Thrombosis After Anticoagulation With Dabigatran in Patients Undergoing Percutaneous Left Atrial Appendage Closure: Case Reports and Literature Review [PDF]
Xiaoye Li, Qinchun Jin, Xiaochun Zhang
openalex +1 more source
FUZZY CLOSURE SYSTEMS AND FUZZY CLOSURE OPERATORS
Summary: We introduce fuzzy closure systems and fuzzy closure operators as extensions of closure systems and closure operators. We study relationships between fuzzy closure systems and fuzzy closure spaces. In particular, two families \(F(S)\) and \(F(C)\) of fuzzy closure systems and fuzzy closure operators on \(X\) are complete lattice isomorphic.
Kim, Yong Chan, Ko, Jung Mi
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Tight closure, plus closure and Frobenius closure in cubical cones [PDF]
This is a detailed analysis of tight closure, plus closure, Frobenius closure, and irreducibility of ideals in the ring \(R = K[[X,Y,Z]]/(X^3 + Y^3 + Z^3)\), where \(K\) is a field of characteristic \(p\) and \(p \not = 3\). The author uses the \(\mathbb{Z}_3\)-grading on this ring, and proves more generally that the tight closure of a homogeneous ...
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

