Results 161 to 170 of about 96,379 (348)
Clozapine in the community [PDF]
British Journal of Psychiatry, 1992 Michael Phelan +2 more
openaire +3 more sources
Metabolic Syndrome Screening in Seriously Mentally Ill Patients: A Quality Improvement Project [PDF]
, 2016 A Project Submitted in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCE in Nursing ScienceSeriously mentally ill patients who are taking second-generation antipsychotics have a high risk of metabolic complications ...
Moreno, Annabel
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Obesity Reviews, EarlyView.ABSTRACT Introduction Although the physiologic alterations seen in obesity often affect the pharmacokinetics and pharmacodynamics of drugs, most clinical trials do not consider these aspects specifically for this population. To date, there is no list of potentially inappropriate medications for patients living with obesity. The aim of this study was to
Sarah Berdot +17 more
wiley +1 more source
Olanzapine Attenuates Cue-elicited Craving for Tobacco
, 2004 Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures
Hutchinson, Kent E +5 more
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The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
Obesity Reviews, EarlyView.ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin +6 more
wiley +1 more source
Psychiatry and Clinical Neurosciences, EarlyView.Schizophrenia is a complex psychiatric disorder characterized by positive, negative, and general psychopathological symptoms. While antipsychotic drugs are effective for positive symptoms, they provide limited benefit for negative symptoms, which are often persistent and strongly associated with functional disability.
Thiago Carnaval +6 more
wiley +1 more source
Commentary: the risks of enforcing clozapine therapy [PDF]
, 1999 Thomas R. E. Barnes
openalex +1 more source
Chemogenetics revealed: DREADD occupancy and activation via converted clozapine
Science, 2017 Juan L. Gomez +12 more
semanticscholar +1 more source
Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation
The Journal of Physiology, EarlyView.Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson +7 more
wiley +1 more source
Case report: Time response of plasma clozapine concentrations on cessation of heavy smoking
Frontiers in PharmacologySmoking cessation in patients treated with clozapine might lead to elevated plasma concentrations and severe side effects. This case report investigated the trajectory of clozapine plasma concentrations over time after smoking cessation in a Chinese ...
Lingyan Qi +5 more
doaj +1 more source