Results 51 to 60 of about 91,871 (338)

Atypical antipsychotic therapy in Parkinson's disease psychosis: A retrospective study. [PDF]

, 2017
ObjectiveParkinson's disease psychosis (PDP) is a frequent complication of idiopathic Parkinson's disease (iPD) with significant impact on quality of life and association with poorer outcomes.
Bizzarri, Cummings, Fernandez, Fernandez, Fénelon, Gama, Goldman, Hack, Hubbard, Kiferle, Lertxundi, McFarland, Meltzer, Meral, Mesquita, Mocci, Munhoz, Noel, Pagonabarraga, Prohorov, Rabey, Reichmann, Rolland, Seppi, Shotbolt, Starkstein, Thomas, Vanover, Weintraub, Zhu   +29 more
core   +2 more sources

Leukopenia and agranulocytosis in atypical antipsychotic treatment - besides clozapine

European Psychiatry, 2021
Introduction Leukopenia and agranulocytosis are reported and dangerous haematological side-effects associated with the use of antipsychotics, mostly reported for clozapine administration.
B. Jorge, C. Pedro Fernandes, J. Carvalho   +2 more
doaj   +1 more source

The Impact of Metformin on Weight and Waist Circumference in Patients Treated With Clozapine: A One-Year Retrospective Cohort Study. [PDF]

Acta Psychiatr Scand
ABSTRACT Background Metformin shows potential in combating clozapine‐induced weight gain (CIWG). However, current evidence for its use remains limited. Through an audit we determined the prevalence of metformin use among clozapine‐treated patients and its impact on weight and waist circumference (WC).
Per BL, Loeser S, Edwards S, Lee WS, Wilton LR, Clark SR.   +5 more
europepmc   +2 more sources

Antipsychotic dose escalation as a trigger for Neuroleptic Malignant Syndrome (NMS): literature review and case series report [PDF]

, 2012
Background: “Neuroleptic malignant syndrome” (NMS) is a potentially fatal idiosyncratic reaction to any medication which affects the central dopaminergic system. Between 0.5% and 1% of patients exposed to antipsychotics develop the condition.
AL Pelonero, BD Berman, D Berardi, D Bereardi, D Heyland, Daniel J Smith, Daniel Martin, F-GB Pajonk, H Itoh, J Ananth, J Delay, J Gill, JF Patterson, JN Trollor, JR Strawn, Julie Langan, K Otani, KL Hall, LF Viejo, LS Friedman, M Dave, MJ Bhanushali, P Adnet, P Sachdev, P Sachdev, PE Keek, PF Buckley, PI Rosebush, PJ Alexander, Polash Shajahan, RJ Gurrera, RJ Gurrera, RW Baker, S Caroff, S Madakasira   +34 more
core   +3 more sources

Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits

Clinical and Translational Science, Volume 16, Issue 1, Page 62-72, January 2023., 2023
Abstract Clinical response of clozapine is closely associated with serum concentration. Although tobacco smoking is the key environmental factor underlying interindividual variability in clozapine metabolism, recent genome‐wide studies suggest that CYP1A and NFIB genetic variants may also be of significant importance, but their quantitative impact is ...
Hasan Çağın Lenk, Robert Løvsletten Smith, Kevin S. O'Connell, Marin M. Jukić, Marianne Kristiansen Kringen, Ole A. Andreassen, Magnus Ingelman‐Sundberg, Espen Molden   +7 more
wiley   +1 more source

Antipsychotic medication for childhood-onset schizophrenia [PDF]

, 2007
We review the development of several new approaches for extending the performance of Brillouin based slow light systems. In particular we describe the use of cavity effects to enhance the achievable delays, gain saturation to decouple the delay and ...
Datta, Soumitra, Kennedy, Eilis, Kumar, Ajit   +2 more
core   +3 more sources

Change in plasma concentration of clozapine and norclozapine following a switch of oral formulation

Therapeutic Advances in Psychopharmacology, 2020
Background: Clozapine formulation has been shown to affect plasma concentrations of clozapine and norclozapine. Changes in formulation might result in toxicity or treatment failure.
Farinaz Keshavarzi, Tony Fox, Eromona Whiskey, David Taylor   +3 more
doaj   +1 more source

Striatal dopamine D2 receptor binding of risperidone in schizophrenic patients as assessed by 123I-iodobenzamide SPECT: a comparative study with olanzapine [PDF]

, 2002
The aim of this investigation was to compare the degree of striatal dopamine-(D2) receptor blockade by two atypical antipsychotic drugs, risperidone and olanzapine.
Arndt J, B. Rossmüller, Dresel S, Duncan G E, E. M. Meisenzahl, G. J. E. Schmitt, Gerlach J, H.-j. Möller, K. Hahn, K. Tatsch, Kapur S, Kerwin R W, Marder S R, Meltzer H Y, Remington G, Richelson E, S. Dresel, T. Frodl, U. W. Preuss   +18 more
core   +1 more source

Do Asian Patients Require Only Half of the Clozapine Dose Prescribed for Caucasians? A Critical Overview

Indian Journal of Psychological Medicine, 2020
Since 1997, studies have found that Asians need lower clozapine doses than Caucasians. Caucasians with average clozapine metabolism may need from 300 to 600 mg/day to reach the therapeutic range (350 ng/ml). Thus, serum clozapine concentration-to-dose (C/
J. de Leon, A. Rajkumar, Arun R Kaithi, G. Schoretsanitis, J. Kane, Chuanyue Wang, Yi-lang Tang, Shih-ku Lin, K. Hong, S. Farooq, C. Ng, Can-Jun Ruan, C. Andrade   +12 more
semanticscholar   +1 more source

Exploiting the molecular diversity of the synapse to investigate neuronal communication: A guide through the current toolkit

European Journal of Neuroscience, Volume 56, Issue 12, Page 6141-6161, December 2022., 2022
Chemical synapses are tiny and overcrowded environments enriched with thousands of protein species. Many efforts have been devoted to developing sensors and actuators able to evaluate and control synaptic communication. Most of these recent tools are based on the engineering of one or more specific synaptic proteins used to target active moieties to ...
Jacopo Lamanna, Mattia Ferro, Sara Spadini, Antonio Malgaroli   +3 more
wiley   +1 more source