Results 101 to 110 of about 16,063 (299)

Equivariant closure operators and trisp closure maps

open access: yes, 2010
A trisp closure map ϕ is a special map on the vertices of a trisp (triangulated space) T with the property that T collapses onto the subtrisp induced by the image of ϕ. We study the interaction between trisp closure maps and group operations on the trisp,
Lehmann, Juliane
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Closure operators and choice operators : a survey

open access: yes, 2007
International audienceIn this talk I will give a overview on the connections between closure operators and choice operators and on related results. An operator on a finite set S is a map defined on the set P(S) of all the subsets of S. A closure operator
Monjardet, Bernard
core  

Closure operators and connectedness

open access: yes, 1994
This paper introduces the notion of connectedness with respect to a closure operator on a construct X. Many classical results about topological connectednedness are extended to this setting.
Hajek, D., Castellini, G.
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Closure operators in convergence spaces

open access: yes, 2000
We define two closure operators of some well-known topological categories and investigate the relationships between these closure operators and the one that is given in [9].
Baran, Mehmet
core   +1 more source

From torsion theories to closure operators and factorization systems [PDF]

open access: yesCategories and General Algebraic Structures with Applications, 2020
Torsion theories are here extended to categories equipped with an ideal of 'null morphisms', or equivalently a full subcategory of 'null objects'. Instances of this extension include closure operators viewed as generalised torsion theories in a 'category
Marco Grandis, George Janelidze
doaj  

Dynamics of Resource Closure Operators [PDF]

open access: yes, 2009
We propose a framework for managing resources via convergent operators. Operators represent their need for a resource to a designated resource closure operator that manages the resource. We evaluate a specific design for a resource closure operator by simulation and demonstrate that the operator achieves a near-optimal balance between cost and value ...
Alva L. Couch, Marc Chiarini
openaire   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Dual closure operators and their applications

open access: yes, 2020
Departing from a suitable categorical description of closure operators, this paper dualizes this notion and introduces some basic properties of dual closure operators. Usually these operators act on quotients rather than subobjects, and much attention is
W Tholen, D Dikranjan
core  

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