Results 51 to 60 of about 73,615 (295)

Clozapine Withdrawal Catatonia: A Case Series and Review of Literature

Annals of Indian Psychiatry
Background: Catatonia has been reported with withdrawal of medications. Among the various psychotropics, clozapine has been implicated to cause catatonia when abruptly withdrawn. The data regarding clozapine withdrawal catatonia are scarce and are mostly
Gopika Jagota, Sandeep Grover
doaj   +1 more source

Managing ciprofloxacin-clozapine interaction with immunoassay-based monitoring: A case report [PDF]

Mental Health Clinician
Whereas the interaction between clozapine and ciprofloxacin is well-documented, this case report emphasizes the importance of closely monitoring clozapine plasma concentrations during concurrent administration.
Kristin Waters, PharmD, BCPS, BCPP, Victoria Popielarz, BS, PharmD Candidate, Joseph Lumasag, BS, PharmD Candidate, Sara Wiesenfeld, BS, PharmD Candidate, Ashley Tewksbury, PharmD, BCPP   +4 more
doaj   +1 more source

Clozapine in pregnancy

Indian Journal of Psychiatry, 2006
This report describes the case of a woman with treatment-resistant schizophrenia who became pregnant while being treated successfully with clozapine. Possible risks associated with continuation of clozapine during pregnancy are discussed.
openaire   +4 more sources

Corticosterone Contributes to Context‐Triggered Retrieval of Morphine Withdrawal Memories by Acting on Basolateral Amygdala Neurons Projecting to Nucleus Accumbens Core

Advanced Science, EarlyView.
Context associated with morphine withdrawal elicits an increase in serum corticosterone levels. Corticosterone participates in CTR‐MWM by acting on MR, but not GR, in the BLA. MR in BLA→NAcC neurons mediates CTR‐MWM. MR increases presynaptic glutamate release and meanwhile participates in D1 receptor‐induced increases in presynaptic glutamate release ...
Zixuan Cao, Yaxian Wen, Yuanqi Chen, Yali Fu, Hao Yang, Chenshan Chu, Xinli Guo, Yu Yuan, Chao Lei, Huan Sheng, Da Shao, Li Yang, Dongyang Cui, Ming Chen, Bin Lai, Ping Zheng   +15 more
wiley   +1 more source

Genetic association analysis of N-methyl-d-aspartate receptor subunit gene GRIN2B and clinical response to clozapine [PDF]

, 2016
OBJECTIVE: Approximately 30% of patients with schizophrenia fail to respond to antipsychotic therapy and are classified as having treatment-resistant schizophrenia.
Abrams, Alonso, Altar, American Psychiatric Association, American Psychiatric Association, American Psychiatric Association, Anson, Arvanov, Asztely, Ayalew, Banerjee, Barrett, Bertilsson, Black, Bleehen, Borgio, Brown, Buka, Cai, Centorrino, Chiu, Corbett, Cosgrove, Creese, Daly, Davis, Di Maria, Dorval, Dudbridge, Elkis, Emsley, Endele, Evins, Fitzgerald, Freed, Galderisi, Gauderman, Gauderman, Ghassabian, Giardino, Gomes, Gunduz-Bruce, Hagg, Hardy, Harrow, Heresco-Levy, Heresco-Levy, Hirai, Hong, Hopkins, Horacek, Hosking, Hoyer, Hwang, Javitt, Jia, Kane, Kargieman, Kay, Kay, Kennedy, Kharazia, Kohlrausch, Komuro, Kubota, Kumra, Kuryatov, Lacro, Lahiri, Lahti, Laube, Lieberman, Lindenmayer, Linn, Liu, Long, Luby, Luisada, Malhotra, Mandich, Manolio, Massey, Mata, Mayer, McAdams, McGlashan, Meltzer, Meltzer, Meshul, Miyamoto, Mortensen, Mortimer, Newman-Tancredi, Ninan, Noda, Nowak, Nyholt, Odom-White, Ossowska, Overall, Overall, Palego, Park, Paschou, Patil, Pearce, Perkins, Pickar, Pilowsky, Pinard, Price, Purcell, Purkayastha, Sadee, Sadee, Sasieni, Schiller, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Schmitt, Schotte, Seeman, Seppala, Shapiro, Solanki, St Clair, Sun, Susser, Szczepankiewicz, Tandon, Theisen, Tian, Tingley, VanLiere, Ventura, Vojvoda, Weinberg, Wittke-Thompson, Wyatt, Xia, Xu, Yamamoto, Yoo, Zhang, Zhao, Zuk   +144 more
core   +1 more source

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang, Taihe Zhou, Yueming Sun, Yuanchen Ma, Yiwen Deng, Keyu Chen, Ruijie Li, Yuan Qiu, Tao Wang, Xiaoyong Chen, Li Huang, Lu Zhu, Xueyi Tu, Ying Wang, Zheming Liu, Rouchen Lin, Yunli Tong, Yuantao Li, Heshe Li, Lin Nie, Rui Fang, Jianqi Feng, Xuhong Wei, Xia Feng, Andy Peng Xiang, Xiaoran Zhang   +25 more
wiley   +1 more source

Patterns of C-reactive protein trends during clozapine titration and the onset of clozapine-induced inflammation: a case series of weekly and daily C-reactive protein monitoring

Frontiers in Psychiatry
BackgroundInternational guidelines for clozapine titration recommend measuring C-reactive protein (CRP) weekly for 4 weeks after clozapine initiation to prevent fatal inflammatory adverse events, including myocarditis.
Yuki Kikuchi, Yuki Kikuchi, Hiroaki Tanifuji, Sota Ueno, Yoshifumi Onuma, Masatomo Goto, Masato Ishihara, Takeshi Toraiwa, Hiroshi Komatsu, Hiroaki Tomita, Hiroaki Tomita   +10 more
doaj   +1 more source

The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects [PDF]

, 2015
Funded by: •GW Pharmaceuticals Acknowledgements: The authors wish to thank Mrs Lesley Stevenson for technical support and Dr John Raymond, Dr Keith Parker and Dr Ethan Russo for providing human 5-HT1A CHO cells.
Cascio, Maria Grazia, Marini, Pietro, Parolaro, Daniela, Pertwee, Roger G., Zamberletti, Erica   +4 more
core   +1 more source

A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness

Advanced Science, EarlyView.
This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu, Sang Soo Lee, Jiali Xiong, Shahin Ahmadi, Benjamin J. Bell, Mehmet F. Keles, Mark N. Wu   +6 more
wiley   +1 more source

Analyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk

Advanced Science, EarlyView.
A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.
Rui Chen, Benjamin Siciliano, Quan Wang, Chongchong Xu, Qiang Wei, Hai Yang, James S Sutcliffe, Yi Jiang, Ying Ji, Chunyu Liu, Feixiong Cheng, Edwin H Cook, Nancy J Cox, Xue Zhong, Zhexing Wen, Bingshan Li   +15 more
wiley   +1 more source