Results 51 to 60 of about 182,956 (311)

Analysis of Blood Stasis for Stent Thrombosis Using an Advection-Diffusion Lattice Boltzmann Scheme

Mathematics
An advection-diffusion solver was applied to assess how stent strut shape and position impact the development of a pro-thrombotic region within the stented human artery.
Ruben van der Waerden, James Spendlove, James Entwistle, Xu Xu, Andrew Narracott, Julian Gunn, Ian Halliday   +6 more
doaj   +1 more source

Platelet Phenotype and Function in the Setting of Pediatric Extracorporeal Membrane Oxygenation (ECMO): A Systematic Review

Frontiers in Cardiovascular Medicine, 2019
Background: Despite increasing technical improvement and extracorporeal membrane oxygenation (ECMO)-related knowledge over the past three decades, morbidity and mortality associated with bleeding and clotting complications remain high in pediatric ...
Hui Ping Yaw, Hui Ping Yaw, Suelyn Van Den Helm, Graeme MacLaren, Graeme MacLaren, Graeme MacLaren, Graeme MacLaren, Matthew Linden, Paul Monagle, Paul Monagle, Paul Monagle, Vera Ignjatovic, Vera Ignjatovic   +12 more
doaj   +1 more source

Detection of clot formation & lysis In-Vitro using high frequency photoacoustic imaging & frequency analysis

Photoacoustics, 2023
Clotting is a physiological process that prevents blood loss after injury. An imbalance in clotting factors can lead to lethal consequences such as exsanguination or inappropriate thrombosis.
Filip J. Bodera, Mark J. McVey, Krishnan Sathiyamoorthy, Michael C. Kolios   +3 more
doaj   +1 more source

CLOTTING ABNORMALITIES IN CHRONIC LIVER-DISEASE

, 1992
In patients with chronic liver disease (CLD), several clotting changes can be observed. The most frequent abnormality is the reduced synthesis of many clotting factors, including vitamin-K-dependent and vitamin-K-independent ones. A low platelet count is
FERRO, Domenico, Mirella Saliola, Claudio Quintarelli, Francesco Balsano, VIOLI, Francesco, Corrado Cordova   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The battle of the clot

Cleveland Clinic Journal of Medicine, 2009
In this issue we review two situations in which low-molecular-weight heparins have special advantages: in pregnant women and in patients with cancer.
openaire   +2 more sources

The clot thickens [PDF]

Kidney International, 2006
Vascular sclerosis has been linked to many risk factors, including smoking, family history, low birth weight, and hypertension. In interesting studies, Goforth et al. show an increased rate of mutations in thrombophilic molecules in patients with vascular sclerosis in renal biopsies, suggesting yet another mechanism.
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source