Results 41 to 50 of about 1,225 (164)

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Giant Cloud Condensation Nuclei enhanced Ice Sublimation Process: a potential mechanism in mixed-phase clouds [PDF]

Atmospheric Chemistry and Physics
The Wegener–Bergeron–Findeisen (WBF) process describes the growth of ice crystals at the expense of supercooled liquid droplets in mixed-phase clouds, driven by phase transitions at temperatures below 0 °C.
D. Ji, C. Ritter, X. Sun, M. Moser, M. Moser, C. Voigt, C. Voigt, M. Palm, J. Notholt   +8 more
doaj   +1 more source

Frequent new particle formation over the high Arctic pack ice by enhanced iodine emissions

Nature Communications, 2020
Which vapors are responsible for new particle formation in the Arctic is largely unknown. Here, the authors show that the formation of new particles at the central Arctic Ocean is mainly driven by iodic acid and that particles smaller than 30 nm in ...
Andrea Baccarini, Linn Karlsson, Josef Dommen, Patrick Duplessis, Jutta Vüllers, Ian M. Brooks, Alfonso Saiz-Lopez, Matthew Salter, Michael Tjernström, Urs Baltensperger, Paul Zieger, Julia Schmale   +11 more
doaj   +1 more source

Method to retrieve cloud condensation nuclei number concentrations using lidar measurements [PDF]

Atmospheric Measurement Techniques, 2019
Determination of cloud condensation nuclei (CCN) number concentrations at cloud base is important to constrain aerosol–cloud interactions. A new method to retrieve CCN number concentrations using backscatter and extinction profiles from multiwavelength ...
W. Tan, G. Zhao, Y. Yu, C. Li, J. Li, L. Kang, T. Zhu, C. Zhao   +7 more
doaj   +1 more source

AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration

Advanced Science, EarlyView.
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola, Keun‐Young Kim, Ziyao Shen, Guy A. Perkins, Muna Poudel, Yoonjin Lim, Hyejeong Choi, Soo‐Ho Choi, Mark H. Ellisman, Robert N. Weinreb, Won‐Kyu Ju   +10 more
wiley   +1 more source

Dust suppresses aerosol first indirect effects in marine warm clouds over the North Atlantic Ocean

Communications Earth & Environment
Mineral dust is one of the most abundant atmospheric aerosols, yet its role in aerosol-cloud interactions remains poorly constrained. Although aging during transport enables weakly hygroscopic dust to act as cloud condensation nuclei and modify cloud ...
Satyendra K. Pandey, Adeyemi A. Adebiyi, Yang Lian, V. Vinoj, Xue Zheng   +4 more
doaj   +1 more source

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source

Nucleation of atmospheric particles

EPJ Web of Conferences, 2009
Two types of particles exist in the atmosphere, primary and secondary particles. While primary particles such as soot, mineral dust, sea salt particles or pollen are introduced directly as particles into the atmosphere, secondary particles are formed in ...
Curtius J.
doaj   +1 more source

Context‐centric proactive information delivery for Knowledge Work support: Opportunities, challenges, and directions. An Annual Review of Information Science and Technology (ARIST) paper

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Context‐centric proactive information delivery (PID) is a relatively underexplored domain within recommender systems (RS) aimed at enhancing Knowledge Workers' productivity by proactively providing relevant information during digital tasks.
Mahta Bakhshizadeh, Christian Jilek, Markus Schröder, Heiko Maus, Andreas Dengel   +4 more
wiley   +1 more source

Description and evaluation of GLOMAP-mode: a modal global aerosol microphysics model for the UKCA composition-climate model [PDF]

Geoscientific Model Development, 2010
A new version of the Global Model of Aerosol Processes (GLOMAP) is described, which uses a two-moment pseudo-modal aerosol dynamics approach rather than the original two-moment bin scheme.
G. W. Mann, K. S. Carslaw, D. V. Spracklen, D. A. Ridley, P. T. Manktelow, M. P. Chipperfield, S. J. Pickering, C. E. Johnson   +7 more
doaj   +1 more source