European Journal of Neuroscience, Volume 56, Issue 12, Page 6141-6161, December 2022., 2022 Chemical synapses are tiny and overcrowded environments enriched with thousands of protein species. Many efforts have been devoted to developing sensors and actuators able to evaluate and control synaptic communication. Most of these recent tools are based on the engineering of one or more specific synaptic proteins used to target active moieties to ...
Jacopo Lamanna +3 more
wiley +1 more source
Atypical antipsychotic therapy in Parkinson's disease psychosis: A retrospective study. [PDF]
, 2017 ObjectiveParkinson's disease psychosis (PDP) is a frequent complication of idiopathic Parkinson's disease (iPD) with significant impact on quality of life and association with poorer outcomes.
Bizzarri +29 more
core +2 more sources
Infections associated with clozapine: a pharmacovigilance study using VigiBase®
Frontiers in Pharmacology, 2023 Introduction: Clozapine is primarily reserved for treatment-resistant schizophrenia due to safety concerns associated with its use. Infections have been reported with clozapine, which may lead to elevated serum levels of the drug.
Basile Chrétien +11 more
doaj +1 more source
Striatal dopamine D2 receptor binding of risperidone in schizophrenic patients as assessed by 123I-iodobenzamide SPECT: a comparative study with olanzapine [PDF]
, 2002 The aim of this investigation was to compare the degree of striatal dopamine-(D2) receptor blockade by two atypical antipsychotic drugs, risperidone and olanzapine.
Arndt J +18 more
core +1 more source
Risk factors associated with 30‐day unplanned hospital readmission for patients with mental illness
International Journal of Mental Health Nursing, Volume 32, Issue 1, Page 30-53, February 2023., 2023 Abstract Unplanned hospital readmission rate is up to 43% in mental health settings, which is higher than in general health settings. Unplanned readmissions delay the recovery of patients with mental illness and add financial burden on families and healthcare services.
Huaqiong Zhou +3 more
wiley +1 more source
Change in plasma concentration of clozapine and norclozapine following a switch of oral formulation
Therapeutic Advances in Psychopharmacology, 2020 Background: Clozapine formulation has been shown to affect plasma concentrations of clozapine and norclozapine. Changes in formulation might result in toxicity or treatment failure.
Farinaz Keshavarzi +3 more
doaj +1 more source
A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]
, 2017 The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi +6 more
core +2 more sources
Clozapine Treatment Is Associated With Higher Prescription Rate of Antipsychotic Monotherapy and Lower Prescription Rate of Other Concomitant Psychotropics: A Real-World Nationwide Study [PDF]
, 2022 Background: Although clozapine is effective for treatment-resistant schizophrenia (TRS), the rate of clozapine prescription is still low. Whereas antipsychotic monotherapy is recommended in clinical practice guidelines, the rate of antipsychotic ...
Atake, Kiyokazu +35 more
core +1 more source
Общая реаниматология, 2019 Purpose: identification of pathological changes in the liver at early stages of the effect of clozapine and clozapine combined with ethanol to improve the diagnosis of this acute exposure.Materials and methods. The experiments were carried out on outbred
O. L. Romanova +5 more
doaj +1 more source
Sri Lanka Journal of Medicine, 2020 Clozapine is a second-generation antipsychotic used for treatment-resistant schizophrenia. Obsessive-compulsive symptoms induced by clozapine is a known entity.
Layani C. Rathnayake +2 more
doaj +1 more source