Results 251 to 260 of about 5,910,870 (299)

High-Level Expression and Substrate-Binding Region Modification of a Novel BL312 Milk-Clotting Enzyme To Enhance the Ratio of Milk-Clotting Activity to Proteolytic Activity

Journal of Agricultural and Food Chemistry, 2019
A novel BL312 milk-clotting enzyme (MCE) exhibited high-level expression and remarkable milk-clotting activity (MCA) (865 ± 20 SU/mL) that was 3.3-fold higher than the control by optimizing induction conditions in recombinant Escherichia.
Yongjun Xia, Na Zhang, Lianzhong Ai
exaly   +2 more sources

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CLOTTING AND FIBRINOLYTIC ACTIVITIES IN PERITONEAL FLUID

BJOG: An International Journal of Obstetrics & Gynaecology, 1981
SummaryPeritoneal fluid does not clot spontaneously on collection, due to a lack of prothrombin activation, consequent upon a virtual absence of factors V and VIII. Factor VIII related antigen is present in peritoneal fluid in only very small amounts, suggesting that this factor is excluded from the peritoneal cavity, probably by virtue of its size ...
H A, Pattinson, P R, Koninckx, I A, Brosens, J, Vermylen   +3 more
openaire   +2 more sources

Activated Clotting Time (ACT)

2013
The standard assay for monitoring anticoagulation during extracorporeal life support (ECLS) is the activated clotting time (ACT) test, with celite, kaolin, and glass beads being the most commonly used activators to initiate contact activation. The point-of-care ACT test has been the preferred test in catheterization labs and cardiac theatres because it
Stephen, Horton, Simon, Augustin
openaire   +2 more sources

Activation of Clotting Factors in Cancer

2009
Evidence for ‘‘hypercoagulability’’ is commonly found in patients with cancer and increases the risk of thromboembolism (TE) [1].While the pathophysiology of TE in cancer is complex, it can be viewed classically as related to abnormalities of Virchow’s triad: stasis of the blood; vascular injury; hypercoagulability (or, as described by Virchow himself,
Frederick R, Rickles, Anna, Falanga
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Platelets and Surface‐Mediated Clotting Activity

British Journal of Haematology, 1979
Summary. In contrast to previously reported studies, no evidence could be adduced for the activation of Hageman factor (factor XII) by platelets, whether or not these cells had been incubated with adenosine diphosphate (ADP).
W J, Vicic, O D, Ratnoff, H, Saito, G H, Goldsmith   +3 more
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BLOOD CLOTTING ACTIVATION DURING NORMAL PREGNANCY

Thrombosis Research, 1996
Pregnancy is considered as a hypercoagulable state and an increased incidence of thromboembolic phenomena has been reported in pregnant women. Relevant changes in the hemostatic mechanism have been reported during physiological pregnancy: briefly, increased levels of coagulation factors, enhanced thrombin generation and suppression of fibrinolysis are ...
P. Comeglio, FEDI, SANDRA, A.A. Liotta, A.P. Cellai, CHIARANTINI, ELENA, PRISCO, DOMENICO, F. Mecacci, PARRETTI, ELENA, MELLO, GIORGIO, ABBATE, ROSANNA   +9 more
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Emicizumab does not interfere with the activated clotting time

Haemophilia, 2022
AbstractIntroductionThe activated clotting time (ACT) is a useful marker of unfractionated heparin (UFH) activity during cardiopulmonary bypass (CPB) or cardiac catheterization. Emicizumab, recently approved for bleeding prevention in haemophilia A patients, acts like FVIII but does not need prior activation; it therefore shortens coagulation times in ...
Capdevila, Ladislas, Frère, Corinne, Desvages, Maximilien, Harroche, Annie, Bally, Cécile, Abbes, Ahmed, d'Oiron, Roseline, Frenzel, Laurent, Borgel, Delphine, Lasne, Dominique   +9 more
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Platelet Activity and Activation of Blood Clotting by Glass

Thrombosis and Haemostasis, 1960
SummaryThrough an investigation of the influence of platelet activity on the initiation of clotting by glass contact the following results were obtained:1. There was no correlation between platelet count and platelet activity in centrifuged plasma.2. When platelet-rich plasma was treated by excess of powdered glass the activated “foreign surface factor“
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Factor VIII clotting activity

1992
Factor VIII activity has been historically measured with two types of methods: the one-stage assay, based on the activated partial thromboplastin time (APTT) (Chapter 5) and the two-stage assay, based on the thromboplastin generation test. The relative merits of the two assays have been debated1,2.
P. M. Mannucci, A. Tripodi
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