Results 41 to 50 of about 39,176 (275)
Evaluation of the effectiveness and acceptability of intramuscular clozapine injection:illustrative case series [PDF]
, 2020 Aims and method: A series of eleven patients prescribed intramuscular clozapine at five UK sites is presented. Using routinely collected clinical data, we describe the use, efficacy and safety of this treatment modality.
Henry, Rebecca +6 more
core +1 more source
Advanced Science, EarlyView.Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji +13 more
wiley +1 more source
Therapeutic Advances in Psychopharmacology, 2021 Background: People with schizophrenia have a 15–20-year reduction in life expectancy, driven in part by the metabolic effects of antipsychotics. Clozapine is associated with the highest rates of weight gain.
Jessica Spokes +6 more
doaj +1 more source
Leukopenia and agranulocytosis in atypical antipsychotic treatment - besides clozapine
European Psychiatry, 2021 Introduction Leukopenia and agranulocytosis are reported and dangerous haematological side-effects associated with the use of antipsychotics, mostly reported for clozapine administration.
B. Jorge +2 more
doaj +1 more source
Rapid Dose-Dependent Effect of Clozapine on a Schizophrenic Patient's Lipid Profile
, 2011 Clozapine is known to be associated with higher risk of metabolic syndrome, including dyslipidaemia, but the mechanisms of such a relationship are still under debate.
江惠綾;劉震鐘;黃宗正 +1 more
core +1 more source
Advanced Science, EarlyView.An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu +11 more
wiley +1 more source
Managing ciprofloxacin-clozapine interaction with immunoassay-based monitoring: A case report [PDF]
Mental Health ClinicianWhereas the interaction between clozapine and ciprofloxacin is well-documented, this case report emphasizes the importance of closely monitoring clozapine plasma concentrations during concurrent administration.
Kristin Waters, PharmD, BCPS, BCPP +4 more
doaj +1 more source
, 2014 Clozapine is the most effective antipsychotic for patients with treatment-refractory schizophrenia, but many adverse effects are noted. Clinicians usually hesitate to switch from clozapine to other antipsychotics because of the risk of a re-emergence or ...
林朝誠 +1 more
core +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Общая реаниматология, 2019 Purpose: identification of pathological changes in the liver at early stages of the effect of clozapine and clozapine combined with ethanol to improve the diagnosis of this acute exposure.Materials and methods. The experiments were carried out on outbred
O. L. Romanova +5 more
doaj +1 more source