Results 141 to 150 of about 5,910,870 (299)
Interaction of hirudin with thrombin: identification of a minimal binding domain of hirudin that inhibits clotting activity [PDF]
[[abstract]]Hirudin, isolated from the European leech Hirudo medicinalis, is a potent inhibitor of thrombin, forming an almost irreversible thrombin-hirudin complex.
Mao SJT;Yates MT;Owen TJ;Krstenansky JL
core
Background Milk clotting enzymes, essential for milk coagulation in cheese production, are obtained from the stomach of young ruminants, an expensive and limited source. This study was accomplished by finding a suitable alternative.
Eman A. Karam +4 more
doaj +1 more source
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang +11 more
wiley +1 more source
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He +10 more
wiley +1 more source
Different from intensively used anticoagulant heparin, hirudin as a representative of natural bio-molecular inhibitors can form specific hirudin-thrombin complex and function as a serine proteinase to efficiently prevent blood coagulation with less ...
Liu, Fu +6 more
core
Reagent-specific underestimation of turoctocog alfa pegol (N8-GP) clotting activity owing to decelerated activation by thrombin. [PDF]
Persson E, Foscolo T, Hansen M.
europepmc +1 more source
Mutagenesis by UV and Nitrous Acid for increase of rennet production in Rhizomucor miehei
Introduction : In this study, Mutation and Selection technique was used to increase production of Rennet (milk clotting enzyme) in Rhizomucor miehei. Mutation and Selection is a technique for microbial strain improvement in which, mutation is induced on ...
Naser Tajik +3 more
doaj
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Biochemical characterization of a semi-purified aspartic protease from sea catfish Bagre panamensis with milk-clotting activity. [PDF]
Osuna-Ruiz I +6 more
europepmc +1 more source
Aqueous extract of Lippia nodiflora possessed anti-inflammatory activity in Carrageenan induced mice paw edema in both doses 100 and 200 mg /kg bw (P< 0.01). However, the ethanolic extracts didn’t induced anti-inflammatory effects in both doses. Aqueous
Ali Esmail Al-Snafi
doaj

